scholarly journals Bioequivalence of Two Oral Tablet Formulations of Betahistine 24 Mg: Single-Dose, Open-Label, Randomized, Two-Period Crossover Comparison in Healthy Individuals

2015 ◽  
Vol 07 (01) ◽  
Author(s):  
Larisa Estrada Beatriz Cedillo
Keyword(s):  
Single Dose ◽  
Healthy Individuals ◽  
Open Label ◽  
Oral Tablet ◽  
Tablet Formulations ◽  
Crossover Comparison

Bioavailability of Two Coated-Tablet Formulations of a Single Dose of Pantoprazole 40 mg: An Open-Label, Randomized, Two-Period Crossover, Comparison in Healthy Mexican Adult Volunteers

2011 ◽  
Vol 03 (05) ◽  
Author(s):  
Juana Isabel Balderas-Acata ◽  
Esteban Patricio Ríos- Rogríguez Bueno ◽  
Sofía del Castillo-García ◽  
Clara Espinosa- Martínez, ◽  
Victoria Burke-Fraga
Keyword(s):  
Single Dose ◽  
Open Label ◽  
Coated Tablet ◽  
Tablet Formulations ◽  
Adult Volunteers ◽  
Crossover Comparison

Bioavailability of two oral suspension and two oral tablet formulations of acyclovir 400 mg: Two single-dose, open-label, randomized, two-period crossover comparisons in healthy Mexican adult subjects

2007 ◽  
Vol 29 (6) ◽  
pp. 1146-1152 ◽  
Author(s):  
Jose Antonio Palma-Aguirre ◽  
Jose Antonio Absalón-Reyes ◽  
Germán Novoa-Heckel ◽  
Alberto de Lago ◽  
Iván Oliva ◽  
...  
Keyword(s):  
Single Dose ◽  
Oral Suspension ◽  
Open Label ◽  
Oral Tablet ◽  
Tablet Formulations

Bioavailability of Two Single-Dose Oral Formulations of Omeprazole 20 mg: An Open-Label, Randomized Sequence, Two-Period Crossover Comparison in Healthy Mexican Adult Volunteers

2008 ◽  
Vol 30 (4) ◽  
pp. 693-699 ◽  
Author(s):  
Jorge Luis Poo ◽  
Juan Francisco Galán ◽  
Alejandra Rosete ◽  
Alberto de Lago ◽  
Iván Oliva ◽  
...  
Keyword(s):  
Single Dose ◽  
Open Label ◽  
Oral Formulations ◽  
Dose Oral ◽  
Adult Volunteers ◽  
Crossover Comparison

Bioavailability of two oral-tablet and two oral-suspension formulations of naproxen sodium/paracetamol (acetaminophen): Single-dose, randomized, open-label, two-period crossover comparisons in healthy Mexican adult subjects

2009 ◽  
Vol 31 (2) ◽  
pp. 399-410 ◽  
Author(s):  
Jose Antonio Palma-Aguirre ◽  
Jorge Villalpando-Hernández ◽  
Germán Novoa-Heckel ◽  
Iván Oliva ◽  
Lizbeth Cariño ◽  
...  
Keyword(s):  
Single Dose ◽  
Naproxen Sodium ◽  
Oral Suspension ◽  
Open Label ◽  
Oral Tablet

Bioequivalence of two film-coated tablets of imatinib mesylate 400 mg: A randomized, open-label, single-dose, fasting, two-period, two-sequence crossover comparison in healthy male South American volunteers

2009 ◽  
Vol 31 (10) ◽  
pp. 2224-2232 ◽  
Author(s):  
Susana Parrillo-Campiglia ◽  
Mónica Cedres Ercoli ◽  
Ofelia Umpierrez ◽  
Patricia Rodríguez ◽  
Sara Márquez ◽  
...  
Keyword(s):  
Single Dose ◽  
Imatinib Mesylate ◽  
South American ◽  
Healthy Male ◽  
Open Label ◽  
Crossover Comparison

Single Dose Pharmacokinetics of Metoclopramide Oral Tablets Utilizing HPLC-UV Method

2019 ◽  
Vol 15 (7) ◽  
pp. 703-709 ◽  
Author(s):  
Iram Kaukab ◽  
Syed Nisar Hussain Shah ◽  
Ghulam Murtaza
Keyword(s):  
Single Dose ◽  
Area Under Curve ◽  
Oral Formulation ◽  
Gastrointestinal Disorders ◽  
Published Data ◽  
Maximum Plasma ◽  
Open Label ◽  
Oral Tablet ◽  
Blood Samples ◽  
Healthy Males

Background: Metoclopramide is a potent dopaminergic antagonist utilized for treating gastrointestinal disorders. The aim of this study was to examine the pharmacokinetics of oral formulation of metoclopramide in the Pakistani volunteers. Methods: This open label, single dose, pharmacokinetic study was executed in non-smoking, 12 Pakistani healthy males, treated with a single 20 mg oral tablet dose of metoclopramide on test day. Maximum plasma concentration (Cmax), time to achieve Cmax (Tmax), and area under curve (AUC0-t) of metoclopramide were determined analyzing the serial blood samples using a validated HPLC-UV method. Results: The determined values of Cmax, Tmax, and AUC0-t of metoclopramide were 34.51 ± 4.91 ng/ml, 1.56 ± 0.18 and 273.88 ± 114.49 ng.h/ml, respectively. Conclusion: The results reveal that the findings of Pakistani individuals are slightly different when compared with the published data of other ethnic origins.

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