scholarly journals Chest Wall Mobility Is Related to Respiratory Muscle Strength and Lung Volumes in Healthy Subjects

2013 ◽  
Vol 58 (12) ◽  
pp. 2107-2112 ◽  
Author(s):  
F. d. C. Lanza ◽  
A. A. de Camargo ◽  
L. R. F. Archija ◽  
J. P. R. Selman ◽  
C. Malaguti ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Chest Wall ◽  
Healthy Subjects ◽  
Respiratory Muscle ◽  
Respiratory Muscle Strength ◽  
Lung Volumes ◽  
Wall Mobility

Lung volumes and respiratory muscle strength in adult patients with childhood- or adult-onset growth hormone deficiency: effect of 12 months' growth hormone replacement therapy

1996 ◽  
Vol 135 (5) ◽  
pp. 553-558 ◽  
Author(s):  
Bartolomeo Merola ◽  
Salvatore Longobardi ◽  
Matteo Sofia ◽  
Rosario Pivonello ◽  
Assunta Micco ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Muscle Strength ◽  
Healthy Subjects ◽  
Respiratory Muscle ◽  
Gh Deficiency ◽  
Adult Patients ◽  
Respiratory Muscle Strength ◽  
Adult Onset ◽  
Childhood Onset ◽  
Lung Volumes

Merola B, Longobardi S, Sofia M, Pivonello R, Micco A, Di Rella F, Esposito V, Colao A, Lombardi G. Lung volumes and respiratory muscle strength in adult patients with childhood- or adult-onset growth hormone deficiency. Effect of 12 months' growth hormone replacement therapy. Eur J Endocrinol 1996;135:553–8. ISSN 0804–4643 We have described impairment of the respiratory function in adult patients with childhood-onset growth hormone (GH) deficiency. The aim of the present study was to evaluate lung volumes and respiratory muscle strength in patients diagnosed as GH deficient before and after 6 and 12 months of recombinant GH treatment. Ten adults diagnosed as GH deficient in childhood, ten adults diagnosed as GH deficient in adulthood and ten healthy subjects entered the study. For each subject, evaluation of respiratory function followed the same standard approach, consisting of respiratory muscle strength assessment, record of flow–volume curves, measurement of static lung volumes and lung diffusing capacity. Childhood-onset GH-deficient patients had a significant reduction of maximal inspiratory (p < 0.01) and maximal expiratory (p < 0.05) mouth pressures. Total lung capacity, vital capacity and functional residual capacity were significantly reduced compared to healthy subjects (p < 0.05). Conversely, residual volume and diffusing lung capacity did not show any significant change. No significant change of the ratio between the percentage forced expiratory volume in 1 s and the forced vital capacity was observed. The decrease of respiratory mouth pressures was not correlated to the decrease of lung volumes. Adult-onset GH-deficient patients had only a significant reduction of maximal expiratory pressure compared to healthy subjects (p < 0.05). After 6 months of treatment no significant differences in any of the evaluated parameters were found. After 12 months of treatment patients with childhood-onset GH deficiency show a significant improvement of lung volumes (p < 0.01) and maximal respiratory mouth pressures (p < 0.005), whereas adult-onset GH-deficient patients show a significant improvement of maximal expiratory pressure (p < 0.05). In conclusion, the results of this study showed that adult patients affected with childhood-onset GH deficiency suffer from an impairment of the ventilatory function due to a reduction of lung volumes and a decrease of respiratory pressures probably due to a reduction of respiratory muscle strength. This impairment was reversed after 12 months of treatment with recombinant GH. Conversely, adult-onset GH-deficient patients had only an impairment of the maximal expiratory pressure, probably due to respiratory muscle weakness re-established after 12 months of GH therapy. Gaetano Lombardi, Via G. Santacroce 40/a, 80129 Naples, Italy

scholarly journals Impact of thoracic radiotherapy on respiratory function and exercise capacity in patients with breast cancer

2018 ◽  
Vol 44 (6) ◽  
pp. 469-476 ◽  
Author(s):  
Milena Mako Suesada ◽  
Heloisa de Andrade Carvalho ◽  
André Luis Pereira de Albuquerque ◽  
João Marcos Salge ◽  
Silvia Radwanski Stuart ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Muscle Strength ◽  
Chest Wall ◽  
Exercise Capacity ◽  
Respiratory Function ◽  
Respiratory Muscle ◽  
Radiation Pneumonitis ◽  
Respiratory Muscle Strength ◽  
Thoracic Radiotherapy ◽  
Wall Mobility

