scholarly journals A PLACEBO CONTROLLED COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF JEERAKADYA GHRITA PRAYOGA IN AMLAPITTA WITH SPECIAL REFERENCE TO URDHVAGA AMLAPITTA

2020 ◽  
Vol p5 (01) ◽  
pp. 2563-2569
Author(s):  
Smita M. Choudari ◽  
Rahul R. Kulkarni ◽  
Prasan V. Joshi
Keyword(s):  
Clinical Study ◽  
Special Reference ◽  
Placebo Capsule ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Amlapitta is a disease of Annavaha srotas which is characterized by the symptoms like Avipaka, Klama, Utklesha, Tikta Amlodghara, etc. explained by Acharyas. It is the most disturbing and irritable condition. As the Nidana leading to impairment of Pachakagni causes many diseases like Ajeerna, Aruchi, Agnimandya, Amlapitta etc. Agni is responsible for digestion of food. Amlapitta is Pittapradhana Tridoshaja Vyadhi. Because of the vitiation of Pitta there is Mandagni. Ghrita which is claimed to be Pittashamaka, Dahashamaka and Agnideepaka. So, in the present study the Jeerakadhya Ghrita was taken to treat the Mandagni and vitiated Pittadosha. Jeerakadhya Ghrita, mentioned in Bhaishjya Ratnavali and Chakradatta by the virtue of its Rasa, Guna, Veerya, Vipaka and Samyoga helps in Pitta Shamana, Daha Shamana, Agni Deepana, and Ama Pachana. In the present study, 30 patients diagnosed with Urdhvagha Amlapitta were selected randomly and allocated to Group A and Group B. Group A received Placebo capsule and Group B Jeerakadhya Ghrita. Group A with placebo was studied to compare the efficacy of Jeerakadhya Ghrita was done. Results were analyzed statistically. The study proves that Jeerakadhya Ghrita has a significant effect in Urdhvagha Amlapitta and Non-Digestible Cellulose used as a placebo has no significant effect in Urdhvagha Amlapitta.

scholarly journals A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF KANJIKADI GHRITA AND AMRUTADI GHRITA SNEHAPANA FOR VIRECHANA IN AMAVATA WITH SPECIAL REFERENCE TO RHEUMATOID ARTHRITIS

2021 ◽  
Vol 9 (11) ◽  
pp. 2698-2706
Author(s):  
Kavya J H ◽  
Rajesh Sugur ◽  
Doddabasayya Doddabasayya
Keyword(s):  
Rheumatoid Arthritis ◽  
Comparative Analysis ◽  
Clinical Study ◽  
Special Reference ◽  
T Test ◽  
The Body ◽  
Inclusion Criteria ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Amavata is a Vata and Kapha Pradhana Vyadhi caused due to Viruddha Ahara and Vihara resulting in Mandagni, leading to the formation of Ama. Ama with the influence of Vata Dosha circulates all over the body and gets lodged in Shleshma Sthana in Sandhi Pradesha, resulting in the manifestation of Amavata. Snehapana is a mandatory Poorvakarma before Shodhana. Snehapana does the Uthklesha of Doshas before Shodhana, without which proper achievement of Shuddhi is not possible. Snehapana and Virechana are the main lines of treatment for Amavata. To evaluate the better result, here for Snehapana Kanjakadi Ghrita & Amruthadi Ghrita were taken before Virechana which is then compared and analysed statistically. A minimum of 40 patients, fulfilling the diagnostic and inclusion criteria of Amavata according to Ayurveda classics and based on criteria fixed by the American Rheumatology Association (ARA) in 1988 criteria will be selected and randomly assigned into 2 groups, i.e. Group A and Group B consisting minimum of 20 patients in each group. Comparative analysis of the overall effect of the treatments in both groups was done statistically with the Unpaired T-Test. The test shows that the treatment is statistically not significant in Group A when compared to Group B. Overall result of Group A is 25.08% and the overall result of Group B is 31.07%. Keywords: Amavata, Kanjikadi Ghrita, Amritadi Ghrita, Snehapana, Virechana

Comparative Clinical study of Jatyadi Taila and Jatyadi Ghrita in the management of Dushta Vrana

