scholarly journals Molekularna detekcija i filoegenijska analiza adenovirusa povezanog s fatalnom bolesti juvenilnih bradatih agama (Pogona vitticeps) u Hrvatskoj

2021 ◽  
Vol 53 (4) ◽  
Author(s):  
Vladimir Savić
Keyword(s):  
Pogona Vitticeps

Australski su gušteri, bradate agame (Pogona vitticeps), vrlo popularni kućni ljubimci koji se uzgajaju u zatočeništvu u brojnim zemljama, a međunarodna trgovina ove vrste guštera nije zanemariva. Bradate agame su osjetljive na infekciju adenovirusom agamida tipa 1 (BDAdv-1) čiji je uzročnik usko povezan s raznim kliničkim znacima poput: iznenadne smrti, letargije, slabosti, proljeva, dehidracije, anoreksije, zaostajanja u rastu i neuroloških simptoma koji nastaju zbog oštećenja jetara. Opisana je fatalna bolest dviju juvenilnih bradatih agama u Hrvatskoj tijekom koje je detektirana infekcija adenovirusom. Osim slabosti, anoreksije, kaheksije i dehidracije, u jedne agame je bio naglašen opistotonus. U fecesu agama je postupkom lančane reakcije polimerazom dokazan adenovirus, dok je nukleotidnim sekvenciranjem i filogenijskom analizom nađena visoka podudarnost s BDAdv-1 izolatima iz bradatih agama u SAD-u, Austriji i Njemačkoj (>99,6 %-100 %), ali i s BDAdv-1 iz slobodnoživućih bradatih agama u Australiji (>99,2 %). Pokušaj izdvajanja virusa kroz dvije pasaže u pačjim embrijima ili deset pasaža u kokošjim embrijima nije dao pozitivan rezultat.

A Description of Isospora amphiboluri (Apicomplexa: Eimeriidae) from the Inland Bearded Dragon, Pogona vitticeps (Sauria: Agamidae)

1995 ◽  
Vol 81 (2) ◽  
pp. 281 ◽  
Author(s):  
Chris T. McAllister ◽  
Steve J. Upton ◽  
Elliott R. Jacobson ◽  
Wayne Kopit
Keyword(s):  
Bearded Dragon ◽  
Pogona Vitticeps

Evaluating Quikon® Med as a Coccidiocide for Inland Bearded Dragons (Pogona vitticeps)

2006 ◽  
Vol 15 (4) ◽  
pp. 269-273 ◽  
Author(s):  
C. Brad Singleton ◽  
Mark Mitchell ◽  
Shannon Riggs ◽  
Orlando Diaz
Keyword(s):  
Pogona Vitticeps

Dynamics of epigenetic modifiers and environmentally sensitive proteins in a reptile with temperature induced sex reversal

2021 ◽  
Author(s):  
Sarah Whiteley ◽  
Robert D McCuaig ◽  
Clare E Holleley ◽  
Sudha Rao ◽  
Arthur Georges
Keyword(s):  
Sex Reversal ◽  
Molecular Characteristics ◽  
Environmental Response ◽  
Specific Expression ◽  
Epigenetic Modifiers ◽  
Cellular Localisation ◽  
Reptile Species ◽  
Environmentally Sensitive ◽  
Pogona Vitticeps

Abstract The mechanisms by which sex is determined, and how a sexual phenotype is stably maintained during adulthood, has been the focus of vigorous scientific inquiry. Resources common to the biomedical field (automated staining and imaging platforms) were leveraged to provide the first immunofluorescent data for a reptile species with temperature induced sex reversal. Two four-plex immunofluorescent panels were explored across three sex classes (sex reversed ZZf females, normal ZWf females, and normal ZZm males). One panel was stained for chromatin remodelling genes JARID2 and KDM6B, and methylation marks H3K27me3, and H3K4me3 (Jumonji Panel). The other CaRe panel stained for environmental response genes CIRBP and RelA, and H3K27me3 and H3K4me3. Our study characterised tissue specific expression and cellular localisation patterns of these proteins and histone marks, providing new insights to the molecular characteristics of adult gonads in a dragon lizard Pogona vitticeps. The confirmation that mammalian antibodies cross react in P. vitticeps paves the way for experiments that can take advantage of this new immunohistochemical resource to gain a new understanding of the role of these proteins during embryonic development, and most importantly for P. vitticeps, the molecular underpinnings of sex reversal.

