Post-Gastric-Bypass Hypoglycemia Successfully Treated with Alpha-Glucosidase Inhibitor Therapy

2013 ◽  
Vol 19 (3) ◽  
pp. 511-514 ◽  
Author(s):  
Shavon Frankhouser ◽  
Aakif Ahmad ◽  
Gretchen Perilli ◽  
Benjamin Quintana ◽  
Marc Vengrove
Keyword(s):  
Gastric Bypass ◽  
Inhibitor Therapy ◽  
Glucosidase Inhibitor ◽  
Alpha Glucosidase

scholarly journals Use of the Alpha-Glucosidase Inhibitor Acarbose in Patients with ‘Middleton Syndrome’: Normal Gastric Anatomy But with Accelerated Gastric Emptying Causing Postprandial Reactive Hypoglycemia and Diarrhea

2013 ◽  
Vol 27 (7) ◽  
pp. 403-404 ◽  
Author(s):  
Raymond J Playford ◽  
Charlotte Pither ◽  
Rui Gao ◽  
Stephen J Middleton
Keyword(s):  
Gastric Bypass ◽  
Gastric Emptying ◽  
Small Volume ◽  
Dietary Intervention ◽  
Partial Gastrectomy ◽  
Dietary Modification ◽  
Glucosidase Inhibitor ◽  
Reactive Hypoglycemia ◽  
Alpha Glucosidase ◽  
Symptoms And Signs

Postprandial reactive hypoglycemia, early satiety and diarrhea are well-recognized side effects following full or partial gastrectomy or gastric bypass. It has only recently been realized, however, that patients with normal gastric anatomy may experience similar symptoms and signs due to primary accelerated gastric emptying (Middleton syndrome). In previous case studies, patients responded well to the use of dietary modification (frequent small-volume meals) alone. The authors describe two patients with this syndrome who continued to experience symptoms of reactive postprandial hypoglycemia despite dietary intervention but became asymptomatic following the addition of the alpha-glucosidase inhibitor acarbose.

P1-25 THE ALPHA-GLUCOSIDASE INHIBITOR VOGLIBOSE REDUCES MYOCARDIAL INFARCT SIZE TROUGH PRODUCTION OF GLUCAGON-LIKE PEPTIDE-1 IN RABBITS

2007 ◽  
Vol 122 ◽  
pp. S68
Author(s):  
Masamitsu Iwasa ◽  
Hiroyuki Kobayashi ◽  
Shinji Yasuda ◽  
Narentuoya Bao Itta Kawamura ◽  
Takahiko Yamaki ◽  
...  
Keyword(s):  
Infarct Size ◽  
Myocardial Infarct ◽  
Myocardial Infarct Size ◽  
Glucosidase Inhibitor ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1 ◽  
Alpha Glucosidase

Produksi Dan Ekstraksi Inhibitor Alfa Glukosidase Dari Isolat Aktinomiset Jp-3

2016 ◽  
Vol 17 (2) ◽  
pp. 123
Author(s):  
Sri Pujiyanto ◽  
Rejeki Siti Ferniah ◽  
Sunarno S
Keyword(s):  
Ethyl Acetate ◽  
Active Compound ◽  
Inhibitor Activity ◽  
Glucosidase Inhibitor ◽  
Glucosidase Inhibitors ◽  
Complex Carbohydrates ◽  
Diabetes Drug ◽  
Chloroform Methanol ◽  
Alpha Glucosidase

Alpha-glucosidase inhibitors are compounds that can prevent the digestion of complex carbohydrates into glucose, so potentially used as a diabetes drug. This study aims to examine the production and extraction of alpha-glucosidase inhibitor compound from Isolate Aktinomiset JP-3 from the sea. The supernatant obtained from the culture of the JP-3 isolate was extracted using various solvents to obtain the active compound. The solvents used were chloroform, methanol, and ethyl acetate. An assay of inhibitor activity of the α-glucosidase using p-nitrophenyl α-D-glucopyranoside substrate. The activity of the enzyme is measured based on the absorbance of p-nitrophenol produced from the breaking reaction of the substrate. The results showed that extraction of alpha-glucosidase inhibitor compound with ethyl acetate yielded extract with highest inhibitor activity. Keywords: alpha-glucosidase inhibitors, actinomycetes, diabetes, extraction, fractionation

Long-term effect of alpha-glucosidase inhibitor on late dumping syndrome

1998 ◽  
Vol 13 (12) ◽  
pp. 1201-1206 ◽  
Author(s):  
TAKENAO HASEGAWA ◽  
MASASHI YONEDA ◽  
KIMIHIDE NAKAMURA ◽  
KUNIYO OHNISHI ◽  
HIROYUKI HARADA ◽  
...  
Keyword(s):  
Term Effect ◽  
Dumping Syndrome ◽  
Glucosidase Inhibitor ◽  
Long Term Effect ◽  
Late Dumping Syndrome ◽  
Alpha Glucosidase

Development of diarylpentadienone analogues as alpha-glucosidase inhibitor: Synthesis, in vitro biological and in vivo toxicity evaluations, and molecular docking analysis

2020 ◽  
Vol 104 ◽  
pp. 104277
Author(s):  
Maryam Aisyah Abdullah ◽  
Yu-Ri Lee ◽  
Siti Nurulhuda Mastuki ◽  
Sze Wei Leong ◽  
Wan Norhamidah Wan Ibrahim ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Analysis ◽  
In Vivo Toxicity ◽  
Glucosidase Inhibitor ◽  
Alpha Glucosidase ◽  
Molecular Docking Analysis

scholarly journals DPP-4 inhibitor and alpha-glucosidase inhibitor equally improve endothelial function in patients with type 2 diabetes (EDGE study)

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P1432-P1432
Author(s):  
H. Kihara ◽  
K. Nakamura ◽  
H. Oe ◽  
K. Shimada ◽  
S. Fukuda ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Endothelial Function ◽  
Glucosidase Inhibitor ◽  
Alpha Glucosidase

Miglitol, a Novel Alpha-glucosidase inhibitor, Improves Left Ventricular Function in Pacing-induced Heart Failure

2007 ◽  
Vol 13 (6) ◽  
pp. S45
Author(s):  
Hiroshi Asanuma ◽  
Masanori Asakura ◽  
Hiroyuki Takahama ◽  
Hideyuki Sasaki ◽  
Jiyoong Kim ◽  
...  
Keyword(s):  
Heart Failure ◽  
Left Ventricular Function ◽  
Ventricular Function ◽  
Left Ventricular ◽  
Glucosidase Inhibitor ◽  
Alpha Glucosidase
Sign in / Sign up

Export Citation Format

Share Document