scholarly journals Clinical Significance and Prognostic Relevance of Microsatellite Instability in Sporadic Colorectal Cancer Patients

2017 ◽  
Vol 18 (1) ◽  
pp. 107 ◽  
Author(s):  
Angelika Copija ◽  
Dariusz Waniczek ◽  
Andrzej Witkoś ◽  
Katarzyna Walkiewicz ◽  
Ewa Nowakowska-Zajdel
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
Clinical Significance ◽  
Sporadic Colorectal Cancer ◽  
Prognostic Relevance ◽  
Colorectal Cancer Patients

scholarly journals Prognostic Relevance of KRAS Mutation in Colorectal Cancer Patients Without Microsatellite Instability

2014 ◽  
Vol 25 ◽  
pp. ii68
Author(s):  
Khorshidi Fatemeh ◽  
Yaghoob Taleghani Mohammad ◽  
Irani Shemirani Atena ◽  
Pourhosseingholi Mohammad Amin ◽  
Nazemalhosseini Mojarad Ehsan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
Kras Mutation ◽  
Prognostic Relevance ◽  
Colorectal Cancer Patients

scholarly journals High frequency of microsatellite instability in sporadic colorectal cancer patients in Iran

2011 ◽  
Vol 10 (4) ◽  
pp. 3520-3529 ◽  
Author(s):  
M. Moghbeli ◽  
O. Moaven ◽  
E. Dadkhah ◽  
M. Farzadnia ◽  
N.M. Roshan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
High Frequency ◽  
Sporadic Colorectal Cancer ◽  
Colorectal Cancer Patients

scholarly journals Reduced Plasma Levels of Very-Long-Chain Dicarboxylic Acid 28:4 in Italian and Brazilian Colorectal Cancer Patient Cohorts

Metabolites ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 91 ◽  
Author(s):  
Paul Wood ◽  
Michelle Donohue ◽  
John Cebak ◽  
Taylor Beckmann ◽  
Márcia Messias ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Dicarboxylic Acid ◽  
Cancer Patients ◽  
Plasma Levels ◽  
High Resolution Mass Spectrometry ◽  
Sporadic Colorectal Cancer ◽  
Inherited Susceptibility ◽  
Potential Biomarker ◽  
Colorectal Cancer Patients ◽  
Long Chain

Background: There are currently no blood-based biomarkers for early diagnosis of colorectal cancer. Previous research has suggested that very-long-chain dicarboxylic acid (VLCDCA) 28:4 might be such a biomarker. Methods: Using high-resolution mass spectrometry, we analyzed VLCDCA 28:4 in the plasma of colorectal cancer patients in Italian [n = 62] and Brazilian [n = 52] cohorts. Additionally, we investigated individuals diagnosed with familial adenomatous polyposis (FAP; n = 27), one of the most important clinical forms of inherited susceptibility to colorectal cancer. Results: Decrements in plasma levels of VLCDCA 28:4 were monitored in colorectal cancer patients. These decreases were independent of the stage of tumor development and the individual’s age. However, no decrements in VLCDCA 28:4 were monitored in FAP patients. Conclusions: The plasma levels of VLCDCA 28:4 represent a potential biomarker of sporadic colorectal cancer. In addition, it is possible that resupply of this anti-inflammatory lipid may represent a new therapeutic strategy for CRC and inflammatory disorders.

scholarly journals Advantage of HSP110 (T17) marker inclusion for microsatellite instability (MSI) detection in colorectal cancer patients

Oncotarget ◽  
2018 ◽  
Vol 9 (47) ◽  
pp. 28691-28701 ◽  
Author(s):  
Gustavo Noriz Berardinelli ◽  
Cristovam Scapulatempo-Neto ◽  
Ronílson Durães ◽  
Marco Antônio de Oliveira ◽  
Denise Guimarães ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
Colorectal Cancer Patients

scholarly journals Detection of c-Ki-ras mutations in faecal samples from sporadic colorectal cancer patients.

Gut ◽  
1995 ◽  
Vol 36 (1) ◽  
pp. 81-86 ◽  
Author(s):  
J Smith-Ravin ◽  
J England ◽  
I C Talbot ◽  
W Bodmer
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Sporadic Colorectal Cancer ◽  
Ras Mutations ◽  
Faecal Samples ◽  
Colorectal Cancer Patients

Clinical significance of genetic alteration in plasma of colorectal cancer patients

2001 ◽  
Vol 37 ◽  
pp. S41
Author(s):  
T. Lecomte ◽  
A. Berger ◽  
F. Zinzindouhoue ◽  
S. Micard ◽  
B. Landi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Clinical Significance ◽  
Genetic Alteration ◽  
Colorectal Cancer Patients

Impact of Preoperative Microsatellite Instability Testing on Surgical Management in Young-Onset Colorectal Cancer Patients: Results From a Reflex Testing Protocol

2011 ◽  
Vol 140 (5) ◽  
pp. S-1031-S-1032
Author(s):  
Jennifer Holder-Murray ◽  
Rajesh Pendlimari ◽  
Lisa Boardman ◽  
Thomas C. Smyrk ◽  
David W. Larson ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Cancer Patients ◽  
Surgical Management ◽  
Young Onset ◽  
Testing Protocol ◽  
Reflex Testing ◽  
Colorectal Cancer Patients
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