scholarly journals Human papillomavirus and Epstein-Barr virus in nasopharyngeal carcinoma in a non-endemic eastern european population

Neoplasma ◽  
2016 ◽  
Vol 63 (01) ◽  
pp. 107-114 ◽  
Author(s):  
M. SVAJDLER ◽  
J. KASPIRKOVA ◽  
R. MEZENCEV ◽  
J. LACO ◽  
T. TORDAY ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
European Population ◽  
Eastern European ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Epstein‐Barr virus and human papillomavirus serum antibodies define the viral status of nasopharyngeal carcinoma in a low endemic country

2020 ◽  
Vol 147 (2) ◽  
pp. 461-471 ◽  
Author(s):  
Julia Simon ◽  
Lea Schroeder ◽  
Kate Ingarfield ◽  
Stefan Diehl ◽  
Jill Werner ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Endemic Country ◽  
Serum Antibodies ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Epstein-Barr Virus, Human Papillomavirus, and Flow Cytometric Cell Cycle Kinetics in Nasopharyngeal Carcinoma and Inverted Papilloma among Egyptian Patients

1998 ◽  
Vol 14 (2) ◽  
pp. 113-120 ◽  
Author(s):  
S. K. Kassim ◽  
S. A. Ibrahim ◽  
S. Eissa ◽  
S. S. A. Zaki ◽  
M. A. El-Begermy ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Human Papillomavirus ◽  
Nasopharyngeal Carcinoma ◽  
Tumor Recurrence ◽  
Epstein Barr Virus ◽  
Inverted Papilloma ◽  
Hpv 16 ◽  
Primary Tumors ◽  
Barr Virus ◽  
Epstein Barr

It is widely accepted that the Epstein-Barr virus is etiologically associated with the development of nasopharyngeal carcinoma. The human papillomavirus is also associated with inverted papilloma. We used the polymerase chain reaction technique to detect both viruses in both types of tumors. Flow cytometry was also used to study the DNA pattern and proliferative behavior of the tumors in relation to the viruses. EBV was detected in 13/20 (65%) of NPC specimens, and in none of IP (n= 10) or control specimens (n= 10). This indicates the contribution of EBV as an etiologic factor in NPC. Five cases of NPC (25%) were positive for HPV 16, two of them were EBV positive. Four HPV 16 positive cases were found among cases with inverted papilloma, but none among the control cases. Flow cytometry revealed that all NPC, IP, and control samples were diploid except one aneuploid NPC sample. Proliferative capacity (PC) of primary tumors was predictive of tumor recurrence in NPC. Using 13.6% as a cut-off point for PC, we were able to discriminate between high risk and low risk groups with 100% sensitivity and 86% specificity. PC can be used as a baseline prognostic parameter in NPC, making it possible to modify courses of treatment in an attempt to inhibit tumor recurrence.

Combined Epstein-Barr Virus and Human Papillomavirus Infection in Nasopharyngeal Carcinoma

1995 ◽  
Vol 113 (2) ◽  
pp. P76-P76
Author(s):  
Christopher H. Rassekh ◽  
Peter Rady ◽  
Stephen Tyring ◽  
Istvan Arany ◽  
Sharen Knudsen ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection ◽  
Epstein Barr

scholarly journals Human papillomavirus and Epstein-Barr virus in nasopharyngeal carcinoma in a low-incidence population

Head & Neck ◽  
2013 ◽  
Vol 36 (4) ◽  
pp. 511-516 ◽  
Author(s):  
Snjezana Dogan ◽  
Matthew L. Hedberg ◽  
Robert L. Ferris ◽  
Tanya J. Rath ◽  
Adel M. Assaad ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr ◽  
Low Incidence

Combined Epstein-Barr Virus and Human Papillomavirus Infection in Nasopharyngeal Carcinoma

1998 ◽  
Vol 108 (3) ◽  
pp. 362-367 ◽  
Author(s):  
Christopher H. Rassekh ◽  
Peter L. Rady ◽  
Istvan Arany ◽  
Stephen K. Tyring ◽  
Sharen Knudsen ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection ◽  
Epstein Barr

Studies of Epstein-Barr Virus Antigens Using Immunoperoxidase and Immunofluorescence Techniques

1975 ◽  
Vol 33 ◽  
pp. 342-343
Author(s):  
R. Stephens ◽  
K. Traul ◽  
D. Woolf ◽  
P. Gaudreau
Keyword(s):  
Electron Microscopy ◽  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
If Technique ◽  
Infected Cells ◽  
Virus Antigens ◽  
Epstein Barr ◽  
Virus Capsid Antigen ◽  
Antigen Reactivity

A number of antigens have been found associated with persistent EBV infections of lymphoblastoid cells. Identification and localization of these antigens were principally by immunofluorescence (IF) techniques using sera from patients with nasopharyngeal carcinoma (NPC), Burkitt lymphoma (BL), and infectious mononucleosis (IM). Our study was mainly with three of the EBV related antigens, a) virus capsid antigen (VCA), b) membrane antigen (MA), and c) early antigens (EA) using immunoperoxidase (IP) techniques with electron microscopy (EM) to elucidate the sites of reactivity with EBV and EBV infected cells.Prior to labeling with horseradish peroxidase (HRP), sera from NPC, IM, and BL cases were characterized for various reactivities by the indirect IF technique. Modifications of the direct IP procedure described by Shabo and the indirect IP procedure of Leduc were made to enhance penetration of the cells and preservation of antigen reactivity.

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