scholarly journals Effect of the Anatomic Reservoir on Low-Flow Oxygen Delivery Via Nasal Cannula: Constant Flow Versus Pulse Flow With Portable Oxygen Concentrator

2014 ◽  
Vol 59 (8) ◽  
pp. 1199-1209 ◽  
Author(s):  
S. Zhou ◽  
R. L. Chatburn
Keyword(s):  
Oxygen Delivery ◽  
Nasal Cannula ◽  
Low Flow ◽  
Constant Flow ◽  
Pulse Flow ◽  
Oxygen Concentrator ◽  
Portable Oxygen

scholarly journals Randomised controlled trial to assess the effectiveness of apnoeic oxygenation in adults using low-flow or high-flow nasal cannula with head side elevation versus usual care to prevent desaturation during endotracheal intubation in the emergency department (ApOxED): study protocol

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e037964
Author(s):  
Shahan Waheed ◽  
Nazir Najeeb Kapadia ◽  
Muhammad Faisal Khan ◽  
Salima Mansoor Kerai ◽  
Ahmed Raheem ◽  
...  
Keyword(s):  
Endotracheal Intubation ◽  
Direct Laryngoscopy ◽  
Oxygen Delivery ◽  
High Flow ◽  
Nasal Cannula ◽  
Low Flow ◽  
Usual Practice ◽  
High Flow Oxygen ◽  
Randomised Controlled ◽  
Apnoeic Oxygenation

IntroductionApnoeic oxygenation is a process of delivering continuous oxygen through nasal cannula during direct laryngoscopy. The oxygen that is delivered through these nasal cannulas is either low flow or high flow. Although the effectiveness of apnoeic oxygenation has been shown through systematic reviews and randomised controlled trials, a comparison of high-flow versus low-flow oxygen delivery has not been tested through a superiority study design. In this study we propose to assess the effectiveness of giving low-flow oxygen with head side elevation versus high-flow oxygen with head side elevation against the usual practice of care in which no oxygen is provided during direct laryngoscopy.Methods and analysisThis will be a three-arm study instituting a block randomisation technique with a sample size of 46 in each arm (see table 1). Due to the nature of the intervention, no blinding will be introduced. The primary outcomes will be lowest non-invasive oxygen saturation measurement during direct laryngoscopy and during the 2 min after the placement of the tube and the first pass success rate. The intervention constitutes head side elevation up to 30° for improving glottis visualisation together with low-flow or high-flow oxygen delivery through nasal cannula to increase safe apnoea time for participants undergoing endotracheal intubation. Primary analysis will be intention to treat.Ethics and disseminationThe study is approved by the Ethical Review Committee of Aga Khan University Hospital (2019-0726-2463). The project is an institution University Research Committee grant recipient 192 002ER-PK. The results of the study will be disseminated among participants, patient communities and healthcare professionals in the institution through seminars, presentations and emails. Further, the findings will be published in a highly accessed peer-reviewed medical journal and will be presented at both national and international conferences.Trial registration numberClinicalTrials.gov Registry (NCT04242537).

Maximizing Oxygen Delivery During Mechanical Ventilation With a Portable Oxygen Concentrator

2010 ◽  
Vol 69 (Supplement) ◽  
pp. S87-S93 ◽  
Author(s):  
Dario Rodriquez ◽  
Thomas C. Blakeman ◽  
Warren Dorlac ◽  
Jay A. Johannigman ◽  
Richard D. Branson
Keyword(s):  
Mechanical Ventilation ◽  
Oxygen Delivery ◽  
Oxygen Concentrator ◽  
Portable Oxygen

Using a high-flow nasal cannula provided superior results to low-flow oxygen delivery in moderate to severe bronchiolitis

2016 ◽  
Vol 105 (8) ◽  
pp. e368-e372 ◽  
Author(s):  
Gregorio P. Milani ◽  
Anna M. Plebani ◽  
Elisa Arturi ◽  
Danila Brusa ◽  
Susanna Esposito ◽  
...  
Keyword(s):  
Oxygen Delivery ◽  
High Flow ◽  
Nasal Cannula ◽  
Low Flow ◽  
High Flow Nasal Cannula