Single-dose pharmacokinetics of orally administered terbinafine in bearded dragons (Pogona vitticeps) and the antifungal susceptibility patterns of Nannizziopsis guarroi

2021 ◽  
pp. 1-8
Author(s):  
Michael S. McEntire ◽  
Jennifer M. Reinhart ◽  
Sherry K. Cox ◽  
Krista A. Keller
Keyword(s):  
Single Dose ◽  
High Performance ◽  
Clinical Decision Making ◽  
Peak Plasma ◽  
Antifungal Susceptibility ◽  
Plasma Concentrations ◽  
Clinical Decision ◽  
Oral Solution ◽  
Susceptibility Data ◽  
Pogona Vitticeps

Abstract OBJECTIVE To identify the antifungal susceptibility of Nanniziopsis guarroi isolates and to evaluate the single-dose pharmacokinetics of orally administered terbinafine in bearded dragons. ANIMALS 8 healthy adult bearded dragons. PROCEDURES 4 isolates of N guarroi were tested for antifungal susceptibility. A compounded oral solution of terbinafine (25 mg/mL [20 mg/kg]) was given before blood (0.2 mL) was drawn from the ventral tail vein at 0, 4, 8, 12, 24, 48, 72, and 96 hours after administration. Plasma terbinafine concentrations were measured with high-performance liquid chromatography. RESULTS The antifungal minimum inhibitory concentrations against N guarroi isolates ranged from 4,000 to > 64,000 ng/mL for fluconazole, 125 to 2,000 ng/mL for itraconazole, 125 to 2,000 ng/mL for ketoconazole, 125 to 1,000 ng/mL for posaconazole, 60 to 250 ng/mL for voriconazole, and 15 to 30 ng/mL for terbinafine. The mean ± SD peak plasma terbinafine concentration in bearded dragons was 435 ± 338 ng/mL at 13 ± 4.66 hours after administration. Plasma concentrations remained > 30 ng/mL for > 24 hours in all bearded dragons and for > 48 hours in 6 of 8 bearded dragons. Mean ± SD terminal half-life following oral administration was 21.2 ± 12.40 hours. CLINICAL RELEVANCE Antifungal susceptibility data are available for use in clinical decision making. Results indicated that administration of terbinafine (20 mg/kg, PO, q 24 to 48 h) in bearded dragons may be appropriate for the treatment of dermatomycoses caused by N guarroi. Clinical studies are needed to determine the efficacy of such treatment.

ADNEXAL CYSTADENOMA IN A BEARDED DRAGON ( POGONA VITTICEPS )

2018 ◽  
Vol 27 (2) ◽  
pp. 85-89
Author(s):  
Silvia G. Pryor ◽  
Daniel Cutler ◽  
Wilson Yau ◽  
Kathryn A. Diehl
Keyword(s):  
Bearded Dragon ◽  
Pogona Vitticeps

scholarly journals A Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature

2019 ◽  
Vol 69 (3) ◽  
pp. 360-368
Author(s):  
Alessandra Gavazza ◽  
Livio Galosi ◽  
Veronica Croce ◽  
Amerio Croce ◽  
Carla Genovese ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Lymphocytic Leukemia ◽  
Lymphoid Cells ◽  
Immunocytochemical Staining ◽  
Review Of Literature ◽  
Blood Smears ◽  
Bearded Dragon ◽  
Pogona Vitticeps ◽  
Lymphoid Infiltration ◽  
Lymphoblastic Cells

Abstract The present paper reports the case of a 3 years old, female Bearded Dragon (Pogona vitticeps) presenting lethargy, anorexia, weight loss, and anemia and marked leukocytosis at CBC. The majority of leukocytes were lymphocytic/lymphoblastic cells (97%). Immunocytochemical staining of blood smears marked for CD3 (neg) and CD79a (pos) suggested immunophenotype B. The patient died after one month from diagnosis. Histology evidenced lymphoid infiltration in the heart, spleen, liver, kidneys and gut. In addition, in the bone marrow a massive infiltration of lymphoid cells confirmed the diagnosis of leukemia. Immunohistochemistry confirmed the CD79a positivity of a large part of infiltrating lymphoid cells indicating a B cells immunophenotype of the neoplastic population. The presence of lymphocytosis and multiorgan infiltration supported the diagnosis of lymphocytic leukemia. Finally, a revision of the literature has also been made.

scholarly journals Thermoregulatory consequences of salt loading in the lizard Pogona vitticeps

2015 ◽  
Vol 218 (8) ◽  
pp. 1166-1174 ◽  
Author(s):  
C. da Silveira Scarpellini ◽  
K. C. Bicego ◽  
G. J. Tattersall
Keyword(s):  
Salt Loading ◽  
Pogona Vitticeps
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