In Vitro Evaluation of a Nasal Interface Used to Improve Delivery from a Portable Oxygen Concentrator

2021 ◽  
Author(s):  
Cole Christianson ◽  
Kineshta Pillay ◽  
John Z Chen ◽  
Warren Finlay ◽  
Andrew R. Martin
Keyword(s):  
Oxygen Delivery ◽  
Nasal Airway ◽  
Quiet Breathing ◽  
Flow Rates ◽  
Delivery Modes ◽  
Oxygen Concentrator ◽  
Long Term Oxygen Therapy ◽  
Portable Oxygen

Abstract Portable oxygen concentrators (POCs) are widely used to administer long-term oxygen therapy (LTOT) and employ pulsed delivery modes to conserve oxygen. Efficient pulsed delivery requires that POCs are triggered by patient inhalation. Triggering is known to fail for some patients during periods of quite breathing, as occurs during sleep. The present article describes a new nasal interface designed to improve triggering of pulsed oxygen delivery from portable oxygen concentrators (POCs). In vitro experiments incorporating realistic nasal airway replicas and simulated breathing were conducted. The pressure monitored via oxygen supply tubing (the signal pressure) was measured over a range of constant inhalation flow rates with the nasal interface inserted into the nares of the nasal airway replicas, and compared with signal pressures measured for standard and flared nasal cannulas. Triggering efficiency and the fraction of inhaled oxygen (FiO2) were then evaluated for the nasal interface and cannulas used with a commercial POC during simulated tidal breathing through the replicas. Higher signal pressures were achieved for the nasal interface than for nasal cannulas at all flow rates studied. The nasal interface triggered pulsed delivery from the POC in cases where nasal cannulas failed to trigger. FiO2 was significantly higher for successful triggering cases than for failed triggering cases. The nasal interface improved triggering of pulsed oxygen delivery from a POC and presents a simple solution that could be used with commercially-available POCs to reliably supply oxygen during periods of quiet breathing.

Maximizing Oxygen Delivery During Mechanical Ventilation With a Portable Oxygen Concentrator

2010 ◽  
Vol 69 (Supplement) ◽  
pp. S87-S93 ◽  
Author(s):  
Dario Rodriquez ◽  
Thomas C. Blakeman ◽  
Warren Dorlac ◽  
Jay A. Johannigman ◽  
Richard D. Branson
Keyword(s):  
Mechanical Ventilation ◽  
Oxygen Delivery ◽  
Oxygen Concentrator ◽  
Portable Oxygen

Burden and Unmet Needs with Portable Oxygen in Patients on Long Term Oxygen Therapy

2021 ◽  
Author(s):  
Jessica Dakkak ◽  
Wilson Tang ◽  
Jonathan T Smith ◽  
Aparna Balasubramanian ◽  
Moriah Mattson ◽  
...  
Keyword(s):  
Oxygen Therapy ◽  
Unmet Needs ◽  
Long Term Oxygen Therapy ◽  
Portable Oxygen

scholarly journals Comparison of Nasal Cannulas and the OxyArm in Patients Requiring Chronic Domiciliary Oxygen Therapy

2006 ◽  
Vol 13 (8) ◽  
pp. 421-426 ◽  
Author(s):  
James Paul ◽  
Ted Otvos
Keyword(s):  
Oxygen Delivery ◽  
Oxygen Therapy ◽  
Outpatient Setting ◽  
Chronic Obstructive ◽  
Walk Test ◽  
Obstructive Pulmonary Disease ◽  
Current Design ◽  
Long Term Oxygen Therapy ◽  
Randomized Crossover Study

