scholarly journals JALAUKAVACHARANA IN THE MANAGEMENT OF DIABETIC WOUND (MADHUMEHAJANYADUSHTAVRANA)

2020 ◽  
Vol 08 (11) ◽  
pp. 4982-4986
Author(s):  
Kalpana Verma
Keyword(s):  
Clinical Study ◽  
Clinical Features ◽  
Medical Faculty ◽  
Important Class ◽  
Diabetic Wound ◽  
Clinical Challenge ◽  
The World ◽  
Diabetic Wounds ◽  
Early Healing

Diabetic wounds have failed to proceed through an orderly and timely process to produce anatomic and functional integrity. Wounds form a very extensive and important class of the disease. Diabetic wound re-mains a major clinical challenge to the medical faculty throughout the world. Ayurveda the age old and ho-listic system of medicine offers various tools for management of Vrana. In Ayurveda Acharya Sushruta, pioneer surgeon, have mentioned various types of wound and its management. To achieve good approxi-mation, early healing and acceptable scar, without complications Acharya Susruta has elaborately ex-plained Shashti Upakrama. Rakta mokshana is one of them. Based on this reference, a clinical study was done with patients having clinical features of Madhumehajanyadushta vrana. So, the present study is planned to evaluate the efficacy of Jalaukavacharan in the management of diabetic wound (Madhumeha-janyadushta Vrana). For these 15 patients were selected from O.P.D/ I.P.D of Shalya Tantra, N.I.A., Jai-pur. The treatment was accessed with observation and results for a period of eight weeks. After this thera-py, significant result was observed. It was observed that the results achieved are effective and stable during follow up period.

scholarly journals POS0815 CLINICAL CHARACTERISTICS, IMAGING PHENOTYPE, AND LONG-TERM OUTCOMES OF TAKAYASU ARTERITIS PATIENTS WITH HYPERTENSION

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 661.1-661
Author(s):  
Y. Sun ◽  
L. Ma ◽  
H. Chen ◽  
C. Rongyi ◽  
L. Jiang
Keyword(s):  
Blood Pressure ◽  
Adverse Events ◽  
Clinical Features ◽  
Takayasu Arteritis ◽  
Pressure Control ◽  
Free Survival ◽  
The World ◽  
Cluster 2

Background:Hypertension occurred in 30-80% of TAK patients around the world. The occurrence of hypertension might severely worsen TAK prognosis. Nevertheless, data describing the specific imaging features in hypertensive TAK patients and the associations between hypertensive severity, blood pressure control status and long-term outcome were still lacking.Objectives:To investigate the characteristics and associations of hypertensive characteristics with adverse events-free survival in Takayasu arteritis (TAK) patients with hypertension.Methods:This research was based on a prospectively on-going observational cohort-East China Takayasu Arteritis (ECTA) cohort. In all, 618 TAK patients, who registered in the ECTA cohort up to December 2019, were enrolled. The main outcome was the adverse-events-free survival among hypertensive TAK patients during the follow-up ended on August 2020.Results:Totally, 204 (33.0%) patients suffered from hypertension, with 48 (23.5%), 62 (30.4%), and 94 (46.1%) mild, moderate, and severe hypertension, respectively. Cluster analysis indicated three imaging phenotypes for hypertensive TAK patients: Cluster 1: involvement of the abdominal aorta and/or renal artery (n=56, 27.5%); Cluster 2: involvement of the ascending aorta, thoracic aorta, and the aortic arch and its branches (n=38, 18.6%); Cluster 3: combined involvement of Cluster 1 and Cluster 2 (n=111, 54.4%). By the end of the follow-up, the blood pressure control rate was 50.8%, while the adverse-events-free survival was 67.9% in the entire hypertensive population. Multivariate Cox regression analysis indicated that well-controlled blood pressure (HR=2.13, 95%CI 1.32–3.78, p=0.047), co-existence of severe aortic valve regurgitation (HR=0.87, 95%CI 0.64–0.95, p=0.043), Cluster 1 (HR=0.69, 95%CI 0.48–0.92, p=0.017) and Cluster 3 (HR=0.72, 95%CI 0.43–0.94, p=0.048) imaging phenotype was associated with the adverse-events-free survival.Conclusion:Patients with controlled hypertension showed better adverse-events-free survival, while those with the Cluster 1 imaging phenotype were more likely to suffer from worse adverse-events-free survival. Hypertension occurred in 30-80% of TAK patients around the world. The occurrence of hypertension might severely worsen TAK prognosis.References:[1]Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol 2002; 55:481–6.[2]Watanabe Y, Miyata T, Tanemoto K. Current clinical features of new patients with Takayasu arteritis observed from a cross-country research in Japan: age and sex specificity. Circulation 2015; 132:1701–9.[3]Yilmaz N, Can M, Oner FA, et al. Impaired quality of life, disability and mental health in Takayasu’s arteritis. Rheumatol. (Oxford) 2013; 52:1898–904.[4]Laurent A, Julien H, Nicolas L, et al. Takayasu arteritis in France: a single-center retrospective study of 82 cases comparing white, North African, and black patients. Medicine 2010; 89:1–17.[5]Mwipatayi BP, Jeffery PC, Beningfield SJ, et al. Takayasu arteritis: clinical features and management: report of 272 cases. ANZ J Surg 2005; 75:110–7.Disclosure of Interests:None declared