2018 ◽  
Vol 3 (3) ◽  
Author(s):  
Rajendra Joshi ◽  
N. B. Mashetti ◽  
Rakesh Kumar Gujar
Keyword(s):  
Clinical Study ◽  
Burning Sensation ◽  
Normal Process ◽  
Surgical Practice ◽  
Local Factors ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
Contaminated Wound ◽  
Group B

Dushta Vrana is a common and frequently encountered problem faced in surgical practice. The presence of Dushta Vrana worsens the condition of the patient with different complications and may become fatal. Local factors on wound like slough, infection and foreign body, affect the normal process of healing. A healthy wound in a normal body heals earlier with a minimum scar as compared to a contaminated wound. Therefore in this study all the efforts are made to make a Dushta Vrana into a Shuddha Vrana. Once the Vrana becomes Shuddha, Ropana of the Vrana will start. The objective of the study was to evaluate the clinical efficacy of Jatyadi Taila and Jatyadi Ghrita in Dushta Vrana. Clinically diagnosed 60 Patients of Dushta Vrana were randomly divided into two groups, each consisting of 30 Patients. Group A were treated with the Jatyadi Taila and Group B was treated by Jatyadi Ghrita. The results observed was based on the relief obtained on the subjective and objective parameters taken for consideration for this study viz, size of ulcer, discharge, smell, pain, burning sensation, itching and granulation were found significant (P Lass Than 0.05). On the basis of assessment criteria and overall result of treatment, the patients of Jatyadi Taila group showed better results when compared to Jatyadi Ghrita group. Even though statistically there is no much significant difference between the two groups, but by seeing the effect on individual parameters (subjective and objective) and over all response, Jatyadi Taila seems to be effective when compared to Jatyadi Ghrita. It is having more Ropana qualities when compared to Shodhana.

scholarly journals A Randomized Comparative Clinical Study to evaluate the effect of Bodhi Vruksha Twak Kashaya with Madhu and Guduchi Kashaya in the Management of Vatarakta with special reference to Gouty Arthritis

2020 ◽  
Vol 5 (02) ◽  
pp. 22-29
Author(s):  
K. M. Bhavana ◽  
Umesh C. ◽  
Neelakanta Sajjanar ◽  
Gopala Krishna G.
Keyword(s):  
Special Reference ◽  
Gouty Arthritis ◽  
Signs And Symptoms ◽  
Renal Diseases ◽  
Comparative Clinical Study ◽  
Evolution Of Technology ◽  
Group A ◽  
Group B ◽  
Contemporary Medicine ◽  
Potential Signal

Background: Vatarakta is a disease which is said to affect the population indulging in sedentary lifestyle. In today’s era the evolution of technology has reached a point where pretty much anything is available at the touch of a button. The lifestyle of today’s population is breeding ground for diseases like Vatarakta. Based on the causes, signs and symptoms, Vatarakta may be correlated to gouty arthritis in contemporary medicine. Gout affects about 2.1 million worldwide. Its prevalence is increasing; moreover it is a potential signal for unrecognized co-morbidities like obesity, diabetes mellitus, hypertension and renal diseases. In India the prevalence of gout is 2-6 per 1000. The purpose of this study is to explore and find out an effective, less expensive, easily available and well accepted drug with minimal or no complications for this dreadful condition. Materials and Methods: 40 patients diagnosed with Vatarakta w.s.r Gouty Arthritis were assigned randomly into 2 groups. Group A, were administered Bodhi Vruksha Twak Kashaya 50ml B.I.D with Madhu and Group B were administered Guduchi Kashaya 50ml B.I.D for a duration of 30 days. Assessment was done on day 0, day 15, day 30, and day 45. Observations and Results: In the present study Group A showed statistical significant results in all the parameters except for Sandhishotha and group B showed statistical significant result in Sandhishoola, Sandhidaha, Sparshasahaishnuta and uric acid levels. Conclusion: Overall result shows patients treated with Guduchi Kashaya showed better results than patients treated with Bodhi Vruksha Twak Kashaya with Madhu in Vatarakta with special reference to Gouty Arthritis.

