Effects of methanol extract of Citrullus lanatus Thunb. (Curcubitaceae) fruit rind on experimentally-induced diarrhoea in Swiss-albino mice

2018 ◽  
Vol 15 (2) ◽  
pp. 117
Author(s):  
Muhajira Ismail ◽  
Bilkisu B. Maiha ◽  
Jamilu Ya’u ◽  
Idris Maje
Keyword(s):  
Methanol Extract ◽  
Citrullus Lanatus ◽  
Swiss Albino Mice ◽  
Albino Mice ◽  
Fruit Rind ◽  
Experimentally Induced

Membrane stabilizing, thrombolytic, analgesic, anti-diarrheal and CNS activities of Polyalthia longifolia (Sonn.)

2014 ◽  
Vol 4 (3) ◽  
pp. 104-109
Author(s):  
Ridwan Islam ◽  
Md. Al Amin Sikder ◽  
Rafeeq Alam Khan ◽  
Mansoor Ahmed ◽  
Mohammad A. Rashid
Keyword(s):  
Analgesic Activity ◽  
Castor Oil ◽  
Methanol Extract ◽  
Bark Extract ◽  
Tail Flick ◽  
Swiss Albino Mice ◽  
Tail Flick Latency ◽  
Albino Mice ◽  
Polyalthia Longifolia ◽  
Crude Methanol Extract

Different fractions of Polialthia longifolia (Sonn.) bark were evaluated for membrane stabilizing, thrombolytic, analgesic, anti-diarrheal and CNS de-pressant activities upon oral administration at 200 and 400 mg/kg body weight. The membrane stabilizing activity was assessed by heat and hypo-tonic solution. Carbon tetrachloride fraction of methanol extract of P. longi-folia bark demonstrated strong membrane stabilizing activity, while the crude methanol extract demonstrated mild to moderate thrombolytic activi-ty in human blood specimen. The analgesic activity was assessed by tail im-mersion and formalin-induced pain method in Swiss-albino mice. The crude methanol extract of P. longifolia bark exhibited significant peripheral and central analgesic activity, since inhibited chemical induced writhing at 200 mg/kg and increased tail flick latency time both at 200 and 400 mg/kg. The anti-diarrheal activity of the bark extract was assessed by using castor oil induced diarrhea in mice however significant anti-diarrheal activity was not revealed. The CNS inhibitory activity of the methanol extract was assessed in Swiss albino mice where it reduced phenobarbitone sodium induced sleep-ing time at 400 mg/kg.

Anticonvulsant Activity of Diospyros cordifolia Bark Against Experimentally Induced Convulsions in Swiss Albino Mice

Pharmacologia ◽  
2012 ◽  
Vol 3 (7) ◽  
pp. 196-199
Author(s):  
Pallab K Haldar ◽  
Sudipta Das ◽  
Sanjib Bhattachar ◽  
Biswakanth Kar ◽  
Goutam Pramanik ◽  
...  
Keyword(s):  
Anticonvulsant Activity ◽  
Swiss Albino Mice ◽  
Albino Mice ◽  
Experimentally Induced

Chemopreventive activity ofWithania somnifera in experimentally induced fibrosarcoma tumours in Swiss albino mice

2001 ◽  
Vol 15 (3) ◽  
pp. 240-244 ◽  
Author(s):  
Jai Prakash ◽  
S. K. Gupta ◽  
V. Kochupillai ◽  
N. Singh ◽  
Y. K. Gupta ◽  
...  
Keyword(s):  
Swiss Albino Mice ◽  
Albino Mice ◽  
Chemopreventive Activity ◽  
Experimentally Induced

scholarly journals Antitumor Activity of Citrus maxima (Burm.) Merr. Leaves in Ehrlich's Ascites Carcinoma Cell-Treated Mice

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Sriparna KunduSen ◽  
Malaya Gupta ◽  
Upal K. Mazumder ◽  
Pallab K. Haldar ◽  
Prerona Saha ◽  
...  
Keyword(s):  
Experimental Design ◽  
Antitumor Activity ◽  
Life Span ◽  
Methanol Extract ◽  
Carcinoma Cell ◽  
Swiss Albino Mice ◽  
Ehrlich’S Ascites Carcinoma ◽  
Citrus Maxima ◽  
Albino Mice

Context. The plant Citrus maxima Merr. (Rutaceae), commonly known as shaddock or pomelo is indigenous to tropical parts of Asia. The objective of present study is to evaluate the methanol extract of Citrus maxima leaves for its antitumor activity against Ehrlich's Ascites Carcinoma cell in Swiss albino mice. Experimental design. The antitumor activity of methanol extract of Citrus maxima leaves (MECM) was evaluated against Ehrlich Ascites Carcinoma (EAC) cell line in Swiss albino mice. 2 × 106 cells were inoculated in different groups of animals. MECM (200 and 400 mg/kg BW i.p.) was administered for nine consecutive days. On day 10th half the animals of different groups were sacrificed for determination of tumor and haematological parameters and the rest half were kept with sufficient food and water ad libitum for determination of increase in life span. Result and Discussions. Oral administration of the extract at the doses of 200 and 400 mg/kg significantly decreased tumor parameters such as tumor volume, viable tumor cell count and increased body weight, hematological parameters and life span in respect of the EAC control mice. Conclusion. Experimental design exhibits significant antitumor activity of the extract (MECM) in a dose dependant manner.

Evaluation of anti-cancer activity of Tinospora cordifolia on experimentally induced spontaneous fibrosarcoma in Swiss albino mice

2021 ◽  
Vol 45 (1) ◽  
pp. 15-23
Author(s):  
Noopur Halmare ◽  
P.P. Gaonkar ◽  
P.M. Sonkusale ◽  
A.P. Somkuwar ◽  
A.D. Ingle ◽  
...  
Keyword(s):  
Tinospora Cordifolia ◽  
Swiss Albino Mice ◽  
Anti Cancer ◽  
Albino Mice ◽  
Cancer Activity ◽  
Experimentally Induced
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