scholarly journals A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF DARVYADI LEHYA AND DRAKSHADI LEHYA IN PANDU ROGA W.S.R TO I.D.A

2020 ◽  
Vol 8 (9) ◽  
pp. 4324-4328
Author(s):  
Karthika Raj ◽  
Susheel Shetty
Keyword(s):  
Clinical Practice ◽  
Clinical Study ◽  
Data Base ◽  
Clinical Features ◽  
The Other ◽  
Significant Difference ◽  
The World ◽  
Before And After ◽  
Comparative Clinical Study ◽  
Global Data

Pandu is a Pitta Pradhana Tridoshaja Vikara affecting the Rasavaha srotas causing Sapta Dhatu Kshaya and Ojokshaya1. The disease is characterized by Panduvamata and Arohana Ayasa. Karnakshweda, Agnimandya, Daurbalya, Annadwesha, Srama, Bhrama, Gathrashoola, Arohanaayasa, Aruchi, Gaurava etc. are the other symptoms commonly found in the patients of Pandu. In the Present era, Anaemia is a burning issue around the world and W.H.O Global data base 2011 reveals that, in a 120 million population, 83% people are suffering from anaemia2.Present study was conducted on 60 diagnosed patients of Panduwho were randomly allocated with 30 each in two groups. Darvyadhi Lehya was given for one group and Drakshadhi Lehya a widely used formulation in clinical practice was given for another group. The study was conducted in 60 subjects for a period of 30 days. Clinical features and haematological parameters were documented before and after the treatment. The results of the study showed that, a statistically significant difference was not seen between the effect of Darvyadi and Drakshadilehya in Pandu roga.

scholarly journals A CLINICAL STUDY TO EVALUATE THE EFFECT OF DADRUGHNA PATRA TAILA IN DADRU KUSHTA

2021 ◽  
pp. 110-120
Author(s):  
Lakshmi S P ◽  
Harini A
Keyword(s):  
Clinical Study ◽  
Antifungal Activity ◽  
Key Words ◽  
Clinical Features ◽  
Skin Diseases ◽  
External Application ◽  
Cassia Alata ◽  
Effect Of Therapy ◽  
Lesion Severity

Introduction: All the skin diseases in Ayurveda have been classified under the broad heading, “Kushta”. Dadru is one among Kushta. It involves the clinical features like kandu, raga, pidaka, utsannamandala. Dadru kushta mostly simulates with ‘Dermatophytosis’ commonly referred to as ringworm which is highly contagious. In this study an effort has been made to evaluate the Dadrughna karma (Antifungal activity) of the oil prepared from Dadrughna (Cassia alata Linn) leaves. Materials and methods: In the present study, action of Dadrughna (Cassia alata Linn) patra taila on Dadru kushta was evaluated in 32 subjects who were treated with Dadrughna patra taila as an external application twice a day for 30 days and follow up was done on 45th day. Assessment was done for subjective parameter-itching and objective parameters-distribution of lesion, severity of inflammation, extent of lesion. Results: The effect of therapy was assessed before treatment, 15th day, 30th day of treatment and follow up was done on 45th day. The results were statistically analyzed; it showed significant changes in subjective parameter-itching (p<0.001) and Objective parameters- distribution of lesion (p <0.001), severity of inflammation (p<0.001), extent of lesion (p <0.001). Discussion and conclusion: The external application of Dadrughna patra taila applied for 30 days has helped in reduction of itching, distribution of lesion, extent of inflammation and severity of inflammation where the taila was found more effective in reducing itching when compared to other symptoms KEY WORDS: Dadru kushta, Dermatophytosis, Dadrughna (Cassia alata Linn), Dadrughna patra taila