scholarly journals A COMPARATIVE CLINICAL STUDY ON THE EFFECT OF ASHTAVARGAM KASHAYA AND GANDHARVAHASTHADI KASHAYA IN THE MANAGEMENT OF KATIGRAHA w.s.r. TO LUMBAR SPONDYLOSIS

2020 ◽  
Vol 8 (8) ◽  
pp. 4036-4042
Author(s):  
Abeena Raj D P ◽  
Shripathi Acharya
Keyword(s):  
Clinical Study ◽  
Food Habits ◽  
Unhealthy Food ◽  
Lumbar Spondylosis ◽  
Moderate Improvement ◽  
Nutritional Deficit ◽  
Mild Improvement ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Katigraha is a condition in which the vitiated Vata is localizing in the Katipradesha and producing stiff-ness and pain. These symptoms are similar to Lumbar Spondylosis. The degenerative changes due to aging or trauma, changing in lifestyle & work pattern, unhealthy food habits causing nutritional deficit etc., are causing Dhatukshaya and Margavarodha. Here Ashtavarga & Gandharvahasthadi Kashayas are taken to evaluate the effect on Katigraha. Totally 40 patients of Katigraha were selected, divided in to two groups equally. Group A treated with Ashtavargamkashaya and Group B treated with Gandharvahasthadi Kashaya for 30 days. In group A, 55% patients got moderate improvement and 40% patients with mild im-provement in group B, 5%got moderate improvement and 60% got mild improvement. It is concluded that in general statistically significant results were seen in both the groups. AshtavargamKashaya showed better efficacy than Gandharvahasthadikashaya.

scholarly journals A comparative clinical study on the effect of Gudashunti Nasya and Kola Kulattadi Ruksha Sweda in Manyasthamba

2020 ◽  
Vol 5 (03) ◽  
pp. 1-6
Author(s):  
Sandeep K ◽  
Guruprasad G ◽  
Veeraj Hegde
Keyword(s):  
Statistical Analysis ◽  
Clinical Study ◽  
Severe Pain ◽  
Computer Usage ◽  
Before And After ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Classical Symptom

Due to present day lifestyle, a greater number of people are inclined to desk work and computer usage leading to many disorders. Manyasthamba is one among such disorders where the stiffness of neck with severe pain is the classical symptom which hampers our day to day life. While explaining treatment of Manyasthamba our Acharyas explained Rukshasweda and Nasya Karma as main line of treatment. Here a study was done by taking Gudashunti Yoga explained in Sharangadara Samhita indicated for Nasya and Kolakulattadi Churna indicated in Vatavyadhi explained in Ashtanga Sangraha for Ruksha Churna Sweda. A comparative clinical study of 40 patients suffering from Manyastambha were selected after thorough investigation. Patients were subjected to Nasya Karma in Group A and Ruksha Sweda and Nasya Karma in Group B for 7 days. Patients were assessed based on standard parameters before and after treatment and 7 days follow up. The statistical analysis revealed that there was a significant improvement in parameters like pain and stiffness. Hence proving the efficacy in the condition.

scholarly journals A comparative clinical study to access the role of Basti and Virechana Karma followed by Rasayana in post menopausal Asthikshaya (Osteoporosis)

2020 ◽  
Vol 5 (05) ◽  
pp. 96-103
Author(s):  
Deepa S. Patil ◽  
Prashanth A.S
Keyword(s):  
Clinical Study ◽  
Inclusion Criteria ◽  
Comparative Clinical Study ◽  
Group A ◽  
Post Menopausal ◽  
Group B

