scholarly journals Sequence variants in the bovine PRDM16 gene associated with body weight in Chinese cattle breeds

2012 ◽  
Vol 11 (1) ◽  
pp. 746-755 ◽  
Author(s):  
J. Wang ◽  
C. Wang ◽  
R. Tian ◽  
Y.-Z. Huang ◽  
X.-S. Lai ◽  
...  
Keyword(s):  
Body Weight ◽  
Sequence Variants ◽  
Cattle Breeds ◽  
Chinese Cattle ◽  
Prdm16 Gene

Sequence variants in the bovine nucleophosmin 1 gene, their linkage and their associations with body weight in native cattle breeds in China

2011 ◽  
Vol 42 (5) ◽  
pp. 556-559 ◽  
Author(s):  
Y. Z. Huang ◽  
H. He ◽  
J. Wang ◽  
Z. J. Li ◽  
X. Y. Lan ◽  
...  
Keyword(s):  
Body Weight ◽  
Sequence Variants ◽  
Cattle Breeds ◽  
Native Cattle

scholarly journals Genetic variations of the bovine MX1 and their association with mastitis

2017 ◽  
Vol 62 (No. 4) ◽  
pp. 157-167
Author(s):  
N. Chen ◽  
F. Wang ◽  
N. Yu ◽  
Y. Gao ◽  
J. Huang ◽  
...  
Keyword(s):  
Dairy Cattle ◽  
Wide Spectrum ◽  
Holstein Cows ◽  
Holstein Cattle ◽  
Nucleotide Polymorphisms ◽  
Coding Region ◽  
Bacterial Strains ◽  
Cattle Breeds ◽  
Chinese Cattle ◽  
Mx1 Gene

The primary agent of mastitis is a wide spectrum of bacterial strains; however, viral-related mastitis has also been reported. The MX dynamin-like GTPase 1 (MX1) gene has been demonstrated to confer positive antiviral responses to many viruses, and may be a suitable candidate gene for the study of disease resistance in dairy cattle. The present study was conducted to investigate the genetic diversity of the MX1 gene in Chinese cattle breeds and its effects on mastitis in Holstein cows. First, polymorphisms were identified in the complete coding region of the bovine MX1 gene in 14 Chinese cattle breeds. An association study was then carried out, utilizing polymorphisms detected in Holstein cows to determine the associations of these single nucleotide polymorphisms (SNPs) with mastitis. We identified 13 previously reported SNPs in Chinese domestic cattle and four of them in Holstein cattle. A novel 12 bp indel was also discovered in Holstein cattle. In addition, haplotype frequencies and linkage disequilibrium of four SNPs detected in Holstein cows were investigated. Analysis of these four SNPs in Chinese Holstein cows revealed two SNPs (g.143181370 T&gt;C and g.143182088 C&gt;T)<br /> significantly (P &lt; 0.05) associated with somatic cell score (SCS). The results indicated that SNPs in the MX1 gene might contribute to the variations observed in the SCS of dairy cattle. Therefore, implementation of these two mutations in selection indexes of the dairy industry might be beneficial by favouring the selection individuals with lower SCS.

scholarly journals Morphology of small intestinal mucosa and intestinal weight change with metabolic type of cattle

2008 ◽  
Vol 53 (No. 10) ◽  
pp. 525-532 ◽  
Author(s):  
R. Zitnan ◽  
J. Voigt ◽  
S. Kuhla ◽  
J. Wegner ◽  
A. Chudy ◽  
...  
Keyword(s):  
Body Weight ◽  
Small Intestine ◽  
Intestinal Mucosa ◽  
High Energy ◽  
Proximal Jejunum ◽  
Small Intestinal Mucosa ◽  
Apparent Digestibility ◽  
Cattle Breeds ◽  
Metabolic Type ◽  
Small Intestinal

