scholarly journals Research Article Selection of genomic regions and genes associated with adaptation and fertility traits in two Colombian creole cattle breeds

2021 ◽  
Vol 20 (3) ◽  
Author(s):  
C. De León ◽  
R. Martínez ◽  
J.F. Rocha ◽  
A.E. Darghan
Keyword(s):  
Cattle Breeds ◽  
Research Article ◽  
Creole Cattle ◽  
Genomic Regions ◽  
Fertility Traits ◽  
Selection Of

scholarly journals Mapping QTL for spike fertility and related traits in two doubled haploid wheat (Triticum aestivum L.) populations

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nicole Pretini ◽  
Leonardo S. Vanzetti ◽  
Ignacio I. Terrile ◽  
Guillermo Donaire ◽  
Fernanda G. González
Keyword(s):  
Doubled Haploid ◽  
Marker Assisted Selection ◽  
Triticum Aestivum L ◽  
Physiological Model ◽  
Yield Potential ◽  
Breeding Programs ◽  
Per Se ◽  
Genomic Regions ◽  
Fertility Traits ◽  
Selection Of

Abstract Background In breeding programs, the selection of cultivars with the highest yield potential consisted in the selection of the yield per se, which resulted in cultivars with higher grains per spike (GN) and occasionally increased grain weight (GW) (main numerical components of the yield). In this study, quantitative trait loci (QTL) for GW, GN and spike fertility traits related to GN determination were mapped using two doubled haploid (DH) populations (Baguette Premium 11 × BioINTA 2002 and Baguette 19 × BioINTA 2002). Results In total 305 QTL were identified for 14 traits, out of which 12 QTL were identified in more than three environments and explained more than 10% of the phenotypic variation in at least one environment. Eight hotspot regions were detected on chromosomes 1A, 2B, 3A, 5A, 5B, 7A and 7B in which at least two major and stable QTL sheared confidence intervals. QTL on two of these regions (R5A.1 and R5A.2) have previously been described, but the other six regions are novel. Conclusions Based on the pleiotropic analysis within a robust physiological model we conclude that two hotspot genomic regions (R5A.1 and R5A.2) together with the QGW.perg-6B are of high relevance to be used in marker assisted selection in order to improve the spike yield potential. All the QTL identified for the spike related traits are the first step to search for their candidate genes, which will allow their better manipulation in the future.

scholarly journals RELATIONSHIP OF SKIN MEASUREMENTS AND MILK PRODUCTION LEVELS IN CATTLE BREEDS MAINTAINED IN THE TROPICS

2021 ◽  
Vol 4 (2) ◽  
pp. 92-95
Author(s):  
S. F. Amakiri
Keyword(s):  
Hair Follicle ◽  
Milk Production ◽  
Skin Thickness ◽  
Production Potential ◽  
Cattle Breeds ◽  
Positive Linear Correlation ◽  
The Tropics ◽  
Relationship Of ◽  
The Relationship ◽  
Selection Of

The relationship between mean skin thickness or hair follicle depth of the skin from the midside (12th rib) area and milk production levels of pure Friesian (Holstein)cattle breeds, their ¾ and 7/8 crosses with White Fulani zebu, and pure White Fulanis, maintained in South-Western Nigeria were studied. A strongly positive linear correlation (r = 0.9), significant at 1% level was found between skin thickness and hair follicle depth, and milk production levels in these breeds. The results indicate that for cows maintained in a hot humid tropical environment, comparative midside skin thickness and hair follicle depth could be used as indices of the milk production potential of cows. It could be a useful field tool for selection of cows for milk production when considered along with other characteristics

scholarly journals Literary runaway: Increasingly more references cited per academic research article from 1980 to 2019

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255849
Author(s):  
Can Dai ◽  
Quan Chen ◽  
Tao Wan ◽  
Fan Liu ◽  
Yanbing Gong ◽  
...  
Keyword(s):  
Linear Growth ◽  
Academic Research ◽  
Research Papers ◽  
General Increase ◽  
Know How ◽  
Research Article ◽  
Academic Publications ◽  
Digitized Documents ◽  
Number Of Publications ◽  
Selection Of

References are employed in most academic research papers to give credits and to reflect scholarliness. With the upsurge in academic publications in recent decades, we are curious to know how the number of references cited per research article has changed across different disciplines over that time. The results of our study showed significant linear growth in reference density in eight disciplinary categories between 1980 and 2019 indexed in Web of Science. It appears that reference saturation is not yet in sight. Overall, the general increase in the number of publications and the advanced accessibility of the Internet and digitized documents may have promoted the growth in references in certain fields. However, the seemingly runaway tendency should be well appreciated and objectively assessed. We suggest that authors focus on their research itself rather than on political considerations during the process of writing, especially the selection of important references to cite.

