Investigation of Species Distribution and Antifungal Susceptibility of Candida Species Isolated from Various Clinical Samples From Intensive Care Unit Patients

2016 ◽  
Vol 7 (2) ◽  
pp. 49-52 ◽  
Author(s):  
Suleyman Pelit ◽  
Meltem Uzun
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Species Distribution ◽  
Candida Species ◽  
Antifungal Susceptibility ◽  
Clinical Samples

scholarly journals Prevalence, species distribution, and risk factors of fungal colonization and infection in patients at a burn intensive care unit in Vietnam

2020 ◽  
Author(s):  
Bang Nguyen ◽  
Nguyen Thanh Xuan ◽  
Dinh Xuan Quang ◽  
Cao Ba Loi ◽  
Nguyen Thai N Minh ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Fungal Infection ◽  
Candida Species ◽  
Clinical Information ◽  
Common Species ◽  
Clinical Samples ◽  
Fungal Colonization ◽  
Burn Patients ◽  
Severe Injuries

Background and Purpose: Burn patients are at a higher risk of infections caused by different organisms. This study aimed to address the prevalence, causative species, and factors related to fungal colonization or infection in patients with acute severe injuries admitted to the intensive care unit (ICU) of a burn hospital in northern Vietnam. Materials and Methods: This prospective study was conducted on 400 patients in a burn ICU between 2017 and 2019. Clinical samples were weekly collected and screened for fungi, and relevant clinical information was obtained from medical records. Results: According to the results, 90% of the patients were colonized with fungi. Out of this group, 12.75% of the cases had invasive fungal infection (IFI). Eleven yeasts and six mold species were isolated from the patients, with the most common species being Candida tropicalis (45.56%) and C. albicans (41.94%). Among the eleven species causing fungal wound infection (FWI), the most common agents were Candida (66.7% of FWI patients) and Aspergillus (38.5%) species. Three Candida species isolated from blood were C. tropicalis (66.7%), C. albicans (20.0%), and C. parapsilosis (14.3%). No factors were found to expose the patients to a higher risk of fungal colonization. However, hyperglycemia, prolonged ICU stay, and heavy Candida species colonization were found to be independently predictive of IFI. Conclusion: Burn patients are at the risk of fungal infection with Candida species (especially C. tropicalis) and Aspergillus as the most frequently responsible agents. Continuous surveillance of fungi and appropriate management of pathophysiological consequences are essential to prevent fungal infection in burn patients.

scholarly journals Spectrum of candidal species isolated from neonates admitted in an Intensive Care Unit of teaching hospital of Kashmir, North India

2018 ◽  
Vol 10 (03) ◽  
pp. 255-259 ◽  
Author(s):  
Asifa Nazir ◽  
Talat Masoodi
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Candida Species ◽  
Neonatal Intensive Care ◽  
Life Support ◽  
Antifungal Susceptibility ◽  
Preterm Births ◽  
North India ◽  
Sensitivity Testing ◽  
Vitek 2

ABSTRACT BACKGROUND: Candidal infections are an important cause of morbidity and mortality in Neonatal Intensive Care Unit. Neonatal candidiasis is increasing in frequency, mainly because of increase in the survival of babies with low-birth weight, preterm births, advancement in medical field, life support systems, relative immunodeficiency, and extensive use of broad-spectrum antibiotics. Over the past few decades, there has been a progressive shift from the predominance of Candida albicans to nonalbicans Candida species. AIMS AND OBJECTIVES: The objective of the current study was to know the prevalence of nonalbicans candidemia in neonates and their antifungal susceptibility pattern. Materials and Methods: In this study, a total of 424 samples from clinically diagnosed septicemic neonates were included. Identification of Candida isolates from these samples as well as their antifungal sensitivity testing was performed with Vitek 2 Compact (Biomerieux France) using Vitek 2 cards for identification of yeast and yeast-like organisms (ID-YST cards). Results: A total of 246/424 (58.01%) cases were blood culture positive. Out of these, 80/246 samples tested positive for candidemia (32.5%). Candida tropicalis (13.8%) was the predominant species isolated among the non-albicans Candida followed by Candida krusei (4.8%), Candida parapsilosis (3.2%), Candida guilliermondii (2.8%), and Candida dubliniensis (2.0%). We found an increase in the antifungal drug resistance, especially for the azole group of drugs, both in C. albicans and non-albicans Candida species. All the isolates were uniformly sensitive to micafungin, voriconazole, and caspofungin. Conclusions: Candidemia in neonates is an ominous prognostic sign and is an important entity in our region. The present study highlights the mycological shift of Candida species in neonatal candidemia with a preponderance of nonalbicans Candida species.

