Experimental study on two-way application of traditional Chinese medicines capable of promoting blood circulation and removing blood stasis with neutral property in cold and hot blood stasis syndrome I

2012 ◽  
Author(s):  
HAO Er-wei
Keyword(s):  
Experimental Study ◽  
Blood Circulation ◽  
Blood Stasis ◽  
Blood Stasis Syndrome ◽  
Traditional Chinese Medicines ◽  
Chinese Medicines

scholarly journals Chinese Herb and Formulas for Promoting Blood Circulation and Removing Blood Stasis and Antiplatelet Therapies

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Yue Liu ◽  
Hui-Jun Yin ◽  
Da-zhuo Shi ◽  
Ke-ji Chen
Keyword(s):  
Acute Coronary Syndromes ◽  
Blood Circulation ◽  
Adverse Reactions ◽  
Chinese Herb ◽  
Blood Stasis ◽  
Bleeding Risk ◽  
Blood Stasis Syndrome ◽  
The World ◽  
Close Relationship ◽  
Coronary Syndromes

Atherothrombosis, which directly threatens people's health and lives, is the main cause of morbidity and mortality all over the world. Platelets play a key role in the development of acute coronary syndromes (ACSs) and contribute to cardiovascular events. Oral antiplatelet drugs are a milestone in the therapy of cardiovascular atherothrombotic diseases. In recent years, many reports have shown the possibility that “resistance” to oral anti-platelet drugs and many adverse reactions, such as serious bleeding risk, which provides an impetus for developing new anti-platelet drugs possesses highly efficiency and fewer adverse effects. Study on the blood stasis syndrome and promoting blood circulation and removing blood stasis is the most active field of research of integration of traditional and western medicine in China. Blood-stasis syndrome and platelet activation have close relationship, many Chinese herb and formulas for promoting blood circulation and removing blood stasis possess definite anti-platelet effect. This paper covers the progress of anti-platelet mechanism of Chinese herb and formulas for promoting blood circulation and removing blood stasis and is to be deeply discussed in further research.

scholarly journals The Mechanism Research of Qishen Yiqi Formula by Module-Network Analysis

2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Shichao Zheng ◽  
Yanling Zhang ◽  
Yanjiang Qiao
Keyword(s):  
Protein Interactions ◽  
Blood Circulation ◽  
Blood Stasis ◽  
Interaction Network ◽  
Enrichment Analysis ◽  
Small World ◽  
Blood Stasis Syndrome ◽  
Active Components ◽  
Scale Free ◽  
Topological Parameters

Qishen Yiqi formula (QSYQ) has the effect of tonifying Qi and promoting blood circulation, which is widely used to treat the cardiovascular diseases with Qi deficiency and blood stasis syndrome. However, the mechanism of QSYQ to tonify Qi and promote blood circulation is rarely reported at molecular or systems level. This study aimed to elucidate the mechanism of QSYQ based on the protein interaction network (PIN) analysis. The targets’ information of the active components was obtained from ChEMBL and STITCH databases and was further used to search against protein-protein interactions by String database. Next, the PINs of QSYQ were constructed by Cytoscape and were analyzed by gene ontology enrichment analysis based on Markov Cluster algorithm. Finally, based on the topological parameters, the properties of scale-free, small world, and modularity of the QSYQ’s PINs were analyzed. And based on function modules, the mechanism of QSYQ was elucidated. The results indicated that Qi-tonifying efficacy of QSYQ may be partly attributed to the regulation of amino acid metabolism, carbohydrate metabolism, lipid metabolism, and cAMP metabolism, while QSYQ improves the blood stasis through the regulation of blood coagulation and cardiac muscle contraction. Meanwhile, the “synergy” of formula compatibility was also illuminated.

Experimental Study on the Relationship between Tongue Temperature and the Lingual Circulatory System

2013 ◽  
Vol 321-324 ◽  
pp. 708-711
Author(s):  
Hai Wei Xie ◽  
Yan Zhang
Keyword(s):  
Experimental Study ◽  
Animal Model ◽  
Blood Flow ◽  
Blood Stasis ◽  
Circulatory System ◽  
Blood Flow Rate ◽  
Deficiency Syndrome ◽  
Blood Stasis Syndrome ◽  
Vascular Cast ◽  
The Relationship

To study the relationship between tongue temperature and the lingual circulatory system, the blood stasis and blood deficiency syndrome of traditional Chinese medicine (TCM) syndromes were researched by making animal model and vascular cast experiment. The influence of blood stasis and blood deficiency syndrome on tongue temperature and the lingual circulatory system were studied and analyzed. The experimental results indicated that the lingual circulatory system of blood stasis syndrome and that of blood deficiency syndrome were distinctly different in blood flow rate, vascular diameters and the density of small vessel. These differences in circulatory system could induce a change on lingual temperature. This result proves that the tongue temperature has relations with the change of lingual circulatory system.

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