scholarly journals Synthesis, Characterization and Antimicrobial Activities of Sulfadiazine Schiff Base and Phenyl Dithiocarbamate Mixed Ligand Metal Complexes

2018 ◽  
Vol 08 (08) ◽  
pp. 346-354
Author(s):  
Benjamin Chibuzo Ejelonu ◽  
Sulaiman Adeoye Olagboye ◽  
Oluwatoba Emmanuel Oyeneyin ◽  
Oladipo Adebayo Ebiesuwa ◽  
Oluwatomisin Emmanuel Bada
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Antimicrobial Activities ◽  
Mixed Ligand

scholarly journals Mixed Ligand Complexes of Copper(II) and Cobalt(II) with Hydrazones Derivatives and ortho-Vanillin: Syntheses, Characterizations and Antimicrobial Activity

2019 ◽  
Vol 35 (6) ◽  
pp. 1722-1730
Author(s):  
Israa A. Alghamdi ◽  
Mohamed Abdelbaset ◽  
Ines El Mannoubi
Keyword(s):  
Metal Complexes ◽  
Antimicrobial Activities ◽  
Molar Conductance ◽  
Mixed Ligand ◽  
Planar Geometry ◽  
Central Metal ◽  
Bacterial Strains ◽  
Hydrazone Ligand ◽  
Metal Atoms ◽  
Square Planar

The purpose of this paper was to synthesis new mixed-ligand Cu(II) and Co(II) metal complexes utilizing bidentate and tridentate donor hydrazones derivatives as primary ligands and o-vanillin as co-ligand. The obtained compounds were characterized by elemental analysis, Infrared, UV-Vis., 1H-NMR, Mass spectra, molar conductance, thermal analysis and atomic absorption spectroscopy (ASS). Spectroscopic analysis results indicated that the hydrazone ligand (L1) behave as tridentate (ONO) and forms metal complexes having distorted square planar geometry. While the ligands (L2, L3 AND L4) behave as bidentate (NO) and forms metal complexes having octahedral geometry around the central metal atoms. The antimicrobial potentials were assessed for the ligand (L2) and its metal complexes only and were screened against six types of bacterial strains and one fungal strain. The antimicrobial activities results of the tested compounds showed enhanced activity of the complexes over their parent ligands.

scholarly journals Synthesis, characterisation and antimicrobial activities of mixed ligand complexes of Mn (II), Fe (II) and Co(II) containing N,N'-bis (o-anisaldehyde) p-phenylenediamine (tetradentate schiff base) and gylcine

2018 ◽  
Vol 11 (1) ◽  
pp. 32-36
Author(s):  
I.T. Siraj ◽  
M Sule
Keyword(s):  
Antimicrobial Activity ◽  
Schiff Base ◽  
Mixed Ligand Complex ◽  
Antimicrobial Activities ◽  
Molar Conductance ◽  
Bidentate Ligand ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes ◽  
Ligand Complex ◽  
Tetradentate Schiff Base

Complexes of Mn(II), Fe(II) and Co(II) containing N, N’-bis[o-anisaldehyde]p-phenylenediamine tetradentate Schiff base as primary ligand and glycine as secondary bidentate ligand have been synthesized by reflux in 1:1:1 mole ratio and characterized both analytically and spectroscopically. Molar conductance measurement (69.02 to 86.30Ω–1 cm2 mol–1) of the complexes indicated they are weak electrolyte and magnetic susceptibility measurement shows values in range of 4.53 to 5.59BM indicating their paramagnetism. The infrared data suggested that the Schiff base coordinated via the two nitrogen atoms of the azomethine groups (1628 to 1680 cm-1) and the oxygen atoms of the adjacent methoxy groups (1341 to 1389 cm-1), while glycine coordinated via the nitrogen atom of the amino group (3060-3324 cm-1) and the oxygen atom of the carboxylate anion. Based on the analytical and spectroscopic data the complexes may be assigned an octahedral geometries and molecular formulae of the form [M(L)Gly], where M = Mn, Fe and Co, L=Schiff base and Gly = glycine. The Schiff base and its mixed ligand complexes were screened for antimicrobial activity against Staphylococcus aureus, Escherichia coli, Salmonella typhi, Mucor inducus and Aspergillus fumigatus. The complexes exhibited enhanced antimicrobial activity (10mm to 18mm) at 60 µg/disc as compared to 10mm activity of the uncoordinated Schiff base at the same concentration.Keywords: Mixed ligand complex; Schiff base, Glycine, p-phenylenediamine, o-anisaldehyde

scholarly journals Synthesis of some Novel Mixed Ligand Complexes of Ni(II) and their Characterization

2021 ◽  
Vol 37 (5) ◽  
pp. 1152-1157
Author(s):  
Mohd Saleem ◽  
Mohd Riaz
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Magnetic Moment ◽  
Conductivity Measurement ◽  
Nickel Chloride ◽  
Mixed Ligand ◽  
Aminosalicylic Acid ◽  
Metal Analysis ◽  
Schiff Base Ligands ◽  
Ir Analysis

A new series of metal Complexes were prepared by refluxing nickel chloride with hot methanolic solution mixture of 8-Hydroxyquinoline and Schiff bases(L1-L6). Schiff base ligands were synthesised by the condensation of 4-aminopheno, 4-aminosalicylic acid, 2-aminobenzthiazole with salicylaldehyde and vanillin. The metal complexes have been characterised by gravimetric metal analysis, magnetic moment,conductivity measurement, 1HNMR and IR analysis.

scholarly journals Antitumor and Antimicrobial Potential of Manganese(II), Nickel(II) and Copper(II) Complexes of 4-Methoxy Benzohydrazide Derived Schiff Base Ligand

2021 ◽  
Vol 11 (1) ◽  
pp. 3249-3260
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Schiff Base Ligand ◽  
Antimicrobial Activities ◽  
Molar Ratio ◽  
Gram Positive Bacteria ◽  
Ft Ir ◽  
Dose Dependent

Herein, we describe the synthesis and characterization of a Schiff base ligand (E)-N'-(2-hydroxybenzylidene)-4-methoxybenzohydrazide (HBMB) and its Mn(II), Ni(II), and Cu(II) metal complexes (C1-C3) respectively. The ligand HBMB was synthesized by reacting condensation of salicylaldehyde and 4-methoxy benzohydrazide in a 1:1 molar ratio. The structure of HBMB and its metal complexes (C1-C3) were evaluated by using UV-Vis, FT-IR, 1H-NMR, mass spectroscopy as well as on the basis of elemental analysis, conductivity measurements, and thermogravimetric techniques (TGA). The synthesized molecules' tumoricidal properties were performed against human breast cancer (MCF-7) and colon cancer (HT 29) cell lines. The biological results indicated that the ligand, HBMB, and metal complexes possess dose-dependent selective cytotoxicity against the tested carcinoma cells. The synthesized compounds were further evaluated for their in vitro antimicrobial activities against Gram-positive bacteria (Staphylococcus aureus), Gram-negative bacteria (Escherichia coli), and fungal strains (Aspergillus niger).

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