scholarly journals A case study of jalaukavacharan in management of non healing diabetic ulcer

2018 ◽  
Vol 6 (02) ◽  
Author(s):  
Gaurav Ramavatar Gupta ◽  
Shubhangi Badole ◽  
Sanjeev Yadav
Keyword(s):  
Clinical Study ◽  
Wound Management ◽  
Diabetic Ulcer ◽  
Medical College ◽  
Early Healing

TITLE- Efficacy of Jalaukavacharan in Management of Non Healing Diabetic Ulcer. HYPOTHESIS- Jalaukavacharan has significant effect in non-healing diabetic ulcer. OBJECTIVE- Acharya Sushruta has elaborately explained shashti upakrama for wound management to achieve good approximation, early healing and acceptable scar, without complications out of which one is rakta mokshana. Based on this reference, a clinical study was done with patients having non healing diabetic ulcer. So the present study is planned to evaluate the efficacy of Jalaukavacharan in the management of non-healing diabetic ulcer. METHOD- 15 Patients were selected from O.P.D/I.P.D of Shalya Tantra of Y.M.T Ayurvedic Medical College Kharghar. The treatment was accessed with observation and results for period of eight weeks. RESULT- After this therapy, significant result was observed. CONCLUSION- It was observed that the results achieved are effective and stable during follow up period.  

scholarly journals A prospective study to compare the effectiveness of saline dressing versus povidone iodine dressing in chronic diabetic wound healing: study from a tertiary hospital in south India

2017 ◽  
Vol 4 (4) ◽  
pp. 1371
Author(s):  
Ellikunnel Vithon Gopi ◽  
Amrut H. Basava ◽  
Siddharth Matad
Keyword(s):  
Povidone Iodine ◽  
Treated Group ◽  
Tertiary Hospital ◽  
Complete Healing ◽  
Diabetic Wound ◽  
Medical College ◽  
Diabetic Wound Healing ◽  
A Prospective Study ◽  
Diabetic Wounds

Background: Saline dressings and povidone iodine dressings have been traditionally used for the management of chronic diabetic wounds Methods: Subjects attending diabetic wound clinic and surgery outpatient department/ casualty of Government Medical College and Hospital, Kozhikode, Kerala, India were divided into two groups by consecutive sampling i.e., Povidone iodine and Saline dressing group. Regular occlusive dressing was done for 6 weeks of follow-up period.Results: 3 out of 20 subjects in Saline treated group achieved complete healing by 6 weeks as compared to 1 out of 20 subjects in Povidone iodine treated group. There was a significant decrease in the wound surface area at 6th week in Saline dressing group in comparison to the povidone iodine group at P = 0.03 (<0.05) level of significance.Conclusions: Saline dressing is more effective in achieving healing in chronic diabetic wounds as compared to Povidone iodine dressing.

A combined lateral-crestal approach of sinus floor elevation: A report on three cases

2020 ◽  
Author(s):  
Xin Zhang ◽  
Yuting Zhang ◽  
Jian Wang ◽  
Qianbing Wan ◽  
Lei Li
Keyword(s):  
Clinical Study ◽  
Conservative Treatment ◽  
Lateral Approach ◽  
Clinical Report ◽  
Sinus Lift ◽  
Sinus Floor Elevation ◽  
Long Term Follow Up ◽  
Sinus Floor

This clinical report describes a combined lateral-crestal approach to elevate the sinus floor when placing implants on a wide maxillary posterior ridge. The buccally enlarged osteotomy broadens vision of practitioners and facilitates access of instruments in the sinus. Compared to the traditional lateral approach of sinus lift, the proposed technique may offer a more conservative treatment modality. And a clinical study with sufficient subjects and long term follow up is needed to validate the potential and limitations of the proposed technique.