scholarly journals Species distribution of yeasts recovered from different clinical samples Addiss Ababa,Ethiopia

2019 ◽  
Author(s):  
Elias Seyoum Deribe ◽  
Adane Bitew ◽  
Amete Mihret
Keyword(s):  
Species Distribution ◽  
Candida Species ◽  
Fungal Infections ◽  
Addis Ababa ◽  
Antifungal Susceptibility ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Clinical Samples ◽  
Cross Sectional ◽  
Reported Data

Abstract Background Currently, fungal diseases of humans are among the most problematic illnesses is the result of an increase in opportunistic fungal infections caused by rise in the number of immune-compromised patients. Particularly, yeasts are the most common cause of fungal infections leading to a range superficial type to life-threatening invasive infections. The aim of this study is to determine species distribution of yeasts particularly of Candida species recovered from different clinical samples. Method A cross sectional study was conducted from January 01, 2018 –September 30, 2018 in Addis Ababa, Arsho laboratory. Oropharengial swabs, nail scrapings, sputum, corneal scrapings, and vaginal swabs were collected from patients with signs and symptoms of infections. Identification and antifungal susceptibility testing was performed by using YST card through VITEK 2 compact system. Data was entered and analyzed using SPSS version 20. Result A total of 209 yeasts were recovered of which 49.8% were Candida albicans, 43.1% were non-albicans candida species and 7.2% were yeasts other than Candida species. The current study, eighteen (18) different types of yeast species were identified from different clinical samples. All recognized yeast considered as a causative agent of fungal infection in previously reported data in worldwide. Conclusion C. albicans remaining the predominant species, but the emergence of non-albicans Candida and other than candida species have increased. Thus, more studies on Candida prevalence are needed throughout country.

scholarly journals Species distribution of yeasts recovered from different clinical samples Addiss Ababa,Ethiopia

2019 ◽  
Author(s):  
Elias Seyoum Deribe ◽  
Adane Bitew ◽  
Amete Mihret
Keyword(s):  
Species Distribution ◽  
Candida Species ◽  
Fungal Infections ◽  
Addis Ababa ◽  
Antifungal Susceptibility ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Clinical Samples ◽  
Cross Sectional ◽  
Reported Data

Abstract Background Currently, fungal diseases of humans are among the most problematic illnesses is the result of an increase in opportunistic fungal infections caused by rise in the number of immune-compromised patients. Particularly, yeasts are the most common cause of fungal infections leading to a range superficial type to life-threatening invasive infections. The aim of this study is to determine species distribution of yeasts particularly of Candida species recovered from different clinical samples. Method A cross sectional study was conducted from January 01, 2018 –September 30, 2018 in Addis Ababa, Arsho laboratory. Oropharengial swabs, nail scrapings, sputum, corneal scrapings, and vaginal swabs were collected from patients with signs and symptoms of infections. Identification and antifungal susceptibility testing was performed by using YST card through VITEK 2 compact system. Data was entered and analyzed using SPSS version 20. Result A total of 209 yeasts were recovered of which 49.8% were Candida albicans, 43.1% were non-albicans candida species and 7.2% were yeasts other than Candida species. The current study, eighteen (18) different types of yeast species were identified from different clinical samples. All recognized yeast considered as a causative agent of fungal infection in previously reported data in worldwide. Conclusion C. albicans remaining the predominant species, but the emergence of non-albicans Candida and other than candida species have increased. Thus, more studies on Candida prevalence are needed throughout country.

scholarly journals The distrubution and antifungal susceptibilities of candida species isolated from clinical samples of intensive care unit patients

2018 ◽  
Vol 10 (2) ◽  
pp. 130-134
Author(s):  
Salih Cesur ◽  
Nilgün Altın ◽  
Göknür Yapar Toros ◽  
Kamer Koldaş ◽  
Gülkan Solgun ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Candida Species ◽  
Clinical Samples
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