The objective of this study was to investigate rumen fermentation, apparent digestibility of nutrients, and morphology of ruminal und intestinal mucosa in two cattle breeds of different metabolic type. From each breed six purebred German Holstein (H) bulls representing the secretion type and six Charolais (CH) bulls representing the accretion type were raised and fattened under identical conditions with <I>semi ad libitum</I> feeding of a high energy diet. The animals were used for a digestion trial started at nine months of age and animals were slaughtered at 18 months of age. Body weight (668 vs. 764 kg, <I>P</I> = 0.011), body weight gain (1 223 vs. 1 385 g/day, <I>P</I> = 0.043), and body protein gain (93 vs. 128 g/day, <I>P</I> = 0.001) were lower in H compared to CH bulls. Protein expense per kg protein accretion was higher in H bulls (13.8 vs. 10.2, <I>P</I> = 0.001). No significant differences were found in concentration and pattern of ruminal short chain fatty acid and in apparent digestibility of organic matter, crude fibre, and N-free extracts. There were no significant differencs in all morphometric traits of rumen mucosa between both cattle breeds. Compared to H, the villi of CH bulls were higher in duodenum (586 vs. 495 &mu;m, <I>P</I> = 0.001) and proximal jejunum (598 vs. 518&mu;m, <I>P</I> < 0.001), the crypt were deeper in duodenum (295 vs. 358, <I>P</I>< 0.001) and proximal jejunum (292 vs. 344 &mu;m, <I>P</I> = 0.020). In contrast, the villi in ileum were higher in H (522 vs. 471 &mu;m, <I>P</I> = 0.006). The weight of total small intestine, as percentage of total body weight, was 1.1 in H and 0.8 in CH (<I>P</I> = 0.002). The utilization of food crude protein was positively related to the duodenal (<I>P</I> = 0.001) and proximal jejunal villus height (<I>P</I> = 0.003) and to the duodenal crypt depth (<I>P</I> < 0.001) and negatively related to weight of small intestine (<I>P</I> = 0.004). It is concluded, that the higher growth potential and feed efficiency in CH bulls compared to H bulls is not caused by differences in digestion processes, but in size of small intestine, and morphology of small intestinal mucosa. Obviously the duodenum and proximal jejunum of CH bulls adapt to increase the absorptive surface due to the increase in nutrient demand.

A 5′UTR SNP of GHRHR locus is associated with body weight and average daily gain in Chinese cattle

2012 ◽  
Vol 39 (12) ◽  
pp. 10469-10473 ◽  
Author(s):  
C. F. Zhang ◽  
H. Chen ◽  
Z. Y. Zhang ◽  
L. Z. Zhang ◽  
D. Y. Yang ◽  
...  
Keyword(s):  
Body Weight ◽  
Average Daily Gain ◽  
Chinese Cattle ◽  
Daily Gain

Two novel intronic polymorphisms of bovine FGF21 gene are associated with body weight at 18 months in Chinese cattle

2013 ◽  
Vol 155 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Xiao-Mei Sun ◽  
Ming-Xun Li ◽  
Ai-Min Li ◽  
Xian-Yong Lan ◽  
Chu-Zhao Lei ◽  
...  
Keyword(s):  
Body Weight ◽  
Chinese Cattle

Development of valuation index for draught cattle breeds of Tamil Nadu, India

2015 ◽  
Author(s):  
N. K. Sudeep Kumar ◽  
P. R. Nisha ◽  
S. Senthil Kumar ◽  
G. Senthil Kumar
Keyword(s):  
Body Weight ◽  
Tamil Nadu ◽  
Negative Influence ◽  
Mean Value ◽  
Body Region ◽  
Personal Interview ◽  
Interview Schedule ◽  
Cattle Breeds ◽  
Cent Level ◽  
The Right

An attempt was made to develop a valuation index for draught cattle breeds of Tamil Nadu, which would help the farmers in getting the right price for their animals sold. The data were collected through personal interview using pre-tested interview schedule from 225 draught cattle owners from selected three districts of Tamil Nadu during the year 2010-11. A multiple linear regression was fitted for arriving at the valuation index of draught cattle breeds viz., Burgur, Kangayam and Umbalacherry. The adjusted R2 for overall draught cow valuation index was 0.818. The factors like presence of whirls in acceptable body region, skin and coat, body weight, milk yield and presence of pregnancy were found to be significant and had influenced the value of animal to the tune of Rs. 1642.40, Rs.1250.21, Rs. 36.25, Rs. 679.30 and Rs. 1241.24, respectively from their mean value. The overall draught bullock valuation index was also fitted and its adjusted R2 was 0.428. The variable body weight was found to be significant at one per cent level, whereas age was found to be significant at five per cent level and had negative influence on bullock value. The duration of work was found to be significant at five per cent level and it hiked the value at the rate of Rs.528.26. The variables like skin and coat, activeness, whirls, right pair, disease tolerance and breed were found to be non-significant.

scholarly journals Association between Polymorphisms of MSTN and MYF5 Genes and Growth Traits in Three Chinese Cattle Breeds