Low flow oxygen delivery via nasal cannula to neonates

1996 ◽  
Vol 21 (1) ◽  
pp. 48-51 ◽  
Author(s):  
Neil N. Finer ◽  
Rosanne Bates ◽  
Paula Tomat
Keyword(s):  
Oxygen Delivery ◽  
Nasal Cannula ◽  
Low Flow

In Vitro Evaluation of a Nasal Interface Used to Improve Delivery from a Portable Oxygen Concentrator

2021 ◽  
Author(s):  
Cole Christianson ◽  
Kineshta Pillay ◽  
John Z Chen ◽  
Warren Finlay ◽  
Andrew R. Martin
Keyword(s):  
Oxygen Delivery ◽  
Nasal Airway ◽  
Quiet Breathing ◽  
Flow Rates ◽  
Delivery Modes ◽  
Oxygen Concentrator ◽  
Long Term Oxygen Therapy ◽  
Portable Oxygen

Abstract Portable oxygen concentrators (POCs) are widely used to administer long-term oxygen therapy (LTOT) and employ pulsed delivery modes to conserve oxygen. Efficient pulsed delivery requires that POCs are triggered by patient inhalation. Triggering is known to fail for some patients during periods of quite breathing, as occurs during sleep. The present article describes a new nasal interface designed to improve triggering of pulsed oxygen delivery from portable oxygen concentrators (POCs). In vitro experiments incorporating realistic nasal airway replicas and simulated breathing were conducted. The pressure monitored via oxygen supply tubing (the signal pressure) was measured over a range of constant inhalation flow rates with the nasal interface inserted into the nares of the nasal airway replicas, and compared with signal pressures measured for standard and flared nasal cannulas. Triggering efficiency and the fraction of inhaled oxygen (FiO2) were then evaluated for the nasal interface and cannulas used with a commercial POC during simulated tidal breathing through the replicas. Higher signal pressures were achieved for the nasal interface than for nasal cannulas at all flow rates studied. The nasal interface triggered pulsed delivery from the POC in cases where nasal cannulas failed to trigger. FiO2 was significantly higher for successful triggering cases than for failed triggering cases. The nasal interface improved triggering of pulsed oxygen delivery from a POC and presents a simple solution that could be used with commercially-available POCs to reliably supply oxygen during periods of quiet breathing.

scholarly journals Cold bubble humidification of low-flow oxygen does not prevent acute changes in inflammation and oxidative stress at nasal mucosa

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lauriana Alves Santana ◽  
Suellen Karoline Moreira Bezerra ◽  
Beatriz Mangueira Saraiva-Romanholo ◽  
Wellington Pereira Yamaguti ◽  
Iolanda de Fátima Lopes Calvo Tibério ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Nasal Mucosa ◽  
Oxygen Therapy ◽  
Mucociliary Clearance ◽  
Nasal Cannula ◽  
Compressed Air ◽  
Low Flow ◽  
Cross Sectional ◽  
Nasal Symptoms ◽  
Nasal Inflammation

AbstractSome clinical situations require the use of oxygen therapy for a few hours without hypoxemia. However, there are no literature reports on the effects of acute oxygen therapy on the nasal mucosa. This study aimed to evaluate the acute effects of cold bubble humidification or dry oxygen on nasal Inflammation, oxidative stress, mucociliary clearance, and nasal symptoms. This is a randomized controlled cross-sectional study in which healthy subjects were randomly allocated into four groups: (1) CA + DRY (n = 8): individuals receiving dry compressed air; (2) OX + DRY (n = 8): individuals receiving dry oxygen therapy; (3) CA + HUMID (n = 7): individuals receiving cold bubbled humidified compressed air; (4) OX + HUMID (n = 8): individuals receiving cold bubbled humidified oxygen therapy. All groups received 3 L per minute (LPM) of the oxygen or compressed air for 1 h and were evaluated: total and differential cells in the nasal lavage fluid (NLF), exhaled nitric oxide (eNO), 8-iso-PGF2α levels, saccharin transit test, nasal symptoms, and humidity of nasal cannula and mucosa. Cold bubble humidification is not able to reduced nasal inflammation, eNO, oxidative stress, mucociliary clearance, and nasal mucosa moisture. However, subjects report improvement of nasal dryness symptoms (P < 0.05). In the conclusion, cold bubble humidification of low flow oxygen therapy via a nasal cannula did not produce any effect on the nasal mucosa and did not attenuate the oxidative stress caused by oxygen. However, it was able to improve nasal symptoms arising from the use of oxygen therapy.

