An Integrated Analysis System for Agricultural Biotechnology Information and Web Service

2010 ◽  
Vol 2 (3) ◽  
pp. 106-110
Author(s):  
ChangKug Kim ◽  
UngHan Yoon ◽  
GangSeob Lee ◽  
DoWon Yun ◽  
HyeonSo Ji ◽  
...  
Keyword(s):  
Web Service ◽  
Agricultural Biotechnology ◽  
Integrated Analysis ◽  
Analysis System

Integrated analysis system for box truss antenna mesh performance

1986 ◽  
Author(s):  
E. BACHTELL ◽  
S. BETTADAPUR ◽  
J. COYNER
Keyword(s):  
Integrated Analysis ◽  
Analysis System

GENOMIZER: an integrated analysis system for genome-wide association data

2006 ◽  
Vol 27 (6) ◽  
pp. 583-588 ◽  
Author(s):  
Andre Franke ◽  
Andreas Wollstein ◽  
Markus Teuber ◽  
Michael Wittig ◽  
Tim Lu ◽  
...  
Keyword(s):  
Genome Wide Association ◽  
Integrated Analysis ◽  
Genome Wide ◽  
Association Data ◽  
Analysis System

scholarly journals Application of a Rapid and Integrated Analysis System (RIAS) as a High-Throughput Processing Tool for In Vitro ADME Samples by Liquid Chromatography/Tandem Mass Spectrometry

2011 ◽  
Vol 16 (3) ◽  
pp. 370-377 ◽  
Author(s):  
Andreas H. Luippold ◽  
Thomas Arnhold ◽  
Wolfgang Jörg ◽  
Beate Krüger ◽  
Roderich D. Süssmuth
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
High Throughput ◽  
Integrated Analysis ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Analysis System

Over the past decade, drug discovery programs have started to address the optimization of key ADME properties already at an early stage of the process. Hence, analytical chemists have been confronted with tremendously rising sample numbers and have had to develop methodologies accelerating quantitative liquid chromatography/tandem mass spectrometry (LC/MS/MS). This article focuses on the application of a generic and fully automated LC/MS/MS, named Rapid and Integrated Analysis System (RIAS), as a high-throughput platform for the rapid quantification of drug-like compounds in various in vitro ADME assays. Previous efforts were dedicated to the setup and feasibility study of a workflow-integrated platform combining a modified high-throughput liquid handling LC/MS/MS system controlled by a customized software interface and a customized data-processing and reporting tool. Herein the authors present an extension of this previously developed basic application to a broad set of ADME screening campaigns, covering CYP inhibition, Caco-2, and PAMPA assays. The platform is capable of switching automatically between various ADME assays, performs MS compound optimization if required, and provides a speed of 8 s from sample to sample, independently of the type of ADME assay. Quantification and peak review are adopted to the high-throughput environment and tested against a standard HPLC-ESI technology.

General Polyhedral Finite Elements for Rapid Nonlinear Analysis

2008 ◽  
Author(s):  
Mark M. Rashid ◽  
Mili Selimotic ◽  
Tarig Dinar
Keyword(s):  
Finite Element Method ◽  
Finite Element ◽  
Solid Mechanics ◽  
The Body ◽  
Integrated Analysis ◽  
Canonical Element ◽  
Cutting Geometry ◽  
Surface Representations ◽  
Analysis System ◽  
Element Method

An analysis system for solid mechanics applications is described in which a new finite element method that can accommodate general polyhedral elements is exploited. The essence of the method is direct polynomial approximation of the shape functions on the physical element, without transformation to a canonical element. The main motive is elimination of the requirement that all elements be similar to a canonical element via the usual isoparametric mapping. It is this topological restriction that largely drives the design of mesh-generation algorithms, and ultimately leads to the considerable human effort required to perform complex analyses. An integrated analysis system is described in which the flexibility of the polyhedral element method is leveraged via a robust computational geometry processor. The role of the latter is to perform rapid Boolean intersection operations between hex meshes and surface representations of the body to be analyzed. A typical procedure is to create a space-filling structured hex mesh that contains the body, and then extract a polyhedral mesh of the body by intersecting the hex mesh and the body’s surface. The result is a mesh that is directly usable in the polyhedral finite element method. Some example applications are: 1) simulation on very complex geometries; 2) rapid geometry modification and re-analysis; and 3) analysis of material-removal process steps following deformation processing. This last class of problems is particularly challenging for the conventional FE methodology, because the element boundaries are, in general, not aligned with the cutting geometry following the deformation (e.g. forging) step.

scholarly journals Integrated Machine Vision System for Evaluating Hole Expansion Ratio of Advanced High-Strength Steels

Materials ◽  
2022 ◽  
Vol 15 (2) ◽  
pp. 553
Author(s):  
Jaehoon Park ◽  
Chanhee Won ◽  
Hye-Jin Lee ◽  
Jonghun Yoon
Keyword(s):  
Computer Vision ◽  
Acoustic Emission ◽  
Expansion Ratio ◽  
Integrated Analysis ◽  
Emission Analysis ◽  
Hole Expansion ◽  
Punch Load ◽  
Hole Expansion Ratio ◽  
Load Analysis ◽  
Analysis System

In this paper, we propose a new method to estimate the hole expansion ratio (HER) using an integrated analysis system. To precisely measure the HER, three kinds of analysis methods (computer vision, punch load, and acoustic emission) were utilized to detect edge cracks during a hole expansion test. Cracks can be recognized by employing both computer vision and a punch load analysis system to determine the moment of crack initiation. However, the acoustic emission analysis system has difficulty detecting the instant of crack appearance since the magnitude of the audio signal is drowned out by noise from the press, which interrupts the differentiation of crack configuration. To enhance the accuracy for determining the HER, an integrated analysis system that combines computer vision with punch load analysis, and improves on the shortcomings of each analysis system, is newly suggested.

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