Review Of Interventions To Prevent Mother –To- Child Transmission And Seroprevalence Of Hiv Infection Among Paturients Advent To The Era Of Antiretroviral Therapy In Nigeria- Experienec From A Mission Hospital In Benin City, Nigeria

2008 ◽  
Vol 6 (2) ◽  
Author(s):  
JUE Onakewhor ◽  
O Emasealu
2010 ◽  
Vol 2 (2) ◽  
pp. 58-61 ◽  
Author(s):  
Paul Erhunmwunse Imade ◽  
Nkemjika Obiageri Uwakwe ◽  
Richard Omoregie ◽  
Nosakhare Odeh Eghafona

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0260941
Author(s):  
Dulce Osório ◽  
Isabelle Munyangaju ◽  
Edy Nacarapa ◽  
Argentina Muhiwa ◽  
Amancio Vicente Nhangave ◽  
...  

Background Mother-to-child transmission of HIV infection is a significant problem in Mozambique. This study aims to determine the risk factors associated with mother-to-child transmission of HIV in rural Mozambique. Methods Retrospective case-control study in a rural area of Bilene District, on the coast of southern Mozambique, performed from January 2017 to June 2018. The analysis considered the clinical data of HIV exposed children with definitive HIV positive results and their respective infected mothers (cases), and the data of HIV exposed children with definitive HIV negative results and their respective infected mothers (controls) registered in At Risk Child Clinics from 1st January 2017 to 30th June 2018 at the Macia and Praia de Bilene health facilities in Bilene district, Gaza province–Mozambique. Results Ninety pregnant women with HIV were involved in the study, including 30 who had transmitted the infection to their children and 60 who had not. Statistical analysis, adjusted for maternal age and gestational age at first antenatal care visit, showed that independent risk factors for transmission were gestational age at first visit (adjusted odds ratio [aOR] 1.19, 95% confidence interval [CI] 1.05–1.36), non-adherence to combination antiretroviral therapy (56.7% vs. 5%; aOR 14.12, 95% CI 3.15–63.41); a viral load of 1000 copies/mL or more (90% vs. 5%; aOR: 156, 95% CI 22.91–1,062) and female sex of the neonate (80% vs. 51.7%; aOR: 4.43, 95% CI 1.33–15.87). Conclusion A high viral load and non-adherence to antiretroviral therapy are important predictors of mother-to-child HIV transmission.


Author(s):  
Karin Nielsen-Saines

Upon completion of this chapter, the reader should be able to • Understand the basics regarding pathogenesis of mother to child HIV transmission (MTCT) and be aware of landmark studies targeting prevention of HIV mother to child transmission (PMTCT). • Understand the concept of HIV-exposure versus HIV-infection....


2004 ◽  
Vol 23 (1) ◽  
pp. 15-20
Author(s):  
Anne Katz

The purpose of this article is to describe the pertinent issues related to mother-to-child transmission of HIV infection. Significant success has been achieved in developed countries to reduce the incidence of this devastating disease in neonates through screening of pregnant women, maternal antiretroviral therapy to reduce transmission, and cesarean section for delivery. Prophylaxis continues for the first six weeks of the newborn’s life with antiretroviral therapy and careful monitoring of clinical well-being. Antiretroviral therapy offers significant reduction in the rate of mother-to-child transmission, and this is presently the cornerstone of therapy for the HIV-infected pregnant woman. Clinical studies of treatment modalities continue to offer new hope to prevent transmission of the virus to the fetus. Care for the HIV-infected newborn is highly complex and constantly evolving. All neonatal nurses should be aware of these issues so that they can be partners in the identification of new cases and the ongoing treatment of babies who are infected.


Author(s):  
Chandrashekhara Chandrashekhara ◽  
Sandeepkumar O

Children are innocent victims of HIV infection through vertical transmission. Children who are HIV positive, either through mother-to-child transmission or following sexual abuse, are often not told what could happen to them, and they will certainly be frightened when they experience symptoms.


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