scholarly journals Evaluation of a Bubble CPAP System for Low Resource Settings

2021 ◽  
pp. respcare.08948
Author(s):  
Michelle Dundek ◽  
Ellie Ng ◽  
Brazil Abigail ◽  
M DiBlasi Robert ◽  
A Poli Jonathan ◽  
...  
Author(s):  
Michelle Dundek ◽  
Kamyar Mollazadeh-Moghaddam ◽  
Anuj Bellare ◽  
Thomas Burke ◽  
Rupam Sharma ◽  
...  

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0242590
Author(s):  
Megan Heenan ◽  
Jose D. Rojas ◽  
Z. Maria Oden ◽  
Rebecca Richards-Kortum

Respiratory distress due to preterm birth is a significant cause of death in low-resource settings. The introduction of continuous positive airway pressure (CPAP) systems to treat respiratory distress significantly reduced mortality in high-resource settings, but CPAP was only recently introduced in low-resource settings due to cost and infrastructure limitations. We evaluated pressure stability and imposed work of breathing (iWOB) of five CPAP systems used in low resource settings: the Fisher and Paykel bubble CPAP, the Diamedica baby CPAP, the Medijet nCPAP generator, and the first (2015) and second (2017) generation commercially available Pumani CPAPs. Pressure changes due to fresh gas flow were evaluated for each system by examining the relationship between flow and pressure at the patient interface for four pressures generated at the bottle (0, 3, 5, and 7 cm H2O); for the Medijet nCPAP generator, no bottle was used. The slope of the resulting relationship was used to calculate system resistance. Poiseuille’s law of resistance was used to investigate significant contributors to resistance. Resistance ranged from 0.05 to 1.40 cmH2OL/min; three CPAP devices had resistances < 0.4 cmH2OL/min: the Fisher and Paykel system, the Diamedica system, and the second generation Pumani bubble CPAP. The other two systems, the Medijet nCPAP generator and the first generation Pumani bCPAP, had resistances >1.0 cmH2OL/min. Imposed WOB was measured using an ASL5000 test lung to simulate the breath cycle for an infant (5.5 kg), a term neonate (4.0 kg), and a preterm neonate (2.5 kg). Imposed WOB ranged from 1.4 to 39.5 mJ/breath across all systems and simulated infant sizes. Changes in pressure generated by fresh gas flow, resistance, and iWOB differ between the five systems evaluated under ideal laboratory conditions. The available literature does not indicate that these differences affect clinical outcomes.


2021 ◽  
Vol 22 (Supplement 1 3S) ◽  
pp. 162-162
Author(s):  
R. Carroll ◽  
A. Smith ◽  
M. Chisti ◽  
P. Wilson ◽  
M. Eckerle ◽  
...  

2016 ◽  
Vol 03 (02) ◽  
pp. 079-083
Author(s):  
Lawrence Mbuagbaw ◽  
Francisca Monebenimp ◽  
Bolaji Obadeyi ◽  
Grace Bissohong ◽  
Marie-Thérèse Obama ◽  
...  

2020 ◽  
Author(s):  
Afework Kassu ◽  
Getnet Yimer ◽  
Solomon Benor ◽  
Kassahun Tesfaye ◽  
Yifokre Tefera ◽  
...  

2009 ◽  
Vol 2 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Allison Bingham ◽  
Amynah Janmohamed ◽  
Rosario Bartolini ◽  
Hilary M. Creed-Kanashiro ◽  
Yanuar Ruhweza Katahoire ◽  
...  

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