scholarly journals Association between Polymorphisms of MSTN and MYF5 Genes and Growth Traits in Three Chinese Cattle Breeds

2007 ◽  
Vol 20 (12) ◽  
pp. 1798-1804 ◽  
Author(s):  
R. F. Zhang ◽  
H. Chen ◽  
C. Z. Lei ◽  
C. L. Zhang ◽  
X. Y. Lan ◽  
...  
2016 ◽  
Vol 59 (4) ◽  
pp. 469-476 ◽  
Author(s):  
Yunyun Jin ◽  
Hanfang Cai ◽  
Jiming Liu ◽  
Fengpeng Lin ◽  
Xinglei Qi ◽  
...  

Abstract. Paired box 7 (Pax7) gene, a member of the paired box gene family, plays a critical role in animal growth and muscle development, especially in cell proliferation and self-renewal. The aim of this study was to detect the 10 base pair (bp) duplication insertion/deletion (indel) in the promoter region within the bovine Pax7 gene as well as its association with growth traits. Herein, a total of 718 individuals from five Chinese cattle breeds were sampled and detected. The 10 bp duplication indel was found in these cattle breeds and there were three genotypes: II (insertion/insertion), ID (insertion/deletion), and DD (deletion/deletion). Moreover, this indel was significantly associated with the body weight in Xianan cattle (P = 0.006), the body height in Jinjiang cattle (P = 0.046), and the hip width in Pi'nan cattle (P = 0.020). Consistently, the individuals with II genotype showed better phenotypic traits than those with the other genotypes in these five breeds. These findings suggest that the 10 bp duplication indel within the bovine Pax7 gene could be considered as an effective DNA molecular marker that provides valuable theoretical basis for marker-assisted selection (MAS) in beef cattle in the future.


2009 ◽  
Vol 37 (1) ◽  
pp. 541-546 ◽  
Author(s):  
F. Li ◽  
H. Chen ◽  
C. Z. Lei ◽  
G. Ren ◽  
J. Wang ◽  
...  

2009 ◽  
Vol 37 (1) ◽  
pp. 501-505 ◽  
Author(s):  
F. Li ◽  
H. Chen ◽  
C. Z. Lei ◽  
G. Ren ◽  
J. Wang ◽  
...  

Gene ◽  
2019 ◽  
Vol 689 ◽  
pp. 166-171 ◽  
Author(s):  
Jia-Lin Zhong ◽  
Jia-Wei Xu ◽  
Jian Wang ◽  
Yi-fan Wen ◽  
Hui Niu ◽  
...  

Gene ◽  
2021 ◽  
pp. 146014
Author(s):  
Peng Yang ◽  
Cuicui Cai ◽  
Mengxiao Niu ◽  
Xian Liu ◽  
Hongli Wang ◽  
...  

Gene ◽  
2021 ◽  
Vol 769 ◽  
pp. 145201
Author(s):  
Shijie Lyu ◽  
Peng Yang ◽  
Yanyong Liu ◽  
Tian Song ◽  
Zijing Zhang ◽  
...  

2017 ◽  
Vol 62 (No. 4) ◽  
pp. 157-167
Author(s):  
N. Chen ◽  
F. Wang ◽  
N. Yu ◽  
Y. Gao ◽  
J. Huang ◽  
...  

The primary agent of mastitis is a wide spectrum of bacterial strains; however, viral-related mastitis has also been reported. The MX dynamin-like GTPase 1 (MX1) gene has been demonstrated to confer positive antiviral responses to many viruses, and may be a suitable candidate gene for the study of disease resistance in dairy cattle. The present study was conducted to investigate the genetic diversity of the MX1 gene in Chinese cattle breeds and its effects on mastitis in Holstein cows. First, polymorphisms were identified in the complete coding region of the bovine MX1 gene in 14 Chinese cattle breeds. An association study was then carried out, utilizing polymorphisms detected in Holstein cows to determine the associations of these single nucleotide polymorphisms (SNPs) with mastitis. We identified 13 previously reported SNPs in Chinese domestic cattle and four of them in Holstein cattle. A novel 12 bp indel was also discovered in Holstein cattle. In addition, haplotype frequencies and linkage disequilibrium of four SNPs detected in Holstein cows were investigated. Analysis of these four SNPs in Chinese Holstein cows revealed two SNPs (g.143181370 T&gt;C and g.143182088 C&gt;T)<br /> significantly (P &lt; 0.05) associated with somatic cell score (SCS). The results indicated that SNPs in the MX1 gene might contribute to the variations observed in the SCS of dairy cattle. Therefore, implementation of these two mutations in selection indexes of the dairy industry might be beneficial by favouring the selection individuals with lower SCS.


2017 ◽  
Vol 46 (1) ◽  
pp. 505-511 ◽  
Author(s):  
Qing Yang ◽  
Sihuan Zhang ◽  
Liangliang Liu ◽  
Chuzhao Lei ◽  
Xinglei Qi ◽  
...  

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