scholarly journals Prevalence of Latent Tuberculosis (LTB) among Household Contacts of Newly Diagnosed Omani Pulmonary Tuberculosis Patients

2020 ◽  
Vol 08 (01) ◽  
pp. 11-21
Author(s):  
Jeffrey Singh ◽  
Lamiya Balushi ◽  
Nada Mahrazi ◽  
Esklid Peterson ◽  
Olivier Koole ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Latent Tuberculosis ◽  
Newly Diagnosed ◽  
Tuberculosis Patients ◽  
Household Contacts

scholarly journals History of household member with tuberculosis or related death in newly diagnosed patients in India

2020 ◽  
Vol 10 (2) ◽  
pp. 53-56
Author(s):  
H. D. Shewade ◽  
V. Gupta ◽  
S. Satyanarayana ◽  
S. S. Chadha ◽  
S. Pandurangan ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Preventive Treatment ◽  
Population Level ◽  
Household Member ◽  
Newly Diagnosed ◽  
Household Contacts ◽  
Household Transmission ◽  
Smear Positive Pulmonary Tuberculosis ◽  
History Of ◽  
Potential Population

Among new smear-positive pulmonary tuberculosis (TB) patients aged 15 years from marginalised populations in India, one in four had a history of a household member with TB and one in 10 had a TB-related death in the household. This contribution of household transmission to overall TB transmission provides evidence for a potential population-level benefit of TB preventive treatment for all household contacts (without active TB). Females with TB had a significantly higher household TB exposure than males. Targeted TB preventive treatment (if implemented in a phased manner) among female household contacts may be explored after considering other factors.

scholarly journals Latent tuberculosis among household contacts of pulmonary tuberculosis cases in Nairobi, Kenya

2020 ◽  
Vol 37 ◽  
Author(s):  
Susan Odera ◽  
Marianne Mureithi ◽  
Andrew Aballa ◽  
Noel Onyango ◽  
Omu Anzala ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Latent Tuberculosis ◽  
Household Contacts

scholarly journals Oxidative stress biomarkers in pulmonary tuberculosis patients in Gombe, North-eastern Nigeria

2019 ◽  
Vol 10 (6) ◽  
pp. 57-62 ◽  
Author(s):  
Mohammed Haruna Yeldu ◽  
Yakubu Ibrahim ◽  
Shehu Abubakar Akuyam ◽  
Isah Muhammad Danasabe ◽  
Buhari Shehu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Pulmonary Tuberculosis ◽  
Total Antioxidant Status ◽  
Serum Levels ◽  
Newly Diagnosed ◽  
Oxidative Stress Biomarkers ◽  
Tuberculosis Patients ◽  
Stress Biomarkers ◽  
North Eastern ◽  
Total Antioxidant

Background: Oxidative stress may play an important role in the pathogenesis of pulmonary tuberculosis (PTB). To our knowledge there is paucity of data on the status of oxidative stress biomarkers among PTB patients in Gombe, North-eastern Nigeria. Our study was designed to evaluate the oxidative stress biomarkers in pulmonary tuberculosis patients in Gombe, North-eastern Nigeria. Aims and Objectives: To determine the serum levels of oxidative stress biomarkers among patients with pulmonary tuberculosis in Gombe metropolis, North-eastern Nigeria and to assess the correlation between the oxidative stress biomarkers in pulmonary tuberculosis patients. Materials and Methods: A cross sectional comparative study was conducted in a tertiary health care facility with 40 pulmonary tuberculosis (PTB) patients on anti-TB drugs treatment (ATT), 40 newly diagnosed PTB patients not yet on anti-TB drugs treatment (ATT-naïve) and 40 age- and sex-marched apparently healthy subjects (controls). Serum total antioxidant status (TAS), total oxidant status (TOS), malondialdehyde (MDA), nitric oxide (NO) and oxidative stress index (OSI) determined using standard techniques. Data was analysed using INSTAT® (Graph Pad Software Inc., La Jolla, CA, USA). Results: Serum levels of TOS, OSI, MDA and NO were significantly (p ˂ 0.001) increased in PTB patients (ATT and ATT-naïve) when compared with healthy individuals. Serum TAS and body mass index (BMI) were significantly (p ˂ 0.001) decreased in PTB patients when compared with healthy individuals. Serum TOS significantly correlated with serum OSI, MDA and NO in ATT-naïve PTB patients. Conclusion: This study observed an increased oxidative stress biomarkers and decreased total antioxidant status in newly diagnosed pulmonary tuberculosis patients and those on treatment. Our findings suggest that antioxidants supplementation and improved nutrition in the management of pulmonary tuberculosis patients may go a long way in preventing the oxidative onslaught and further complications in PTB patients.

IL-6 and IL-18 cytokine gene variants of pulmonary tuberculosis patients with co-morbid diabetes mellitus and their household contacts in Hyderabad

Gene ◽  
2017 ◽  
Vol 627 ◽  
pp. 298-306 ◽  
Author(s):  
Meenakshi Ponnana ◽  
Ramya Sivangala ◽  
Lavanya Joshi ◽  
Vijayalakshmi Valluri ◽  
Sumanlatha Gaddam
Keyword(s):  
Diabetes Mellitus ◽  
Pulmonary Tuberculosis ◽  
Gene Variants ◽  
Cytokine Gene ◽  
Tuberculosis Patients ◽  
Household Contacts

Eight Months vs Six Months Anti-TB Regimen in the Treatment of Newly Diagnosed Pulmonary Tuberculosis Patients in Nigeria

2015 ◽  
Vol 8 (10) ◽  
pp. 836-841 ◽  
Author(s):  
Olusoji Daniel ◽  
Olusola Adejumo ◽  
Hussein Abdulrrazzaq ◽  
Mustapha Gidado ◽  
Olajumoke Onazi ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Newly Diagnosed ◽  
Tuberculosis Patients
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