scholarly journals Species Distribution and Antifungal Susceptibility of Candida Species Isolated From Blood Cultures (2012-2015)

2015 ◽  
Vol 06 (Supplement 6) ◽  
Keyword(s):  
Species Distribution ◽  
Candida Species ◽  
Antifungal Susceptibility ◽  
Blood Cultures

Distribution and antifungal susceptibility of candida species isolated from blood culture

2021 ◽  
pp. 1-12
Author(s):  
Selim Gorgun ◽  
Melek Bilgin ◽  
Suleyman Sirri Kilic ◽  
Admin
Keyword(s):  
Candida Species ◽  
Antifungal Susceptibility ◽  
Tube Formation ◽  
Resistance Rate ◽  
Blood Cultures ◽  
Dilution Method ◽  
Ethical Approval ◽  
Immunosuppressed Patients ◽  
Training And Research ◽  
Vitek 2

Abstract Objective: The aim of this study is to determine the distribution of samples exhibiting Candida growth among the blood cultures, and the antifungal susceptibility. Methods: The retrospective study was conducted in Samsun Training and Research Hospital, Samsun, Turkey from January to December, 2018 and comprised immunosuppressed patients with sepsis. Ethical approval was obtained and consent was taken from all patients. Yeast growths were typed by means of colony morphology, germ tube formation and the VITEK 2 system. Their susceptibilities tests were determined using the same automatized system. Resistance strains were also tested using the dilution method. Results: Of the 50 patients, 19(38%) were females and 31(62%) were males. The overall mean age was 60.84 ± 22.05 years. 31 (62%) of the samples were received from intensive care units, 14 (28%) from the palliative care unit, and five from other inpatients.  In our study, most common among our isolates was C. albicans, and C. parapsiosis was most common among non-albicans species. Resistance to antifungals was observed in 28% of Candida isolates. Of the total isolates, %10 were found to be naturally resistant to fluconazole, 8% to voriconazole, 4% to flucytosine, and amphotericin B. The high resistance rate for fluconazole in Candida species is noteworthy. The findings obtained through both the dilution method and the automatized system were consistent. Continuou....

scholarly journals Species distribution of yeasts recovered from different clinical samples Addiss Ababa,Ethiopia

2019 ◽  
Author(s):  
Elias Seyoum Deribe ◽  
Adane Bitew ◽  
Amete Mihret
Keyword(s):  
Species Distribution ◽  
Candida Species ◽  
Fungal Infections ◽  
Addis Ababa ◽  
Antifungal Susceptibility ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Clinical Samples ◽  
Cross Sectional ◽  
Reported Data

Abstract Background Currently, fungal diseases of humans are among the most problematic illnesses is the result of an increase in opportunistic fungal infections caused by rise in the number of immune-compromised patients. Particularly, yeasts are the most common cause of fungal infections leading to a range superficial type to life-threatening invasive infections. The aim of this study is to determine species distribution of yeasts particularly of Candida species recovered from different clinical samples. Method A cross sectional study was conducted from January 01, 2018 –September 30, 2018 in Addis Ababa, Arsho laboratory. Oropharengial swabs, nail scrapings, sputum, corneal scrapings, and vaginal swabs were collected from patients with signs and symptoms of infections. Identification and antifungal susceptibility testing was performed by using YST card through VITEK 2 compact system. Data was entered and analyzed using SPSS version 20. Result A total of 209 yeasts were recovered of which 49.8% were Candida albicans, 43.1% were non-albicans candida species and 7.2% were yeasts other than Candida species. The current study, eighteen (18) different types of yeast species were identified from different clinical samples. All recognized yeast considered as a causative agent of fungal infection in previously reported data in worldwide. Conclusion C. albicans remaining the predominant species, but the emergence of non-albicans Candida and other than candida species have increased. Thus, more studies on Candida prevalence are needed throughout country.

scholarly journals Species distribution of yeasts recovered from different clinical samples Addiss Ababa,Ethiopia

2019 ◽  
Author(s):  
Elias Seyoum Deribe ◽  
Adane Bitew ◽  
Amete Mihret
Keyword(s):  
Species Distribution ◽  
Candida Species ◽  
Fungal Infections ◽  
Addis Ababa ◽  
Antifungal Susceptibility ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Clinical Samples ◽  
Cross Sectional ◽  
Reported Data

Abstract Background Currently, fungal diseases of humans are among the most problematic illnesses is the result of an increase in opportunistic fungal infections caused by rise in the number of immune-compromised patients. Particularly, yeasts are the most common cause of fungal infections leading to a range superficial type to life-threatening invasive infections. The aim of this study is to determine species distribution of yeasts particularly of Candida species recovered from different clinical samples. Method A cross sectional study was conducted from January 01, 2018 –September 30, 2018 in Addis Ababa, Arsho laboratory. Oropharengial swabs, nail scrapings, sputum, corneal scrapings, and vaginal swabs were collected from patients with signs and symptoms of infections. Identification and antifungal susceptibility testing was performed by using YST card through VITEK 2 compact system. Data was entered and analyzed using SPSS version 20. Result A total of 209 yeasts were recovered of which 49.8% were Candida albicans, 43.1% were non-albicans candida species and 7.2% were yeasts other than Candida species. The current study, eighteen (18) different types of yeast species were identified from different clinical samples. All recognized yeast considered as a causative agent of fungal infection in previously reported data in worldwide. Conclusion C. albicans remaining the predominant species, but the emergence of non-albicans Candida and other than candida species have increased. Thus, more studies on Candida prevalence are needed throughout country.

scholarly journals Distribution and Antifungal Sensitivity of Candida Isolates Detected in Blood Cultures

ANKEM Dergisi ◽  
2020 ◽  
Author(s):  
Duygu Beder ◽  
Fatma Esenkaya Taşbent ◽  
Metin Doğan
Keyword(s):  
Intensive Care ◽  
Candida Species ◽  
Antifungal Susceptibility ◽  
Rapid Identification ◽  
Blood Cultures ◽  
Automated System ◽  
Candida Spp ◽  
Intensive Care Patients ◽  
Gram Staining

Candidemia is a serious clinical condition that can result in mortality. This condition is particularly common in intensive care patients. This retrospective study aimed to identify Candida strains isolated from blood cultures and to determine antifungal susceptibility patterns. For this purpose, isolated Candida species were identified and, their susceptibility to amphotericin B, caspofungin, flucytosine, fluconazole, micafungin and voriconazole were investigated. VITEK 2 automated system was used to identify and detect antifungal susceptibility of Candida species that were subjected to Gram staining and germ tube tests on Candida species detected from blood cultures sent to our laboratory between January 2014 and December 2018. Candida spp. isolation rate was found most frequently (n=157; 64.9 %) in intensive care units; followed by internal clinics (n=64; 26.5 %) and surgical clinics (n=21; 8.6 %). The most frequently isolated species among these Candida isolates are Candida albicans (100/242; 41.3 %) and Candida parapsilosis (92/242; 38 %). Especially in intensive care patients, rapid identification of Candida species and determination of their antifungal susceptibilities are important for planning treatment. It is thought that collecting data reflecting regional resistance status at certain intervals will be guiding in terms of treatment approaches.

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