scholarly journals Retinoic acid-producing DCs and gut-tropic FOXP3+regulatory T cells in the induction of oral tolerance

2013 ◽  
Vol 2 (2) ◽  
pp. e22987 ◽  
Author(s):  
Eduardo J. Villablanca
Keyword(s):  
T Cells ◽  
Retinoic Acid ◽  
Regulatory T Cells ◽  
Oral Tolerance

scholarly journals Oral tolerance: is it all retinoic acid?

2007 ◽  
Vol 204 (8) ◽  
pp. 1737-1739 ◽  
Author(s):  
Harald von Boehmer
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Retinoic Acid ◽  
Growth Factor ◽  
Vitamin A ◽  
Oral Tolerance ◽  
Transforming Growth Factor ◽  
Tolerance Mechanisms ◽  
Cell Homing ◽  
Naïve T Cells

Oral tolerance has been argued to depend on “special” presentation of antigen in the gut. New studies support this idea by showing that the catalysis of vitamin A into retinoic acid (RA) in gut-associated dendritic cells (DCs) enhances the transforming growth factor (TGF)-β–dependent conversion of naive T cells into regulatory T (T reg) cells and also directs T reg cell homing to the gut. These results reveal new tolerance mechanisms that will aid the use of T reg cells in the clinic.

522 Retinoic Acid Controlled Cyclooxygenase-2 Mediates Induction of Regulatory T-Cells in the Intestine

2008 ◽  
Vol 134 (4) ◽  
pp. A-73-A-74
Author(s):  
Femke Broere ◽  
M. Fleur du Pré ◽  
Lisette van Berkel ◽  
Bart Lambrecht ◽  
Rudolf W. Hendriks ◽  
...  
Keyword(s):  
T Cells ◽  
Retinoic Acid ◽  
Regulatory T Cells ◽  
Cyclooxygenase 2

scholarly journals Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells

2014 ◽  
Vol 8 (2) ◽  
pp. 265-278 ◽  
Author(s):  
G Bakdash ◽  
L TC Vogelpoel ◽  
T MM van Capel ◽  
M L Kapsenberg ◽  
E C de Jong
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Retinoic Acid ◽  
Regulatory T Cells ◽  
Human Dendritic Cells

scholarly journals Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection

2014 ◽  
Vol 45 (2) ◽  
pp. 452-463 ◽  
Author(s):  
Carolina Moore ◽  
Gabriela Tejon ◽  
Camila Fuentes ◽  
Yessia Hidalgo ◽  
Maria R. Bono ◽  
...  
Keyword(s):  
T Cells ◽  
Retinoic Acid ◽  
Regulatory T Cells ◽  
Allograft Rejection ◽  
Skin Allograft

scholarly journals Single and combined effect of retinoic acid and rapamycin modulate the generation, activity and homing potential of induced human regulatory T cells

PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0182009 ◽  
Author(s):  
Enzo Candia ◽  
Paz Reyes ◽  
Camila Covian ◽  
Francisco Rodriguez ◽  
Nicolas Wainstein ◽  
...  
Keyword(s):  
T Cells ◽  
Retinoic Acid ◽  
Regulatory T Cells ◽  
Combined Effect ◽  
Generation Activity

scholarly journals Differential role of all-trans retinoic acid in promoting the development of CD4+ and CD8+ regulatory T cells

2013 ◽  
Vol 95 (2) ◽  
pp. 275-283 ◽  
Author(s):  
Jilin Ma ◽  
Ya Liu ◽  
Yang Li ◽  
Jian Gu ◽  
Justin Liu ◽  
...  
Keyword(s):  
T Cells ◽  
Retinoic Acid ◽  
Regulatory T Cells ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid
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