The genetic and RFLP characterization of the left end of linkage group III in Caenorhabditis elegans

Genome ◽  
1993 ◽  
Vol 36 (4) ◽  
pp. 712-724 ◽  
Author(s):  
Dave Pilgrim
Keyword(s):  
Caenorhabditis Elegans ◽  
Linkage Group ◽  
Genetic Map ◽  
Physical Map ◽  
Group Iii ◽  
C Elegans ◽  
Genomic Regions ◽  
Caenorhabditis Elegans Genome ◽  
Selection Of

A genetic approach was taken to identify new transposable element Tc1 -dependent polymorphisms on the left end of linkage group III in the nematode Caenorhabditis elegans. The cloning of the genomic DNA surrounding the Tc1 allowed the selection of overlapping clones (from the collection being used to assemble the physical map of the C. elegans genome). A contig of approximately 600–800 kbp in the region has been identified, the genetic map of the region has been refined, and 10 new RFLPs as well as at least four previously characterized genetic loci have been positioned onto the physical map, to the resolution of a few cosmids. This analysis demonstrated the ability to combine physical and genetic mapping for the rapid analysis of large genomic regions (0.5–1 Mbp) in genetically amenable eukaryotes.Key words: Caenorhabditis elegans, genome analysis, RFLP, physical map, genetic map.

132 OVERVIEW OF FERTILITY TRAITS IN RUSSIAN HOLSTEIN BULLS USING GENOME-WIDE ASSOCIATION

2017 ◽  
Vol 29 (1) ◽  
pp. 174 ◽  
Author(s):  
A. A. Sermyagin ◽  
E. N. Naryshkina ◽  
E. A. Gladyr ◽  
I. N. Yanchukov ◽  
G. Brem ◽  
...  
Keyword(s):  
Semen Quality ◽  
Additive Genetic Variance ◽  
Sperm Concentration ◽  
Cattle Breed ◽  
Ministry Of Education ◽  
Data Set ◽  
Scientific Organizations ◽  
Estimated Breeding Values ◽  
Genomic Regions ◽  
Fertility Traits

Holsteins are the most widely distributed cattle breed in Russia. To achieve improvement of both milk production and fertility traits, principles were elaborated to use genomic approaches together with breeding strategies to develop a common breeding index. Combining semen-quality measures for sires with the cows’ reproduction records makes it possible to resolve the problems with decreased conception rates and semen production. Our objective was to search the genomic regions and associated markers for bulls’ fertility traits in Russian Holstein cattle. For the first step, 282 bulls were genotyped using the Bovine SNP50 BeadChip (Illumina Inc., San Diego, CA, USA). The data set originated from the Moscow AI station including records for semen volume (SV), sperm concentration (SC), average SV for multiple ejaculates collected from one sire (ASV), motility (Mt), and number of spermatozoa (NS). The data set consisted of 14,490 records, which varied between 10 and 328 per animal, with 104 sires in the data set. The average age of sires was 80.1 ± 0.3 months. For sires with own records, the deregressed estimated breeding values were calculated using BLUP AM, whereas for the sires without records direct genomic values (DGV) were calculated through GBLUP. The DGV values were used as the animal’s pseudo-phenotypes for a common data set. After quality check in Plink 1.07, 41,435 SNP were taken. Bonferroni correction test for detection of significant associations was applied as P < 1.21 × 10−6. The values for the heritability were 0.322, 0.202, 0.366, 0.014, and 0.169 for SV, SC, ASV, Mt, and NS, respectively. The SNP with a direct significant effect on SV and ASV were identified: ARS-BFGL-NGS-100206 (P = 1.5 × 10−7), BTA-89872-no-rs (P = 6.0 × 10−8), ARS-BFGL-NGS-33119 (P = 2.7 × 10−7), Hapmap26947-BTA-133787 (P = 5.0 × 10−7), BTA-30092-no-rs (P = 9.8 × 10−7), ARS-BFGL-BAC-6515 (P = 1.0 × 10−7), and BTB-01625220 (P = 4.2 × 10−8). For SC and NS traits, the polymorphisms ARS-BFGL-NGS-57433 (P = 7.4 × 10−7) and ARS-BFGL-NGS-12662 (P = 5.1 × 10−7) were found. Two QTL for Mt including 11 SNP were detected on BTA1 (146.3–146.9 Mb) and BTA9 (76.9–77.1 Mb). The DGV effect of SNP (R2) ranged from 8.0 to 10.4% of additive genetic variance. The genes SOX5 (BTA12), PERP (BTA9), and EPT1 (BTA11) were associated with embryonic development, cell death, or apoptosis and synthesis of selenoproteins. Our results may be used to select donor cows for oocytes or embryo collection in the focus of genomic selection. Supported by the Federal Agency for Scientific Organizations #0600–2014–0007.6 and by the Russian Ministry of Education and Science #RFMEFI60414X0062.