Rajonivrutti condition manifests in the end phase of Jarawastha; but its Samprapti begins from the Sandhikala of Madhyamawastha and Jarawastha due to Vatavruddi in womens reaching Rajonivrutti. Postmenopausal Asthikshaya is a disabling disease, which renders women a bedridden life. Here 40 subjects diagnosed with postmenopausal Asthikshaya fulfilling the inclusion criteria were selected for the study and randomly categorized intp two groups as group A and group B each consisting of 20 subjects. Group A received Amapachana with Hinguvachadivati, Yastimadhu Siddha Ksheerabasti administered in Yoga Basti schedule followed by Tritiyatriphala Rasayana. Group B received Amapachana with Hinguvachadivati, Sadhyosnehapana with Amrita Ghrita, Sarvanga Abyanga with Murchita Tilataila followed by Sarvanga Swedana and Sneha Virechana was admistered with Eranda Taila followed by Tritiyatriphala Rasayana was given. Tritiya Triphala Rasayana selected for the present study by adapting all the general principles of prevention and management of Asthikshaya and as it is a well known Rasayana.

scholarly journals A Comparative Clinical Study of Trikarshika Kwatha with and without Lifestyle Modification in the Management of Vatarakta with Special Reference to Hyperuricaemia

2021 ◽  
pp. 10-19
Author(s):  
Md Tanzil Ansari ◽  
Sukumar Ghosh ◽  
Shailendra Kumar Singh
Keyword(s):  
Clinical Study ◽  
Lifestyle Modification ◽  
Test Results ◽  
Before And After ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
High Level ◽  
Urate Crystals

Nowadays, people are more vulnerable to metabolic disorders due to their faulty dietary and behavioural habits. One such disorder is Vatarakta which causes functional impairment due to involvement of Sandhi (joints). It is manifested by Ruk, Toda, Sparsha asahatva, Shopha, Raga, Daha and Stabdhata in Sandhi. Vatarakta can be correlated with Hyperuricaemia or Gout due to similarity in their clinical features. Hyperuricaemia is defined as abnormally high level of uric acid in blood (i.e. >6mg/dl in female and >7mg/dl in male). On the other hand, Gout is an inflammatory response to monosodium urate crystals formed secondary to hyperuricaemia. Aims and objectives: 1. To evaluate the effectiveness of Trikarshika kwatha and lifestyle modification in the management of Vatarakta. 2. To compare the effects of Trikarshika kwatha with and without lifestyle modification in the management of Vatarakta. Materials and methods: Raw herbs of the research formulation were collected after proper identification and Kwatha was prepared for oral administration. For the clinical study, total 60 patients were selected on the basis of selection criteria. Selected patients were randomly divided into two groups. (i) Group A: 30 patients were treated with Trikarshika kwatha. (ii) Group B: 30 patients were treated with Trikarshika kwatha along with Lifestyle modification. Individual patient was treated for 45 days along with follow up at the interval of every 15 days. To assess the effectiveness of treatment, scoring pattern was followed for subjective and objective parameters. They were assessed before and after treatment. The collected data were analysed statistically by using Paired t-test. Results: On the basis of all statistical data, it can be said that patients of Group B showed better results in all parameters in comparison to patients of Group A. Conclusion: Both Trikarshika kwatha and Lifestyle modification are affective but Trikarshika kwatha with Lifestyle modification is more effective than Trikarshika kwatha without Lifestyle modification in the management of Vatarakta.

scholarly journals A comparative clinical study between intra-caesarean and interval intra uterine copper device insertion in caesarean deliveries

2019 ◽  
Vol 8 (10) ◽  
pp. 3874
Author(s):  
Geetha Lakshmi R. ◽  
Sornam M. S. ◽  
Thenmozhi G.
Keyword(s):  
Clinical Study ◽  
Infection Rate ◽  
Family Welfare ◽  
Uterine Perforation ◽  
Expulsion Rate ◽  
Insertion Method ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Background: Health and family welfare of Indian Ministry, emphasis on postpartum IUCD insertion. Here we conducted a clinical study comparing intra-caesarean and interval CuT-380A insertion in caesarean deliveries.Methods: A systematic study with 150 patients in each group, recruited clients alternately. Group A Intra-Caesarean Cu-T insertion and Group B Interval Cu-T insertion in caesarean deliveries. Groups were followed up at 6th week and 6th month post insertion with a set of parameters. Missed strings, expulsion and infection rates were the primary outcome measures.Results: Infection rate is higher in Group A (2.3%) at 6th week, and at 6th month infection rate is higher in Group B (1.8%). Missed strings are higher in intra-caesarean than in interval insertion method both at 6th week and 6th month follow up p=0.000, hence significant. Expulsion rate is higher in Group A (2.5%) at 6th week, and at 6th month expulsion rate is higher in Group B (1.9%). There are no complications such as uterine perforation or contraceptive failures in both the groups during the study period. By analysis, there are no significant differences in infection and expulsion rates between the groups. For missed strings there is significant difference between the groups with more missed strings in intra-caesarean insertion method.Conclusions: To conclude, intra-caesarean method is equally effective as interval IUCD insertion method without added complications in caesarean deliveries, with advantage of high motivation, good compliance, safety and ease for the provider to deliver services. 