CLINICAL FEATURES, INDICATIONS AND RESULT OF TRACHEOTOMY

2017 ◽  
pp. 50-55
Author(s):  
Duc Luu Ngo ◽  
Tu The Nguyen ◽  
Manh Hung Ho ◽  
Thanh Thai Le
Keyword(s):  
Clinical Features ◽  
University Hospital ◽  
Female Ratio ◽  
Tube Obstruction ◽  
Level Ii ◽  
Study Results ◽  
Male Female Ratio ◽  
Hospital Patients ◽  
Level I

Background: This study aims to survey some clinical features, indications and results of tracheotomy at Hue Central Hospital and Hue University Hospital. Patients and method: Studying on 77 patients who underwent tracheotomy at all of departments and designed as an prospective, descriptive and interventional study. Results: Male-female ratio was 4/1. Mean age was 49 years. Career: farmer 44.2%, worker 27.2%, officials 14.3%, student 7.8%, other jobs 6.5%. Respiratory condition before tracheotomy: underwent intubation 62.3%, didn’t undergo intubation 37.7%. Period of stay of endotracheal tube: 1-5 days 29.2%, 6-14 days 52.1%, >14 days 18.7%. Levels of dyspnea before tracheotomy: level I 41.4%, level II 48.3%, level III 0%, 10.3% of cases didn’t have dyspnea. Twenty cases (26%) were performed as an emergency while fifty seven (74%) as elective produces. Classic indications (37.7%) and modern indications (62.3%). On the bases of the site, we divided tracheostomy into three groups: high (0%), mid (25.3%) and low (74.7%). During follow-up, 44 complications occurred in 29 patients (37.7%). Tracheobronchitis 14.3%, tube obstruction 13%, subcutaneous empysema 10.4%, hemorrhage 5%, diffcult decannulation 5.2%, tube displacement 3.9%, canule watery past 2.6%, wound infection 1.3%. The final result after tracheotomy 3 months: there are 33 patients (42.9%) were successfully decannulated. In the 33 patients who were successfully decannulated: the duration of tracheotomy ranged from 1 day to 90 days, beautiful scar (51.5%), medium scar (36.4%), bad scar (12.1%). Conclusions: In tracheotomy male were more than female, adult were more than children. The main indication was morden indication. Tracheobronchitis and tube obstruction were more common than other complications. Key words: Tracheotomy

A bioglass sustained-release scaffold with ECM-like structure for enhanced diabetic wound healing

Nanomedicine ◽  
2020 ◽  
Vol 15 (23) ◽  
pp. 2241-2253
Author(s):  
Pengju Zhang ◽  
Yuqi Jiang ◽  
Dan Liu ◽  
Yan Liu ◽  
Qinfei Ke ◽  
...  
Keyword(s):  
Wound Healing ◽  
Therapeutic Option ◽  
Effective Strategy ◽  
Diabetic Wound ◽  
Nano Structure ◽  
Wound Site ◽  
Diabetic Wound Healing ◽  
Coaxial Fibers ◽  
Diabetic Wounds ◽  
Endothelial Cell Adhesion

Aim: To develop an effective strategy for increasing angiogenesis at diabetic wound sites and thereby accelerating wound healing. Materials & methods: A micropatterned nanofibrous scaffold with bioglass nanoparticles encapsulated inside coaxial fibers was prepared by electrospinning. Results: Si ions could be released in a sustained manner from the scaffolds. The hierarchical micro-/nano-structure of the scaffold was found to act as a temporary extracellular matrix to promote endothelial cell adhesion and growth. The scaffold greatly improved angiogenesis and collagen deposition at the wound site, which shortened the healing period of diabetic wounds. Conclusion: This study provides a promising therapeutic option for chronic diabetic wounds with improved angiogenesis.

5-year follow-up of a prospective clinical study on various types of core restorations

2005 ◽  
Vol 94 (4) ◽  
pp. 403 ◽  
Author(s):  
N.H. Creugers ◽  
A.G. Mentink ◽  
W.A. Fokkinga ◽  
C.M. Kreulen
Keyword(s):  
Clinical Study ◽  
Prospective Clinical Study
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