Bioavailability of Two Oral-Suspension Formulations of a Single Dose of Nitazoxanide 500 mg: An Open-Label, Randomized-Sequence, Two-Period Crossover, Comparison in Healthy Fasted Mexican Adult Volunteers

2011 ◽  
Vol 03 (03) ◽  
Author(s):  
Juana Isabel Balderas-Acata ◽  
Esteban Patricio Ríos-Rogríguez ◽  
Bueno Fabiola Pérez-Becerril
Keyword(s):  
Single Dose ◽  
Oral Suspension ◽  
Open Label ◽  
Adult Volunteers ◽  
Crossover Comparison

Bioavailability of Two Single-Dose Oral Formulations of Omeprazole 20 mg: An Open-Label, Randomized Sequence, Two-Period Crossover Comparison in Healthy Mexican Adult Volunteers

2008 ◽  
Vol 30 (4) ◽  
pp. 693-699 ◽  
Author(s):  
Jorge Luis Poo ◽  
Juan Francisco Galán ◽  
Alejandra Rosete ◽  
Alberto de Lago ◽  
Iván Oliva ◽  
...  
Keyword(s):  
Single Dose ◽  
Open Label ◽  
Oral Formulations ◽  
Dose Oral ◽  
Adult Volunteers ◽  
Crossover Comparison

Bioavailability of Two Coated-Tablet Formulations of a Single Dose of Pantoprazole 40 mg: An Open-Label, Randomized, Two-Period Crossover, Comparison in Healthy Mexican Adult Volunteers

2011 ◽  
Vol 03 (05) ◽  
Author(s):  
Juana Isabel Balderas-Acata ◽  
Esteban Patricio Ríos- Rogríguez Bueno ◽  
Sofía del Castillo-García ◽  
Clara Espinosa- Martínez, ◽  
Victoria Burke-Fraga
Keyword(s):  
Single Dose ◽  
Open Label ◽  
Coated Tablet ◽  
Tablet Formulations ◽  
Adult Volunteers ◽  
Crossover Comparison

Bioavailability of two sublingual formulations of ketorolac tromethamine 30 mg: A randomized, open-label, single-dose, two-period crossover comparison in healthy mexican adult volunteers

2008 ◽  
Vol 30 (9) ◽  
pp. 1667-1674 ◽  
Author(s):  
Juan Francisco Galán-Herrera ◽  
Jorge Luis Poo ◽  
Jose Alfonso Maya-Barrios ◽  
Alberto de Lago ◽  
Iván Oliva ◽  
...  
Keyword(s):  
Single Dose ◽  
Ketorolac Tromethamine ◽  
Open Label ◽  
Adult Volunteers ◽  
Crossover Comparison

A Single-Dose, Two-Way Crossover, Open-Label Bioequivalence Study of an Amphetamine Extended-Release Oral Suspension in Healthy Adults

2017 ◽  
Vol 24 (3) ◽  
pp. 414-419 ◽  
Author(s):  
Carolyn Sikes ◽  
Jeffrey G. Stark ◽  
Russ McMahen ◽  
Dorothy Engelking
Keyword(s):  
Single Dose ◽  
Extended Release ◽  
Healthy Adult ◽  
Bioequivalence Study ◽  
Oral Suspension ◽  
Pharmacokinetic Parameters ◽  
Open Label ◽  
Adult Participants ◽  
Study Results ◽  
Adult Volunteers

Objective: The purpose of this study was to compare the pharmacokinetics of a new extended-release amphetamine oral suspension (AMP XR-OS) with a standard extended-release mixed amphetamine salts product, Adderall XR®. Method: In this single-dose, open-label, randomized, two-period, two-treatment crossover study, 42 healthy adult volunteers received 15 mL of AMP XR-OS in one period and a 30 mg Adderall XR capsule in another period (both containing 18.8 mg of amphetamine base) under fasted conditions. Blood samples were analyzed for d- and l-amphetamine concentrations, and pharmacokinetic parameters Cmax, AUC0-5, AUC5-last, and AUCinf were calculated to determine bioequivalence. Safety was monitored throughout the study. Results: The 90% confidence intervals (CIs) for the log-transformed Cmax, AUC0-5, AUC5-last, and AUCinf fell within the accepted 80% to 125% range for establishing bioequivalence for d- and l-amphetamine. The most common adverse events were nausea and decreased appetite. Conclusion: AMP XR-OS is bioequivalent to Adderall XR in healthy adult participants.

Relative bioavailability of two oral formulations of piroxicam 20 mg: A single-dose, randomized-sequence, open-label, two-period crossover comparison in healthy Mexican adult volunteers

2010 ◽  
Vol 32 (2) ◽  
pp. 357-364 ◽  
Author(s):  
Jose Antonio Palma-Aguirre ◽  
Mireya Lopez-Gamboa ◽  
Lizbeth Cariño ◽  
Victoria Burke-Fraga ◽  
Mario González-de la Parra
Keyword(s):  
Single Dose ◽  
Relative Bioavailability ◽  
Open Label ◽  
Oral Formulations ◽  
Adult Volunteers ◽  
Crossover Comparison

Bioavailability of two oral-tablet and two oral-suspension formulations of naproxen sodium/paracetamol (acetaminophen): Single-dose, randomized, open-label, two-period crossover comparisons in healthy Mexican adult subjects

2009 ◽  
Vol 31 (2) ◽  
pp. 399-410 ◽  
Author(s):  
Jose Antonio Palma-Aguirre ◽  
Jorge Villalpando-Hernández ◽  
Germán Novoa-Heckel ◽  
Iván Oliva ◽  
Lizbeth Cariño ◽  
...  
Keyword(s):  
Single Dose ◽  
Naproxen Sodium ◽  
Oral Suspension ◽  
Open Label ◽  
Oral Tablet
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