2007 ◽  
Vol 20 (12) ◽  
pp. 1798-1804 ◽  
Author(s):  
R. F. Zhang ◽  
H. Chen ◽  
C. Z. Lei ◽  
C. L. Zhang ◽  
X. Y. Lan ◽  
...  
Keyword(s):  
Growth Traits ◽  
Cattle Breeds ◽  
Chinese Cattle

scholarly journals Detection of Bovine TMEM95 p.Cys161X Mutation in 13 Chinese Indigenous Cattle Breeds

Animals ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 444 ◽  
Author(s):  
Sihuan Zhang ◽  
Kun Peng ◽  
Guoliang Zhang ◽  
Yang Cao ◽  
Meng Zhang ◽  
...  
Keyword(s):  
Amino Acids ◽  
Genetic Marker ◽  
Molecular Breeding ◽  
Transmembrane Protein ◽  
Amplification Refractory Mutation System ◽  
Indigenous Cattle ◽  
Cattle Breeds ◽  
Indel Mutation ◽  
Chinese Cattle ◽  
Mutation System

Chinese indigenous cattle breeds have abundant genetic resources, which are valuable for the molecular breeding of cattle around the world. Thus, identifying important candidate genes and their genetic markers is very important for cattle molecular breeding. A previous study found that a nonsense mutation (rs378652941, c.483C > A, p.Cys161X) in the bovine transmembrane protein 95 gene (TMEM95) seriously reduced the reproductive performance in bulls, but few studies have detected this mutation in Chinese indigenous cattle breeds. Since the mutation c.483C > A may serve as a potential genetic marker for selecting higher fertility bulls, in the present study, using tetra-primer amplification refractory mutation system PCR (T-ARMS-PCR), forced PCR restriction fragment length polymorphism (forced PCR-RFLP), and DNA sequencing methods, the mutation c.483C > A was detected in 765 individuals from 13 Chinese cattle breeds. However, the results showed that this mutation did not exist at this locus in our analyzed breeds. Interestingly, we identified a newly frameshift insertion/deletion (indel) mutation (NC_037346.1: g.27056998_27057000delCT) in the bovine TMEM95 gene in 11 cattle breeds, which changed the location of the termination codon and changed the 16 amino acids in the C-terminal to 21 amino acids. Combined with previous studies, our study provides evidence that in Chinese cattle breeds the mutation c.483C > A cannot be used as a genetic marker in molecular breeding.

ZBTB38 gene polymorphism associated with body measurement traits in native Chinese cattle breeds

Gene ◽  
2013 ◽  
Vol 513 (2) ◽  
pp. 272-277 ◽  
Author(s):  
Yongfeng Liu ◽  
Linsen Zan ◽  
Yaping Xin ◽  
Wanqiang Tian ◽  
Linqiang Li ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Body Measurement ◽  
Cattle Breeds ◽  
Chinese Cattle ◽  
Body Measurement Traits

scholarly journals MTOR Variation Related to Heat Resistance of Chinese Cattle

Animals ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 915 ◽  
Author(s):  
Qingqing Ning ◽  
Kaixing Qu ◽  
Quratulain Hanif ◽  
Yutang Jia ◽  
Haijian Cheng ◽  
...  
Keyword(s):  
Heat Tolerance ◽  
Mean Annual Temperature ◽  
Opposite Pattern ◽  
Indigenous Cattle ◽  
Cattle Breeds ◽  
Chinese Cattle ◽  
Damage Repair ◽  
Temperature Heat ◽  
Humidity Index ◽  
Hot Environments

With the inexorable rise of global temperature, heat stress deserves more and more attention in livestock agriculture. Previous studies have shown that the mechanistic target of rapamycin (MTOR) (NC_037343.1:c.2062G>C) gene contributes to the repair of DNA damage repair and is associated with the adaptation of camels in dry and hot environments. However, it is unknown whether this mutation is related to the heat tolerance of Chinese cattle. In this study, PCR and sequencing were used to type the mutation locus in 1030 individuals of 37 cattle breeds. The analysis results showed that the frequency of G allele of the locus gradually diminished from the northern group to the southern group of native Chinese cattle, whereas the frequency of the C allele showed an opposite pattern, displaying a significant geographical difference across native Chinese cattle breeds. Additionally, an analysis of the locus in Chinese indigenous cattle revealed that this SNP was significantly associated with mean annual temperature (T), relative humidity (RH) and temperature humidity index (THI) (p < 0.01), suggesting that cattle with C allele was distributed in regions with higher T, RH and THI. In conclusion, this study proved that the mutation of MTOR gene in Chinese cattle could be associated with the heat tolerance.

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