Candidate molecules for chemical chaperone therapy of GM1-gangliosidosis

2013 ◽  
Vol 5 (13) ◽  
pp. 1551-1558 ◽  
Author(s):  
Katsumi Higaki ◽  
Haruaki Ninomiya ◽  
Yoshiyuki Suzuki ◽  
Eiji Nanba
Keyword(s):  
Gm1 Gangliosidosis ◽  
Chemical Chaperone ◽  
Chemical Chaperone Therapy

MLO03 Chemical chaperone therapy: clinical effect in murine GM1-gangliosidosis

2007 ◽  
Vol 11 ◽  
pp. 31
Author(s):  
Y. Suzuki ◽  
S. Ichinomiya ◽  
M. Kurosawa ◽  
M. Ohkubo ◽  
J. Matsuda ◽  
...  
Keyword(s):  
Clinical Effect ◽  
Gm1 Gangliosidosis ◽  
Chemical Chaperone ◽  
Chemical Chaperone Therapy

scholarly journals Chemical chaperone therapy for brain pathology in GM1-gangliosidosis

2003 ◽  
Vol 100 (26) ◽  
pp. 15912-15917 ◽  
Author(s):  
J. Matsuda ◽  
O. Suzuki ◽  
A. Oshima ◽  
Y. Yamamoto ◽  
A. Noguchi ◽  
...  
Keyword(s):  
Brain Pathology ◽  
Gm1 Gangliosidosis ◽  
Chemical Chaperone ◽  
Chemical Chaperone Therapy

Chemical chaperone therapy: clinical effect in murine GM1-gangliosidosis

2007 ◽  
Vol 62 (6) ◽  
pp. 671-675 ◽  
Author(s):  
Yoshiyuki Suzuki ◽  
Satoshi Ichinomiya ◽  
Mieko Kurosawa ◽  
Masato Ohkubo ◽  
Hiroshi Watanabe ◽  
...  
Keyword(s):  
Clinical Effect ◽  
Gm1 Gangliosidosis ◽  
Chemical Chaperone ◽  
Chemical Chaperone Therapy

Potent chemical chaperone compounds for GM1-gangliosidosis: N-substituted (+)-conduramine F-4 derivatives

MedChemComm ◽  
2015 ◽  
Vol 6 (2) ◽  
pp. 306-310 ◽  
Author(s):  
Shinichi Kuno ◽  
Katsumi Higaki ◽  
Atsushi Takahashi ◽  
Eiji Nanba ◽  
Seiichiro Ogawa
Keyword(s):  
Inhibitory Activity ◽  
Gm1 Gangliosidosis ◽  
Chemical Chaperone ◽  
Chemical Chaperones ◽  
Enzyme Enhancement

The development of chemical chaperones to decrease the inhibitory activity while increasing the enzyme enhancement activity is described.

Lysosomal accumulation of Trk protein in brain of GM1-gangliosidosis mouse and its restoration by chemical chaperone

2011 ◽  
Vol 118 (3) ◽  
pp. 399-406 ◽  
Author(s):  
Ayumi Takamura ◽  
Katsumi Higaki ◽  
Haruaki Ninomiya ◽  
Tomoko Takai ◽  
Junichiro Matsuda ◽  
...  
Keyword(s):  
Gm1 Gangliosidosis ◽  
Chemical Chaperone ◽  
Lysosomal Accumulation

scholarly journals Chemical chaperone therapy, a new strategy for genetic skin fragility disorders

2016 ◽  
Vol 25 (3) ◽  
pp. 183-184 ◽  
Author(s):  
Jean Christopher Chamcheu ◽  
Imtiaz A. Siddiqui ◽  
Hasan Mukhtar
Keyword(s):  
Chemical Chaperone ◽  
New Strategy ◽  
Skin Fragility ◽  
Chemical Chaperone Therapy
Sign in / Sign up

Export Citation Format

Share Document