ABSTRACT Objective: To evaluate the impact of thoracic radiotherapy on respiratory function and exercise capacity in patients with breast cancer. Methods: Breast cancer patients in whom thoracic radiotherapy was indicated after surgical treatment and chemotherapy were submitted to HRCT, respiratory evaluation, and exercise capacity evaluation before radiotherapy and at three months after treatment completion. Respiratory muscle strength testing, measurement of chest wall mobility, and complete pulmonary function testing were performed for respiratory evaluation; cardiopulmonary exercise testing was performed to evaluate exercise capacity. The total radiotherapy dose was 50.4 Gy (1.8 Gy/fraction) to the breast or chest wall, including supraclavicular lymph nodes (SCLN) or not. Dose-volume histograms were calculated for each patient with special attention to the ipsilateral lung volume receiving 25 Gy (V25), in absolute and relative values, and mean lung dose. Results: The study comprised 37 patients. After radiotherapy, significant decreases were observed in respiratory muscle strength, chest wall mobility, exercise capacity, and pulmonary function test results (p < 0.05). DLCO was unchanged. HRCT showed changes related to radiotherapy in 87% of the patients, which was more evident in the patients submitted to SCLN irradiation. V25% significantly correlated with radiation pneumonitis. Conclusions: In our sample of patients with breast cancer, thoracic radiotherapy seemed to have caused significant losses in respiratory and exercise capacity, probably due to chest wall restriction; SCLN irradiation represented an additional risk factor for the development of radiation pneumonitis.

scholarly journals Monitoring respiratory muscle strength assists in early diagnosis of respiratory dysfunction as opposed to the isolated use of pulmonary function evaluation in amyotrophic lateral sclerosis

2013 ◽  
Vol 71 (3) ◽  
pp. 146-152 ◽  
Author(s):  
Guilherme Fregonezi ◽  
Palomma Russelly Saldanha Araújo ◽  
Tathiana Lindemberg Ferreira Macêdo ◽  
Mario Emilio Dourado Junior ◽  
Vanessa Regiane Resqueti ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Muscle Strength ◽  
Early Diagnosis ◽  
Pulmonary Function ◽  
Healthy Subjects ◽  
Respiratory Muscle ◽  
Function Evaluation ◽  
Respiratory Muscle Strength ◽  
Respiratory Dysfunction ◽  
Lateral Sclerosis

ObjectiveIt was study the relationship between respiratory muscle strength and forced vital capacity (FVC) in patients with amyotrophic lateral sclerosis (ALS) versus healthy subjects.MethodsPulmonary function and respiratory muscle strength [maximal inspiratory (PImax), maximal expiratory (PEmax) and sniff nasal inspiratory pressure (SNIP)] were assessed in patients with ALS and healthy subjects, matched using cutoffs established in the literature for impaired pulmonary function and respiratory muscle weakness.ResultsTwenty-eight ALS patients and 28 healthy subjects were studied. We found sensitivity and specificity for PImax, PEmax and SNIP of 75/58%, 81/67% and 75/67%. The Receiver Operating Characteristic curve (ROC curve) indicated that the variables PImax, PEmax and SNIP can identify differences in respiratory muscle strength between ALS and healthy individuals at 0.89, 0.9 and 0.82, respectively. A positive correlation was recorded between FVC (%) versus SNIP, PImax and PEmax.ConclusionIn ALS, monitoring respiratory muscle strength assists in early diagnosis of respiratory dysfunction as opposed to the isolated use of FVC.