Assessment of the Use of Humidified Nasal Cannulas for Oxygen Therapy in Patients with Epistaxis

ORL ◽  
2021 ◽  
pp. 1-5
Author(s):  
Jingjing Liu ◽  
Tengfang Chen ◽  
Zhenggang Lv ◽  
Dezhong Wu
Keyword(s):  
Flow Rate ◽  
Oxygen Therapy ◽  
Preliminary Investigation ◽  
Nasal Cannula ◽  
Low Flow ◽  
Antiplatelet Drugs ◽  
Flow Rates ◽  
The Past ◽  
Oxygen Inhalation ◽  
Significant Difference

<b><i>Introduction:</i></b> In China, nasal cannula oxygen therapy is typically humidified. However, it is difficult to decide whether to suspend nasal cannula oxygen inhalation after the nosebleed has temporarily stopped. Therefore, we conducted a preliminary investigation on whether the use of humidified nasal cannulas in our hospital increases the incidence of epistaxis. <b><i>Methods:</i></b> We conducted a survey of 176,058 inpatients in our hospital and other city branches of our hospital over the past 3 years and obtained information concerning their use of humidified nasal cannulas for oxygen inhalation, nonhumidified nasal cannulas, anticoagulant and antiplatelet drugs, and oxygen inhalation flow rates. This information was compared with the data collected at consultation for epistaxis during these 3 years. <b><i>Results:</i></b> No significant difference was found between inpatients with humidified nasal cannulas and those without nasal cannula oxygen therapy in the incidence of consultations due to epistaxis (χ<sup>2</sup> = 1.007, <i>p</i> &#x3e; 0.05). The same trend was observed among hospitalized patients using anticoagulant and antiplatelet drugs (χ<sup>2</sup> = 2.082, <i>p</i> &#x3e; 0.05). Among the patients with an inhaled oxygen flow rate ≥5 L/min, the incidence of ear-nose-throat (ENT) consultations due to epistaxis was 0. No statistically significant difference was found between inpatients with a humidified oxygen inhalation flow rate &#x3c;5 L/min and those without nasal cannula oxygen therapy in the incidence of ENT consultations due to epistaxis (χ<sup>2</sup> = 0.838, <i>p</i> &#x3e; 0.05). A statistically significant difference was observed in the incidence of ENT consultations due to epistaxis between the low-flow nonhumidified nasal cannula and nonnasal cannula oxygen inhalation groups (χ<sup>2</sup> = 18.428, <i>p</i> &#x3c; 0.001). The same trend was observed between the 2 groups of low-flow humidified and low-flow nonhumidified nasal cannula oxygen inhalation (χ<sup>2</sup> = 26.194, <i>p</i> &#x3c; 0.001). <b><i>Discussion/Conclusion:</i></b> Neither high-flow humidified nasal cannula oxygen inhalation nor low-flow humidified nasal cannula oxygen inhalation will increase the incidence of recurrent or serious epistaxis complications; the same trend was observed for patients who use anticoagulant and antiplatelet drugs. Humidification during low-flow nasal cannula oxygen inhalation can prevent severe and repeated epistaxis to a certain extent.

Performance of different low-flow oxygen delivery systems

2021 ◽  
Author(s):  
William Poncin ◽  
Grégory Reychler ◽  
Christophe De Terwangne ◽  
Matthieu Marnette ◽  
Frédéric Duprez
Keyword(s):  
Oxygen Delivery ◽  
Delivery Systems ◽  
Low Flow
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