Valuing the future: recent advances and future directions in cell line development

2013 ◽  
Vol 1 (3) ◽  
pp. 243-247
Author(s):  
Mohamed Al-Rubeai ◽  
Darrin Kuystermans
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Moram A. Fagiry ◽  
Ikhlas Abdelaziz ◽  
Rob Davidson ◽  
Mustafa Z. Mahmoud

AbstractIschemic heart disease (IHD), also known as coronary artery disease (CAD), is a leading cause of morbidity and mortality in adults. The aims of this research were to study the recent advances on the prognostic and diagnostic value, drawbacks, and the future directions of cardiac magnetic resonance imaging (CMRI) in the diagnosis of IHD. One hundred patients with IHD who had been clinically diagnosed were enrolled in this study prospectively. CMRI; Siemens Magnetom Sola 1.5 T MRI scanner was used to examine the patients. To confirm the diagnosis, conventional coronary angiography was used. CMRI revealed that the left ventricular (LV) volumes and systolic function of male and female patients differed by age decile were 28.9 ± 3.5%; 32 ± 1.7%, 53.3 ± 11.2; 58 ± 6.6 ml, 100.6 ± 7.1; 98.3 ± 14.7 bpm, 5.4 ± 1.4; 5.8 ± 1.5 L/min, 189 ± 14.3; 180 ± 10.9 ml, and 136 ± 3.1; 123 ± 4.4 ml for the left ventricle ejection fraction (LVEF), stroke volume (SV), heart rate, cardiac output, end diastolic volume (EDV), and end systolic volume (ESV), respectively. CMRI has sensitivity, specificity, and accuracy of 97%, 33.33%, and 95.15%, respectively. Finally, CMRI provides a comprehensive assessment of LV function, myocardial perfusion, and viability, as well as coronary anatomy.


2015 ◽  
Vol 37 (8) ◽  
pp. 1553-1564 ◽  
Author(s):  
Huong Le ◽  
Nandita Vishwanathan ◽  
Nitya M. Jacob ◽  
Mugdha Gadgil ◽  
Wei-Shou Hu

2001 ◽  
Vol 6 (3) ◽  
pp. 172-176 ◽  
Author(s):  
Lawrence A. Pervin

David Magnusson has been the most articulate spokesperson for a holistic, systems approach to personality. This paper considers three concepts relevant to a dynamic systems approach to personality: dynamics, systems, and levels. Some of the history of a dynamic view is traced, leading to an emphasis on the need for stressing the interplay among goals. Concepts such as multidetermination, equipotentiality, and equifinality are shown to be important aspects of a systems approach. Finally, attention is drawn to the question of levels of description, analysis, and explanation in a theory of personality. The importance of the issue is emphasized in relation to recent advances in our understanding of biological processes. Integrating such advances into a theory of personality while avoiding the danger of reductionism is a challenge for the future.


2020 ◽  
pp. 60-69
Author(s):  
Z. A.-G. Radzhabova ◽  
M. Д. Kotov ◽  
A. S. Mitrofanov ◽  
Z. S. Bekyasheva ◽  
E. V. Levchenko

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