Respiratory muscle strength at rest, during and after maximal exercise in healthy subjects

2015 ◽  
Author(s):  
Letícia Zumpano Cardenas ◽  
Pauliane Vieira Santana ◽  
Mayra Caleffi Pereira ◽  
Jeferson George Ferreira ◽  
Luiz Fernando Orlandin ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Healthy Subjects ◽  
Respiratory Muscle ◽  
Maximal Exercise ◽  
Respiratory Muscle Strength

scholarly journals Pulmonary Function after Weight Loss in Obese Women Undergoing Roux-en-Y Gastric Bypass: One-Year Followup

ISRN Obesity ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Marcela Cangussu Barbalho-Moulim ◽  
Gustavo Peixoto Soares Miguel ◽  
Eli Maria Pazzianotto Forti ◽  
Flávio do Amaral Campos ◽  
Fabiana Sobral Peixoto-Souza ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Gastric Bypass ◽  
Muscle Strength ◽  
Respiratory Muscle ◽  
Gastric Bypass Surgery ◽  
Respiratory Muscle Strength ◽  
Obese Women ◽  
Lung Volumes ◽  
One Year

Introduction. Obesity is a condition that causes damage to the respiratory function. However, studies have demonstrated that weight loss due to bariatric surgery has resulted in a huge improvement on some lung volumes, but controversy still persists regarding the behavior of the respiratory muscle strength and IRV (inspiratory reserve volume). Objective. To evaluate the effect of weight loss, after 1 year of the Roux-en-Y gastric bypass surgery (RYGB), on the lung volumes and the respiratory muscle strength in obese women. Methods. 24 obese women candidates were recruited for RYGB. Lung volumes (spirometry) and respiratory muscle strength were evaluated in preoperative period and one year after surgery. Results. There was a significant increase in some lung volumes. However, when examining the components of the VC (vital capacity) separately, an increase in ERV (expiratory reserve volume) and reduction of IRV were observed. Moreover, a statistically significant reduction in the values of respiratory muscle strength was recorded: MIP (maximal inspiratory pressure) and MEP (maximal expiratory pressure). Conclusion. Weight loss induced by bariatric surgery provides an increase in some lung volumes of obese women, but reduction in IRV. Additionally, there was also a reduction in the respiratory muscle strength.

Chest wall pain and related respiratory muscle strength in patients with primary fibromyalgia

2002 ◽  
Vol 14 (3) ◽  
pp. 201-205
Author(s):  
Günşah Şahin ◽  
Bahar Ulubaş ◽  
Selda Bağiş ◽  
Mukadder Çalikoğlu ◽  
Yasemin Yapici ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Chest Wall ◽  
Respiratory Muscle ◽  
Respiratory Muscle Strength ◽  
Primary Fibromyalgia

Impairment of lung volumes and respiratory muscle strength in adult patients with growth hormone deficiency

1995 ◽  
Vol 133 (6) ◽  
pp. 680-685 ◽  
Author(s):  
Bartolomeo Merola ◽  
Matteo Sofia ◽  
Salvatore Longobardi ◽  
Serafino Fazio ◽  
Assunta Micco ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Muscle Strength ◽  
Respiratory Muscle ◽  
Vital Capacity ◽  
Gh Deficiency ◽  
Adult Patients ◽  
Hormone Deficiency ◽  
Respiratory Muscle Strength ◽  
Lung Volumes ◽  
Lung Capacity

Merola B, Sofia M, Longobardi S, Fazio S, Micco A, Esposito V, Colao A, Biondi B, Lombardi G. Impairment of lung volumes and respiratory muscle strength in adult patients with growth hormone deficiency. Eur J Endocrinol 1995;133:680–5. ISSN 0804–4643 Little is known of the respiratory function in patients with growth hormone (GH) deficiency. The aim of the present study was to evaluate lung volumes and respiratory muscle strength in patients diagnosed as GH deficient in childhood. Ten patients diagnosed as GH deficient in childhood and ten healthy subjects entered the study. For each subject the evaluation of respiratory function followed the same standard approach, consisting of respiratory muscle strength assessment, recording of flowvolume curves, measurement of static lung volumes and lung diffusing capacity. Both maximal inspiratory and expiratory mouth pressures were decreased in GH deficiency. Vital capacity, N2 functional residual capacity and total lung capacity were significantly reduced when compared to healthy subjects. Conversely, the residual volume and diffusing lung capacity to CO did not show any significant change. No significant change of percentage forced expiratory volume in 1 s/forced vital capacity ratio was observed. The decrease of respiratory mouth pressures was not correlated to the decrease of lung volumes. In conclusion, the results of this study show that adult patients affected with childhood onset GH deficiency suffer from impairment of ventilatory function and a decrease of respiratory muscle pressures, probably due to reduction of respiratory muscle strength. Gaetano Lombardi, Via G Santacroce 40/1, 80 129 Naples, Italy

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