‘Ideal-Problem-Solution’ (IPS) Model

2011 ◽  
Vol 34 (1) ◽  
pp. 75-103 ◽  
Author(s):  
Zifirdaus Adnan
Keyword(s):  
Significant Role ◽  
Discourse Structure ◽  
Problem Solution ◽  
New Model ◽  
Research Article ◽  
Discourse Patterns ◽  
Ips Model ◽  
Selection Of ◽  
Model Fits

Research article introductions (RAIs) play a significant role in gaining publication, and therefore have been studied by many applied linguists. Research into RAIs published in Indonesia has begun to be developed (Adnan, 2009; Mirahayuni, 2001; Safnil, 2000), and generally conclude that Indonesian Humanities RAIs were structured differently from English RAIs. However, as these are early studies, their findings still awaits scrutiny, and little information on Indonesian RAIs especially in Education has been published. Several models describing discourse structure of research article introductions have been proposed, but they have been problematic when applied to analyse RAIs. This paper reports an examination of the applicability of two important models, the CARS (Swales, 1990) and the PJP model claimed to be an Indonesian model of Humanities RAIs (Safnil, 2000), using a selection of 21 Indonesian research article Introductions (RAIs) written by Indonesian academics in Education. It concentrates on the following questions: To what extent do these models fit the data and why? The examination found that none of the RAIs fit the CARS, and only less than half fit the PJP model for various reasons. Therefore a new model is proposed. This model fits most of the data. The paper claims that apart from national concerns, discourse patterns of RAIs are also affected by writing guides provided by the discipline.

scholarly journals Parallel Seed Color Adaptation during Multiple Domestication Attempts of an Ancient New World Grain

2019 ◽  
Vol 37 (5) ◽  
pp. 1407-1419 ◽  
Author(s):  
Markus G Stetter ◽  
Mireia Vidal-Villarejo ◽  
Karl J Schmid
Keyword(s):  
Genomic Region ◽  
Color Variation ◽  
Chromosome 9 ◽  
Seed Color ◽  
Color Adaptation ◽  
Crop Species ◽  
Grain Amaranth ◽  
Amaranth Species ◽  
Genomic Regions ◽  
Selection Of

Abstract Thousands of plants have been selected as crops; yet, only a few are fully domesticated. The lack of adaptation to agroecological environments of many crop plants with few characteristic domestication traits potentially has genetic causes. Here, we investigate the incomplete domestication of an ancient grain from the Americas, amaranth. Although three grain amaranth species have been cultivated as crop for millennia, all three lack key domestication traits. We sequenced 121 crop and wild individuals to investigate the genomic signature of repeated incomplete adaptation. Our analysis shows that grain amaranth has been domesticated three times from a single wild ancestor. One trait that has been selected during domestication in all three grain species is the seed color, which changed from dark seeds to white seeds. We were able to map the genetic control of the seed color adaptation to two genomic regions on chromosomes 3 and 9, employing three independent mapping populations. Within the locus on chromosome 9, we identify an MYB-like transcription factor gene, a known regulator for seed color variation in other plant species. We identify a soft selective sweep in this genomic region in one of the crop species but not in the other two species. The demographic analysis of wild and domesticated amaranths revealed a population bottleneck predating the domestication of grain amaranth. Our results indicate that a reduced level of ancestral genetic variation did not prevent the selection of traits with a simple genetic architecture but may have limited the adaptation of complex domestication traits.

scholarly journals Genome-Wide Association Study of Body Weight Traits in Chinese Fine-Wool Sheep

Animals ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 170 ◽  
Author(s):  
Zengkui Lu ◽  
Yaojing Yue ◽  
Chao Yuan ◽  
Jianbin Liu ◽  
Zhiqiang Chen ◽  
...  
Keyword(s):  
Body Weight ◽  
Muscle Development ◽  
Genome Wide Association Study ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Genome Wide ◽  
Economic Trait ◽  
Significance Levels ◽  
Genomic Regions ◽  
Selection Of

Body weight is an important economic trait for sheep and it is vital for their successful production and breeding. Therefore, identifying the genomic regions and biological pathways that contribute to understanding variability in body weight traits is significant for selection purposes. In this study, the genome-wide associations of birth, weaning, yearling, and adult weights of 460 fine-wool sheep were determined using resequencing technology. The results showed that 113 single nucleotide polymorphisms (SNPs) reached the genome-wide significance levels for the four body weight traits and 30 genes were annotated effectively, including AADACL3, VGF, NPC1, and SERPINA12. The genes annotated by these SNPs significantly enriched 78 gene ontology terms and 25 signaling pathways, and were found to mainly participate in skeletal muscle development and lipid metabolism. These genes can be used as candidate genes for body weight in sheep, and provide useful information for the production and genomic selection of Chinese fine-wool sheep.

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