OBJECTIVES: The present study was designed to compare the performance of a new oxygen delivery device, the OxyArm (OA) (Southmedic Inc, Canada), with a standard nasal cannula (NC) (Salter-Style 1600, Salter Labs, USA) for both oxygen delivery and patient preference in patients on long-term oxygen therapy (LTOT).DESIGN AND SETTING: Randomized crossover study conducted in an outpatient setting.PATIENTS AND METHODS: Twenty-five clinically stable LTOT patients were randomly assigned to an oxygen device (NC or OA) sequence. The baseline saturation level was determined, and patients were then treated at oxygen flow rates of 2 L/min, 3 L/min, 4 L/min, 5 L/min, 6 L/min and 7 L/min for 10 min each while at rest. Patients were then crossed over to the second device and the procedure was repeated. Oximetry values were then obtained following a 5 min walk test using the same device sequence. Lastly, the patients were sent home for a four-week home OA trial, after which, they filled out a questionnaire.RESULTS: This sample of patients was primarily elderly ex-smokers with severe chronic obstructive pulmonary disease on oxygen therapy for the majority of the day. The primary findings were that the OA and NC were equally effective in delivering oxygen to patients and maintaining their oxygen saturation at both rest (P=0.82) and during a 5 min walk test (P=0.83). A patient’s personal experience and comfort were identified as the most important factors in deciding on an oxygen device. Most patients felt that the OA was most suited for oxygen therapy while at rest.CONCLUSIONS: The OA proved to be similar to the NC in delivering oxygen and maintaining saturation in patients on LTOT. The OA is one of the few alternatives to using NCs for these patients and, with its current design, appears to be most suited for resting conditions.

scholarly journals In Vitro–In Silico Comparison of Pulsed Oxygen Delivery From Portable Oxygen Concentrators Versus Continuous Flow Oxygen Delivery

2019 ◽  
Vol 64 (2) ◽  
pp. 117-129 ◽  
Author(s):  
John Z Chen ◽  
Ira M Katz ◽  
Marine Pichelin ◽  
Kaixian Zhu ◽  
Georges Caillibotte ◽  
...  
Keyword(s):  
Oxygen Delivery ◽  
In Silico ◽  
Continuous Flow ◽  
Portable Oxygen

scholarly journals Five-year experience in providing medical care to patients with bronchopulmonary pathology with chronic hypoxemic respiratory failure

2020 ◽  
Vol 64 (3) ◽  
pp. 117-123
Author(s):  
Olga N. Titova ◽  
Natalia A. Kuzubova ◽  
Vladimir A. Volchkov ◽  
Andrey G. Kozyrev ◽  
Darya B. Skljarova
Keyword(s):  
Respiratory Failure ◽  
Medical Care ◽  
First Year ◽  
Hypoxemic Respiratory Failure ◽  
Copd Patients ◽  
Oxygen Concentrator ◽  
Second Year ◽  
To Receive ◽  
Long Term Oxygen Therapy

Introduction. The article considers the management of medical care for patients with chronic hypoxemic respiratory failure (CHRF), including long-term oxygen therapy (LOT). To achieve this goal in 2013 there was established the St. Petersburg Municipal Pulmonary Center (MPC). The study aimed to assess the results of the MPC activity in 2014 - 2LC138727590CN018. Material and methods. The medical records of patients admitted to the MPC in 2014-2018 were studied. To process the information conventional statistical methods were used. Results. Over the past 5 years, MRC specialists have consulted 13,239 patients, mainly COPD cases. 1,054 patients with CHRF were hospitalized for an additional examination, and 435 cases were indicated to receive LOT. The necessary oxygen concentrator facilities were provided at the expense of the St. Petersburg city budget. Mortality rate accounted for 10.4% by the end of the first year of LOT, 15.1% by the end of the second year, reaching 27.0% and 38.3% by the end of the third and fourth years, respectively. In the group of COPD patients with CHRF (262 patients, 238 men, and 24 women, at the average age of 69 ± 3 years), LOT was accompanied by a decrease in the number of severe exacerbations of the disease (before the LOT - 3 (3; 4) severe exacerbations per year, after a year - 2 (1; 2); p <0.001), as well as cases of referral and duration of stay in the intensive care unit. This led to a decrease in the average cost of inpatient treatment from 264,912 ± 31,277 rubles per year to 134,826 ± 21,277; p <0.001. Conclusion. Early verification and correction of CHRF contribute not only to the decline in the number of exacerbations of respiratory disease but also to the reduction of financial costs necessary for the treatment of such patients.

Clinical evaluation of long-term use of a portable oxygen concentrator capable of operating under car battery power

2002 ◽  
Vol 2 (2) ◽  
pp. 110-114
Author(s):  
Daisuke Fuse ◽  
Takaaki Nakamoto ◽  
Hiroshi Harasawa ◽  
Suguru Machida ◽  
Hirohisa Amano ◽  
...  
Keyword(s):  
Clinical Evaluation ◽  
Battery Power ◽  
Oxygen Concentrator ◽  
Portable Oxygen
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