scholarly journals Pulmonary-Specific Intermountain Risk Score Predicts All-Cause Mortality via Spirometry, the Red Cell Distribution Width, and Other Laboratory Parameters

2015 ◽  
Vol 60 (9) ◽  
pp. 1314-1323 ◽  
Author(s):  
B. D. Horne ◽  
M. Hegewald ◽  
J. B. Muhlestein ◽  
H. T. May ◽  
E. J. Huggins ◽  
...  
2011 ◽  
Vol 39 (8) ◽  
pp. 1913-1921 ◽  
Author(s):  
Heidi S. Bazick ◽  
Domingo Chang ◽  
Karthik Mahadevappa ◽  
Fiona K. Gibbons ◽  
Kenneth B. Christopher

Haematologica ◽  
2015 ◽  
Vol 100 (10) ◽  
pp. e387-e389 ◽  
Author(s):  
T. S. Ellingsen ◽  
J. Lappegard ◽  
T. Skjelbakken ◽  
S. K. Braekkan ◽  
J.-B. Hansen

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Sadeer G. Al-Kindi ◽  
Marwan Refaat ◽  
Amin Jayyousi ◽  
Nidal Asaad ◽  
Jassim Al Suwaidi ◽  
...  

Background and Methods. Red cell distribution width (RDW) has emerged as a prognostic marker in patients with cardiovascular diseases. We investigated mortality in patients with diabetes included in the National Health and Nutrition Examination Survey, in relation to baseline RDW. RDW was divided into 4 quartiles (Q1: ≤12.4%, Q2: 12.5%–12.9%, Q3: 13.0%–13.7%, and Q4: >13.7%). Results. A total of 3,061 patients were included: mean age 61±14 years, 50% male, 39% White. Mean RDW was 13.2%±1.4%. Compared with first quartile (Q1) of RDW, patients in Q4 were more likely to be older, female, and African-American, have had history of stroke, myocardial infarction, and heart failure, and have chronic kidney disease. After a median follow-up of 6 years, 628 patient died (29% of cardiovascular disease). Compared with Q1, patients in Q4 were at increased risk for all-cause mortality (HR 3.44 [2.74–4.32], P<.001) and cardiovascular mortality (HR 3.34 [2.16–5.17], P<.001). After adjusting for 17 covariates, RDW in Q4 remained significantly associated with all-cause mortality (HR 2.39 [1.30–4.38], P=0.005) and cardiovascular mortality (HR 1.99 [1.17–3.37], P=0.011). Conclusion. RDW is a powerful and an independent marker for prediction of all-cause mortality and cardiovascular mortality in patients with diabetes.


Hypertension ◽  
2015 ◽  
Vol 66 (suppl_1) ◽  
Author(s):  
Suraj Raheja ◽  
Kush Patel ◽  
Ruchir Patel ◽  
Sagger Mawri ◽  
Alexander Michaels ◽  
...  

Background: Red cell distribution width (RDW) is a measure of the variability in size of erythrocytes. A high RDW value indicates greater variation in size between individual erythrocytes and has been shown to be an independent predictor of mortality in patients with coronary artery disease, heart failure and in patients undergoing percutaneous coronary intervention (PCI). The aim of this study was to evaluate the prognostic value of RDW in predicting clinical outcomes in patients with hypertensive crisis. Methods: We performed a retrospective study of 465 consecutive patients from January 2007 to March 2010 who presented with hypertensive crisis. Hypertensive crisis was defined as systolic BP >180 and/or diastolic BP >110mmHg with impending or progressive end organ dysfunction requiring inpatient hospitalization. The study sample consisted of 465 patients (38.9% men (181 of 465); mean age 59.6 ± 15.9). Baseline levels of RDW were measured at time of admission and analyzed as continuous and categorical variables (elevated RDW was defined as >14.5%). Multivariable regression analysis was performed for development of all-cause mortality, myocardial infarction, new-onset heart failure (defined as first time hospital admission for heart failure), stroke and MACE (MI, new-onset heart failure and stroke) at 2 years. Results: RDW > 14.5% was a strong independent predictor of all-cause mortality at 2 years (OR: 1.90, 95% CI: 1.1-3.3, p <0.05). Elevated RDW was also found to be an independent predictor of new-onset heart failure at 2 years (OR: 1.97, 95% CI: 1.1-3.7, p <0.05). Elevated RDW was not a predictor of MI, PCI or stroke at 2 years. Conclusions: Elevated RDW level in patients with hypertensive crisis was an independent predictor of all-cause mortality and new-onset heart failure in patients with hypertensive crisis.


2015 ◽  
Vol 113 (01) ◽  
pp. 193-200 ◽  
Author(s):  
Jostein Lappegård ◽  
Tove Skjelbakken ◽  
Sigrid Brækkan ◽  
John-Bjarne Hansen ◽  
Trygve S. Ellingsen

SummaryRecent studies suggest an association between red cell distribution width (RDW) and incident venous thromboembolism (VTE). We aimed to investigate the impact of RDW on risk of incident and recurrent VTE, and case-fatality, in a general population. RDW was measured in 26,223 participants enrolled in the Tromsø Study in 1994–1995. Incident and recurrent VTE events and deaths during follow-up were registered until January 1, 2012. Multivariate Cox proportional hazards regression models were used to calculate hazard ratios (HR) with 95% confidence intervals (CI). There were 647 incident VTE events during a median of 16.8 years of follow-up. Individuals with RDW in the highest quartile (RDW≥13.3%) had 50% higher risk of an incident VTE than those in the lowest quartile (RDW≤12.3%). The association was strongest for unprovoked deep-vein thrombosis (HR highest vs lowest quartile of RDW: 1.8, 95% CI 1.1–3.1). VTE patients with baseline RDW≥13.3% had 30% higher risk of all-cause mortality after the initial VTE event than VTE patients with RDW<13.3%. There were no association between RDW and risk of recurrent VTE. Our findings suggest that high RDW is a risk factor of incident VTE, and that RDW is a predictor of all-cause mortality in VTE patients.


Cardiology ◽  
2014 ◽  
Vol 130 (1) ◽  
pp. 23-24
Author(s):  
Sevket Balta ◽  
Mustafa Aparci ◽  
Cengiz Ozturk ◽  
Sait Demirkol ◽  
Turgay Celik

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