类钙调神经磷酸酶B亚基蛋白CBL和它们的作用激酶蛋白CIPKCalcineurin B-Like Proteins and Their Interacting Protein Kinases

2012 ◽  
Vol 01 (02) ◽  
pp. 9-12
Author(s):  
沈 清
Keyword(s):  
Protein Kinases ◽  
Interacting Protein ◽  
Calcineurin B

scholarly journals Roles of calcineurin B-like protein-interacting protein kinases in innate immunity in rice

2010 ◽  
Vol 5 (8) ◽  
pp. 1045-1047 ◽  
Author(s):  
Takamitsu Kurusu ◽  
Jumpei Hamada ◽  
Haruyasu Hamada ◽  
Shigeru Hanamata ◽  
Kazuyuki Kuchitsu
Keyword(s):  
Innate Immunity ◽  
Protein Kinases ◽  
Interacting Protein ◽  
Calcineurin B

Isolation and Expression Analysis of a Putative CIPK Gene in Halophyte Sesuvium portulacastrumand L.

2014 ◽  
Vol 997 ◽  
pp. 215-220
Author(s):  
Yan Ping Hu ◽  
Yang Zhou ◽  
Cheng Long Yang ◽  
Jiao Liu ◽  
Rui Jun Duan ◽  
...  
Keyword(s):  
Amino Acids ◽  
Molecular Weight ◽  
Phylogenetic Analysis ◽  
Protein Kinases ◽  
Expression Analysis ◽  
Significant Role ◽  
Intracellular Signaling ◽  
Transmembrane Domain ◽  
Interacting Protein ◽  
Calcineurin B

Calcium plays a significant role in intracellular signaling. Calcineurin B-like proteins (CBLs) and their target proteins, CBL-interacting protein kinases (CIPKs) have emerged a calcium network responsing to stresses in plants. In this study, we cloned a CIPK gene,SpCIPK8, from the halophyte plantSesuvium portulacastrumandL. Bioinformation analysis showed that the cDNA ofSpCIPK8was 1344 bp and encoded 447 amino acids with a molecular weight of 50.72 KD and an isoelectric point of 7.19. One transmembrane domain exists in this hydrophilic protein. Phylogenetic analysis showed that SpCIPK8 was similar with AtCIPK8 inArabidopsis.The expression level ofSpCIPK8in stems was three times higher than that in roots and the level in leaves was two times higher than that in roots.

scholarly journals Genome-Wide Identification of CBL-CIPK Gene Family in Honeysuckle (Lonicera japonica Thunb.) and Their Regulated Expression Under Salt Stress

2021 ◽  
Vol 12 ◽  
Author(s):  
Luyao Huang ◽  
Zhuangzhuang Li ◽  
Qingxia Fu ◽  
Conglian Liang ◽  
Zhenhua Liu ◽  
...  
Keyword(s):  
Salt Stress ◽  
Protein Kinases ◽  
Stress Responses ◽  
Structure Prediction ◽  
Functional Divergence ◽  
Gene Families ◽  
Plant Responses ◽  
Interacting Protein ◽  
Protein Motifs ◽  
Insight Into

In plants, calcineurin B-like proteins (CBLs) are a unique group of Ca2+ sensors that decode Ca2+ signals by activating a family of plant-specific protein kinases known as CBL-interacting protein kinases (CIPKs). CBL-CIPK gene families and their interacting complexes are involved in regulating plant responses to various environmental stimuli. To gain insight into the functional divergence of CBL-CIPK genes in honeysuckle, a total of six LjCBL and 17 LjCIPK genes were identified. The phylogenetic analysis along with the gene structure analysis divided both CBL and CBL-interacting protein kinase genes into four subgroups and validated by the distribution of conserved protein motifs. The 3-D structure prediction of proteins shown that most LjCBLs shared the same Protein Data Bank hit 1uhnA and most LjCIPKs shared the 6c9Da. Analysis of cis-acting elements and gene ontology implied that both LjCBL and LjCIPK genes could be involved in hormone signal responsiveness and stress adaptation. Protein-protein interaction prediction suggested that LjCBL4 is hypothesized to interact with LjCIPK7/9/15/16 and SOS1/NHX1. Gene expression analysis in response to salinity stress revealed that LjCBL2/4, LjCIPK1/15/17 under all treatments gradually increased over time until peak expression at 72 h. These results demonstrated the conservation of salt overly sensitive pathway genes in honeysuckle and a model of Ca2+-LjCBL4/LjSOS3-LjCIPK16/LjSOS2 module-mediated salt stress signaling in honeysuckle is proposed. This study provides insight into the characteristics of the CBL-CIPK gene families involved in honeysuckle salt stress responses, which could serve as a foundation for gene transformation technology, to obtain highly salt-tolerant medicinal plants in the context of the global reduction of cultivated land.

scholarly journals The CBL–CIPK Pathway in Plant Response to Stress Signals

2020 ◽  
Vol 21 (16) ◽  
pp. 5668
Author(s):  
Xiao Ma ◽  
Quan-Hui Li ◽  
Ya-Nan Yu ◽  
Yi-Ming Qiao ◽  
Saeed ul Haq ◽  
...  
Keyword(s):  
Functional Characterization ◽  
Future Research ◽  
Complex Environments ◽  
Yield Improvement ◽  
Interacting Protein ◽  
Secondary Messenger ◽  
Calcineurin B ◽  
Response To Stress ◽  
Stress Signals

Plants need to cope with multitudes of stimuli throughout their lifecycles in their complex environments. Calcium acts as a ubiquitous secondary messenger in response to numerous stresses and developmental processes in plants. The major Ca2+ sensors, calcineurin B-like proteins (CBLs), interact with CBL-interacting protein kinases (CIPKs) to form a CBL–CIPK signaling network, which functions as a key component in the regulation of multiple stimuli or signals in plants. In this review, we describe the conserved structure of CBLs and CIPKs, characterize the features of classification and localization, draw conclusions about the currently known mechanisms, with a focus on novel findings in response to multiple stresses, and summarize the physiological functions of the CBL–CIPK network. Moreover, based on the gradually clarified mechanisms of the CBL–CIPK complex, we discuss the present limitations and potential prospects for future research. These aspects may provide a deeper understanding and functional characterization of the CBL–CIPK pathway and other signaling pathways under different stresses, which could promote crop yield improvement via biotechnological intervention.

scholarly journals Homeodomain-interacting Protein Kinases, a Novel Family of Co-repressors for Homeodomain Transcription Factors

1998 ◽  
Vol 273 (40) ◽  
pp. 25875-25879 ◽  
Author(s):  
Young Ho Kim ◽  
Cheol Yong Choi ◽  
Seung-Jae Lee ◽  
Mary Anne Conti ◽  
Yongsok Kim
Keyword(s):  
Transcription Factors ◽  
Protein Kinases ◽  
Interacting Protein ◽  
Homeodomain Transcription Factors
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