scholarly journals Low immunogenicity predicted for emerging avian-origin H7N9

2013 ◽  
Vol 9 (5) ◽  
pp. 950-956 ◽  
Author(s):  
Anne S. De Groot ◽  
Matthew Ardito ◽  
Frances Terry ◽  
Lauren Levitz ◽  
Ted Ross ◽  
...  
Keyword(s):  
Avian Origin

Rapid hemagglutinin subtyping of novel avian-origin influenza A(H7N9) virus using a diagnostic microarray

2014 ◽  
Vol 8 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Dong-Hun Lee ◽  
Ji-Hoon Kim ◽  
Seong-Su Yuk ◽  
Jung-Hoon Kwon ◽  
Hyunseok Cho ◽  
...  
Keyword(s):  
Influenza A ◽  
H7n9 Virus ◽  
Avian Origin

Identification and genetic characterization of avian-origin H3N2 canine influenza viruses isolated from the Liaoning province of China in 2012

Virus Genes ◽  
2014 ◽  
Vol 49 (2) ◽  
pp. 342-347 ◽  
Author(s):  
Xinyan Yang ◽  
Chunguo Liu ◽  
Fei Liu ◽  
Dafei Liu ◽  
Yan Chen ◽  
...  
Keyword(s):  
Genetic Characterization ◽  
Influenza Viruses ◽  
Liaoning Province ◽  
Avian Origin ◽  
Canine Influenza

scholarly journals Molecular Diversity and Genetic Relatedness of Candida albicans Isolates from Birds in Hungary

2021 ◽  
Vol 186 (2) ◽  
pp. 237-244
Author(s):  
M. Domán ◽  
L. Makrai ◽  
Gy. Lengyel ◽  
R. Kovács ◽  
L. Majoros ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Molecular Diversity ◽  
Genetic Relatedness ◽  
Group Method ◽  
Pair Group ◽  
Degree Of Separation ◽  
Avian Origin ◽  
Species Specific ◽  
Sequence Types ◽  
Unweighted Pair Group Method

AbstractThe molecular epidemiology of Candida albicans infections in animals has been rarely studied. In this study, multilocus sequence typing was used to characterise the genetic diversity and population structure of 24 avian origin C. albicans isolates collected from different birds with candidiasis and compared to human isolates. Fourteen diploid sequence types (DSTs) including six new DSTs were determined. Cluster analysis revealed that isolates grouped into 8 clades. Bird isolates mainly belonged to minor clades and Clade 15 with DST 172 was the most common (11 isolates; 45.8%). The remaining isolates were clustered into Clade 7 (5 isolates; 20.8%), Clade 10 (4 isolates; 16.6%), Clade 8 (2 isolates; 8.3%), Clade 4 (1 isolate; 4.2%) and Clade 16 (1 isolate; 4.2%). Unweighted pair group method with arithmetic averages (UPGMA) and eBURST analyses showed that the genetic construction of avian origin C. albicans population is fairly diverse. Although species-specific lineages were not found, some degree of separation in the evolution of bird and human strains could be observed.

scholarly journals Severe human infection with a novel avian-origin influenza A(H7N4) virus

2018 ◽  
Vol 63 (16) ◽  
pp. 1043-1050 ◽  
Author(s):  
Xiang Huo ◽  
Lun-biao Cui ◽  
Cong Chen ◽  
Dayan Wang ◽  
Xian Qi ◽  
...  
Keyword(s):  
Influenza A ◽  
Human Infection ◽  
Avian Origin

scholarly journals Evolution and Adaptation of the Avian H7N9 Virus into the Human Host

2020 ◽  
Vol 8 (5) ◽  
pp. 778
Author(s):  
Andrew T. Bisset ◽  
Gerard F. Hoyne
Keyword(s):  
Amino Acid ◽  
Avian Influenza ◽  
Influenza A ◽  
Amino Acid Sequences ◽  
Influenza Viruses ◽  
Amino Acid Substitutions ◽  
Upper Respiratory Tract ◽  
Viral Polymerase ◽  
Evolutionary Changes ◽  
Avian Origin

Influenza viruses arise from animal reservoirs, and have the potential to cause pandemics. In 2013, low pathogenic novel avian influenza A(H7N9) viruses emerged in China, resulting from the reassortment of avian-origin viruses. Following evolutionary changes, highly pathogenic strains of avian influenza A(H7N9) viruses emerged in late 2016. Changes in pathogenicity and virulence of H7N9 viruses have been linked to potential mutations in the viral glycoproteins hemagglutinin (HA) and neuraminidase (NA), as well as the viral polymerase basic protein 2 (PB2). Recognizing that effective viral transmission of the influenza A virus (IAV) between humans requires efficient attachment to the upper respiratory tract and replication through the viral polymerase complex, experimental evidence demonstrates the potential H7N9 has for increased binding affinity and replication, following specific amino acid substitutions in HA and PB2. Additionally, the deletion of extended amino acid sequences in the NA stalk length was shown to produce a significant increase in pathogenicity in mice. Research shows that significant changes in transmissibility, pathogenicity and virulence are possible after one or a few amino acid substitutions. This review aims to summarise key findings from that research. To date, all strains of H7N9 viruses remain restricted to avian reservoirs, with no evidence of sustained human-to-human transmission, although mutations in specific viral proteins reveal the efficacy with which these viruses could evolve into a highly virulent and infectious, human-to-human transmitted virus.

Clonal relationships and variation in virulence among Escherichia coli strains of avian origin

1993 ◽  
Vol 14 (5) ◽  
pp. 399-409 ◽  
Author(s):  
David G. White ◽  
Maryvonne Dho-Moulin ◽  
Richard A. Wilson ◽  
Thomas S. Whittam
Keyword(s):  
Escherichia Coli ◽  
Avian Origin

Transmission of avian-origin canine influenza viruses A (H3N2) in cats

2012 ◽  
Vol 160 (3-4) ◽  
pp. 481-483 ◽  
Author(s):  
Na Lei ◽  
Zi-Guo Yuan ◽  
Shu-Fen Huang ◽  
Dun-Wei Zhang ◽  
Ai-Guo Zhang ◽  
...  
Keyword(s):  
Influenza Viruses ◽  
Avian Origin ◽  
Canine Influenza

Short communication: isolation and phylogenetic analysis of an avian-origin H3N2 canine influenza virus in dog shelter, China

Virus Genes ◽  
2013 ◽  
Vol 46 (3) ◽  
pp. 554-557 ◽  
Author(s):  
Shuo Su ◽  
Ziguo Yuan ◽  
Jidang Chen ◽  
Jiexiong Xie ◽  
Huatao Li ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
Influenza Virus ◽  
Short Communication ◽  
Canine Influenza Virus ◽  
Avian Origin ◽  
Canine Influenza
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