scholarly journals High frequency of microsatellite instability in sporadic colorectal cancer patients in Iran

2011 ◽  
Vol 10 (4) ◽  
pp. 3520-3529 ◽  
Author(s):  
M. Moghbeli ◽  
O. Moaven ◽  
E. Dadkhah ◽  
M. Farzadnia ◽  
N.M. Roshan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
High Frequency ◽  
Sporadic Colorectal Cancer ◽  
Colorectal Cancer Patients

scholarly journals Predictive model for high-frequency microsatellite instability in colorectal cancer patients over 50 years of age

2017 ◽  
Vol 6 (6) ◽  
pp. 1255-1263 ◽  
Author(s):  
Kenji Fujiyoshi ◽  
Tatsuro Yamaguchi ◽  
Miho Kakuta ◽  
Akemi Takahashi ◽  
Yoshiko Arai ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Predictive Model ◽  
Cancer Patients ◽  
High Frequency ◽  
Colorectal Cancer Patients

scholarly journals Reduced Plasma Levels of Very-Long-Chain Dicarboxylic Acid 28:4 in Italian and Brazilian Colorectal Cancer Patient Cohorts

Metabolites ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 91 ◽  
Author(s):  
Paul Wood ◽  
Michelle Donohue ◽  
John Cebak ◽  
Taylor Beckmann ◽  
Márcia Messias ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Dicarboxylic Acid ◽  
Cancer Patients ◽  
Plasma Levels ◽  
High Resolution Mass Spectrometry ◽  
Sporadic Colorectal Cancer ◽  
Inherited Susceptibility ◽  
Potential Biomarker ◽  
Colorectal Cancer Patients ◽  
Long Chain

Background: There are currently no blood-based biomarkers for early diagnosis of colorectal cancer. Previous research has suggested that very-long-chain dicarboxylic acid (VLCDCA) 28:4 might be such a biomarker. Methods: Using high-resolution mass spectrometry, we analyzed VLCDCA 28:4 in the plasma of colorectal cancer patients in Italian [n = 62] and Brazilian [n = 52] cohorts. Additionally, we investigated individuals diagnosed with familial adenomatous polyposis (FAP; n = 27), one of the most important clinical forms of inherited susceptibility to colorectal cancer. Results: Decrements in plasma levels of VLCDCA 28:4 were monitored in colorectal cancer patients. These decreases were independent of the stage of tumor development and the individual’s age. However, no decrements in VLCDCA 28:4 were monitored in FAP patients. Conclusions: The plasma levels of VLCDCA 28:4 represent a potential biomarker of sporadic colorectal cancer. In addition, it is possible that resupply of this anti-inflammatory lipid may represent a new therapeutic strategy for CRC and inflammatory disorders.

scholarly journals Advantage of HSP110 (T17) marker inclusion for microsatellite instability (MSI) detection in colorectal cancer patients

Oncotarget ◽  
2018 ◽  
Vol 9 (47) ◽  
pp. 28691-28701 ◽  
Author(s):  
Gustavo Noriz Berardinelli ◽  
Cristovam Scapulatempo-Neto ◽  
Ronílson Durães ◽  
Marco Antônio de Oliveira ◽  
Denise Guimarães ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
Colorectal Cancer Patients

scholarly journals Detection of c-Ki-ras mutations in faecal samples from sporadic colorectal cancer patients.

Gut ◽  
1995 ◽  
Vol 36 (1) ◽  
pp. 81-86 ◽  
Author(s):  
J Smith-Ravin ◽  
J England ◽  
I C Talbot ◽  
W Bodmer
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Sporadic Colorectal Cancer ◽  
Ras Mutations ◽  
Faecal Samples ◽  
Colorectal Cancer Patients

Impact of Preoperative Microsatellite Instability Testing on Surgical Management in Young-Onset Colorectal Cancer Patients: Results From a Reflex Testing Protocol

2011 ◽  
Vol 140 (5) ◽  
pp. S-1031-S-1032
Author(s):  
Jennifer Holder-Murray ◽  
Rajesh Pendlimari ◽  
Lisa Boardman ◽  
Thomas C. Smyrk ◽  
David W. Larson ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
Surgical Management ◽  
Young Onset ◽  
Testing Protocol ◽  
Reflex Testing ◽  
Colorectal Cancer Patients

Abstract B45: Microsatellite instability among disenfranchised minority colorectal cancer patients

2014 ◽  
Author(s):  
Daniel A. Sussman ◽  
Shivali Berera ◽  
Peter Hosein ◽  
Feng Miao ◽  
Tulay Koru-Sengul ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
Colorectal Cancer Patients

Microsatellite Instability of Colorectal Cancer and Adenoma in Synchronous Multiple Colorectal Cancer Patients with Associated Extracolonic Malignancies

Surgery Today ◽  
2001 ◽  
Vol 31 (5) ◽  
pp. 405-409
Author(s):  
Eiji Ueda ◽  
Toshiaki Watanabe ◽  
Hironori Ishigami ◽  
Naoyuki Umetani ◽  
Shin Sasaki ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
Colorectal Cancer Patients

A novel panel to detect microsatellite instability and concordance with clinical reference methods in colorectal cancer patients.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e22135-e22135
Author(s):  
Bart Claes ◽  
Rudi Rossau ◽  
Liesbeth Bernaerts ◽  
Els Fransen ◽  
Diether Lambrechts ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
Reference Methods ◽  
Colorectal Cancer Patients

scholarly journals Promoter methylation of ITF2, but not APC, is associated with microsatellite instability in two populations of colorectal cancer patients

BMC Cancer ◽  
2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Andrea J. Savio ◽  
Darshana Daftary ◽  
Elizabeth Dicks ◽  
Daniel D. Buchanan ◽  
Patrick S. Parfrey ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
Promoter Methylation ◽  
Colorectal Cancer Patients ◽  
Two Populations
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