scholarly journals Red Cell Distribution Width Is Associated with All-Cause and Cardiovascular Mortality in Patients with Diabetes

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Sadeer G. Al-Kindi ◽  
Marwan Refaat ◽  
Amin Jayyousi ◽  
Nidal Asaad ◽  
Jassim Al Suwaidi ◽  
...  
Keyword(s):  
Cardiovascular Mortality ◽  
Red Cell Distribution Width ◽  
Red Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
Health And Nutrition ◽  
Increased Risk ◽  
All Cause Mortality ◽  
Patients With Diabetes ◽  
History Of

Background and Methods. Red cell distribution width (RDW) has emerged as a prognostic marker in patients with cardiovascular diseases. We investigated mortality in patients with diabetes included in the National Health and Nutrition Examination Survey, in relation to baseline RDW. RDW was divided into 4 quartiles (Q1: ≤12.4%, Q2: 12.5%–12.9%, Q3: 13.0%–13.7%, and Q4: >13.7%). Results. A total of 3,061 patients were included: mean age 61±14 years, 50% male, 39% White. Mean RDW was 13.2%±1.4%. Compared with first quartile (Q1) of RDW, patients in Q4 were more likely to be older, female, and African-American, have had history of stroke, myocardial infarction, and heart failure, and have chronic kidney disease. After a median follow-up of 6 years, 628 patient died (29% of cardiovascular disease). Compared with Q1, patients in Q4 were at increased risk for all-cause mortality (HR 3.44 [2.74–4.32], P<.001) and cardiovascular mortality (HR 3.34 [2.16–5.17], P<.001). After adjusting for 17 covariates, RDW in Q4 remained significantly associated with all-cause mortality (HR 2.39 [1.30–4.38], P=0.005) and cardiovascular mortality (HR 1.99 [1.17–3.37], P=0.011). Conclusion. RDW is a powerful and an independent marker for prediction of all-cause mortality and cardiovascular mortality in patients with diabetes.

scholarly journals Red cell distribution width and all-cause mortality in critically ill patients*

2011 ◽  
Vol 39 (8) ◽  
pp. 1913-1921 ◽  
Author(s):  
Heidi S. Bazick ◽  
Domingo Chang ◽  
Karthik Mahadevappa ◽  
Fiona K. Gibbons ◽  
Kenneth B. Christopher
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Red Cell Distribution Width ◽  
Red Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
All Cause Mortality

scholarly journals Impact of red cell distribution width on future risk of cancer and all-cause mortality among cancer patients - the Tromso Study

Haematologica ◽  
2015 ◽  
Vol 100 (10) ◽  
pp. e387-e389 ◽  
Author(s):  
T. S. Ellingsen ◽  
J. Lappegard ◽  
T. Skjelbakken ◽  
S. K. Braekkan ◽  
J.-B. Hansen
Keyword(s):  
Cancer Patients ◽  
Red Cell Distribution Width ◽  
Red Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
All Cause Mortality ◽  
Future Risk ◽  
Risk Of Cancer

Abstract 090: Outcomes of Hypertensive Crises as Predicted by Red Cell Distribution Width

Hypertension ◽  
2015 ◽  
Vol 66 (suppl_1) ◽  
Author(s):  
Suraj Raheja ◽  
Kush Patel ◽  
Ruchir Patel ◽  
Sagger Mawri ◽  
Alexander Michaels ◽  
...  
Keyword(s):  
Heart Failure ◽  
Independent Predictor ◽  
Hypertensive Crisis ◽  
Red Cell Distribution Width ◽  
Categorical Variables ◽  
Red Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
All Cause Mortality ◽  
New Onset

Background: Red cell distribution width (RDW) is a measure of the variability in size of erythrocytes. A high RDW value indicates greater variation in size between individual erythrocytes and has been shown to be an independent predictor of mortality in patients with coronary artery disease, heart failure and in patients undergoing percutaneous coronary intervention (PCI). The aim of this study was to evaluate the prognostic value of RDW in predicting clinical outcomes in patients with hypertensive crisis. Methods: We performed a retrospective study of 465 consecutive patients from January 2007 to March 2010 who presented with hypertensive crisis. Hypertensive crisis was defined as systolic BP >180 and/or diastolic BP >110mmHg with impending or progressive end organ dysfunction requiring inpatient hospitalization. The study sample consisted of 465 patients (38.9% men (181 of 465); mean age 59.6 ± 15.9). Baseline levels of RDW were measured at time of admission and analyzed as continuous and categorical variables (elevated RDW was defined as >14.5%). Multivariable regression analysis was performed for development of all-cause mortality, myocardial infarction, new-onset heart failure (defined as first time hospital admission for heart failure), stroke and MACE (MI, new-onset heart failure and stroke) at 2 years. Results: RDW > 14.5% was a strong independent predictor of all-cause mortality at 2 years (OR: 1.90, 95% CI: 1.1-3.3, p <0.05). Elevated RDW was also found to be an independent predictor of new-onset heart failure at 2 years (OR: 1.97, 95% CI: 1.1-3.7, p <0.05). Elevated RDW was not a predictor of MI, PCI or stroke at 2 years. Conclusions: Elevated RDW level in patients with hypertensive crisis was an independent predictor of all-cause mortality and new-onset heart failure in patients with hypertensive crisis.

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