scholarly journals Thyroid function in multidrug-resistant tuberculosis patients with or without human immunodeficiency virus (HIV) infection before commencement of MDR-TB drug regimen

2016 ◽  
Vol 16 (2) ◽  
pp. 596 ◽  
Author(s):  
Olusoji Mayowa Ige ◽  
Kehinde Sola Akinlade ◽  
Sheu Kadiri Rahamon ◽  
Victory Fabian Edem ◽  
Olatunbosun Ganiyu Arinola
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hiv Infection ◽  
Thyroid Function ◽  
Drug Regimen ◽  
Multidrug Resistant ◽  
Tuberculosis Patients ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Immunodeficiency Virus ◽  
Mdr Tb

scholarly journals Scrofula Caused by Multidrug-Resistant Tuberculosis

2020 ◽  
Author(s):  
Bárbara Pedro ◽  
Liliana Alves ◽  
Rita Magano ◽  
Tomás Nunes ◽  
Nuno Marques
Keyword(s):  
Human Immunodeficiency Virus ◽  
Mycobacterium Tuberculosis ◽  
Causes Of Death ◽  
Cervical Lymphadenopathy ◽  
Multidrug Resistant ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Immunodeficiency Virus ◽  
Mdr Tb ◽  
Hiv Negative

Tuberculosis (TB) is one of the top 10 causes of death worldwide. Multidrug-resistant tuberculosis (MDR-TB) occurs when at the minimum there is resistance to isoniazid and rifampin. Prevention of new infections of Mycobacterium tuberculosis and progression to TB disease is critical to reduce the burden and mortality of this disease. We present the case of a 73-year-old human immunodeficiency virus (HIV)-negative female who presented with cervical lymphadenopathy and who was diagnosed with MDR-TB.

scholarly journals Outcome of Multidrug-Resistant Tuberculosis in Human Immunodeficiency Virus-Infected Patients

1999 ◽  
Vol 29 (3) ◽  
pp. 553-560 ◽  
Author(s):  
Fabio Franzetti ◽  
Andrea Gori ◽  
Enrico Iemoli ◽  
Paola Meraviglia ◽  
Franco Mainini ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Multidrug Resistant ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Immunodeficiency Virus

scholarly journals Analysis of Smear Microscopy and Culture Conversion Results in Multidrug-Resistant Tuberculosis Patients with and without Type 2 Diabetes Mellitus

2020 ◽  
Vol 26 (3) ◽  
Author(s):  
Henny Fauziah ◽  
Aprianti S. ◽  
Handayani I. ◽  
Kadir NA
Keyword(s):  
Diabetes Mellitus ◽  
Multidrug Resistant ◽  
World Health ◽  
Smear Microscopy ◽  
Tuberculosis Patients ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Significant Difference ◽  
Mdr Tb ◽  
Culture Conversion

  The World Health Organization (WHO) recommended microscopic AFB smear examination and culture as follow-ups to the response of MDR TB therapy. Analyzed the results of microscopic AFB smear and culture conversion as well as treatment outcome in Multidrug-Resistant Tuberculosis (MDR-TB) patients with and without Diabetes Mellitus (DM). This is a retrospective study involved 70 MDR-TB patients with (27 patients) with DM and without DM (43 patients) who had microscopic AFB smear and culture results at the start of the follow-up therapy. This research was conducted at Labuang Baji Regional Public Hospital, Makassar, from June to July 2019, used medical records of MDR-TB patients the period of June 2016 to December 2017. The results showed that 52 out of 70 MDR-TB patients had microscopic AFB smear and culture conversion in MDR-TB with DM (21 patients) and without DM (31 patients). The duration of microscopic AFB smear conversion in MDR TB patients with DM (3.33±0.54 months) was longer than patients without DM (2.07±0.05 months), p=0.001. While in culture conversion, there was no significant difference between MDR-TB with DM (1.28±0.64 months) and without DM (1.25±0.59), p=0.648. The recovery outcome between MDR-TB with (48.1%) and without DM (48.8%) was not significantly different. However, the output of treatment failure was greater in DM (11.2%) than without DM (2.3%), although statistically, there was no significant difference (p=0.568). Multidrug-resistant tuberculosis patients with DM experienced slower microscopic AFB smear conversion than MDR-TB patients without DM. However, in culture, there was no significant difference in the conversion period between the two groups. MDR-TB patients, both of with and without DM, had the same chance of recovery.

scholarly journals Impact of HIV co-infection on the evolution and transmission of multidrug-resistant tuberculosis

eLife ◽  
2016 ◽  
Vol 5 ◽  
Author(s):  
Vegard Eldholm ◽  
Adrien Rieux ◽  
Johana Monteserin ◽  
Julia Montana Lopez ◽  
Domingo Palmero ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Multidrug Resistant ◽  
Transmission Networks ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Hiv Epidemic ◽  
Immunodeficiency Virus ◽  
Resistant Strains ◽  
The Impact ◽  
Emergence Of Resistance

The tuberculosis (TB) epidemic is fueled by a parallel Human Immunodeficiency Virus (HIV) epidemic, but it remains unclear to what extent the HIV epidemic has been a driver for drug resistance in Mycobacterium tuberculosis (Mtb). Here we assess the impact of HIV co-infection on the emergence of resistance and transmission of Mtb in the largest outbreak of multidrug-resistant TB in South America to date. By combining Bayesian evolutionary analyses and the reconstruction of transmission networks utilizing a new model optimized for TB, we find that HIV co-infection does not significantly affect the transmissibility or the mutation rate of Mtb within patients and was not associated with increased emergence of resistance within patients. Our results indicate that the HIV epidemic serves as an amplifier of TB outbreaks by providing a reservoir of susceptible hosts, but that HIV co-infection is not a direct driver for the emergence and transmission of resistant strains.

Sign in / Sign up

Export Citation Format

Share Document