scholarly journals A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF LAVANGADI GUTIKA AND PIPPALYADI GUTIKA IN KAPHAJA KASA

2021 ◽  
Vol 9 (10) ◽  
pp. 2347-2352
Author(s):  
Risin Sugunan ◽  
Zenica D’souza
Keyword(s):  
Clinical Study ◽  
Chronic Bronchitis ◽  
Early Management ◽  
Normal Life ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
The Subject ◽  
Group B

Kasa is one of the Pranavaha Srothodusti vikara which hinders normal life. Kaphaja Kasa is a type of Kasa with Vata and Kapha as predominant doshas and present with Prabhuta, Ghana and Bahala kapha. Kaphaja Kasa can be best compared with Chronic Bronchitis. If left untreated it leads to various conditions like Swasa, Kshaya, Chardi, Svarasaadha etc. This signifies the importance of its early management. The present study was conducted on 40 diagnosed subjects of Kaphaja Kasa who were randomly allocated into 2 groups with 20 patients each. La- vangadi gutika was taken in Group A and Pippalyadi gutika in Group B. Medicines was given for 30 days and the data was collected from the subject at baseline, 16th day, 31st day and on 46th day (follow up). The result of the study showed that there was a statistically significant difference in the assessment parameters in both the groups from baseline. However no statistically significant difference was observed between the effect of Lavangadi guti- ka and Pippalyadi gutika in the management of Kaphaja Kasa suggesting that both interventions were having a significant effect on the condition.

scholarly journals A comparative clinical study on the efficacy of Nasya with Pinyaka / Panchamula Taila and Swalpa Masha Taila in Apabahuka w.s.r. to frozen shoulder

2020 ◽  
Vol 5 (04) ◽  
pp. 31-36
Author(s):  
Conception Costa ◽  
Sudarshan A. ◽  
Jeejo Chandran O
Keyword(s):  
Clinical Study ◽  
Adhesive Capsulitis ◽  
Frozen Shoulder ◽  
Modern Medicine ◽  
Study Group ◽  
Inclusion Criteria ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Single Blind

Background: Apabahuka is a Vataja Nanatmaja Vyadhi, in which locomotive functions of Amsa Sandhi are affected mainly due to Vata Dosha Prakopa causing pain, stiffness and restricted movement of the shoulder. Apabahuka can be correlated to Frozen shoulder or Adhesive Capsulitis in modern medicine because of similar symptomatology. Nasya is indicated in Urdhwajatrugata Vikaras. Pinyaka Taila and Swalpa Masha Taila are Vatahara Taila used for Nasya. Method: A single blind randomised clinical study in which 40 clinically diagnosed patients of Apabahuka, fulfilling the inclusion criteria were selected and divided into two groups - Group A treated with Pinyaka / Panchamula Taila Nasya and Group B treated with Swalpa Masha Taila Nasya, comprising of 20 patients each. Result: Statistically Nasya with Pinyaka Taila showed better results in Pain (51.2%), Stiffness (48%), Tenderness (58.33%), with improvement in goniometric readings of shoulder ROM than Nasya with Swalpa Masha Taila in Pain (39.4%), stiffness (40.9%), Tenderness (58%). Discussion: Rukshadi Gunas of Vata are increased in Apabahuka hence Viparita Gunas like Snigdhadi in the form of Brumhana Nasya with Pinyaka Taila was found to be effective in Apabahuka. In the present study Group A Nasya with Pinyaka Taila showed better effect than Group B Nasya with Swalpa Masha Taila.

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