Differentiation of the effects of somatotropin and enhanced growth rate on the occurrence of osteochondrosis in pigs
One hundred and twenty Yorkshire pigs, equal numbers of gilts and barrows, with an initial average weight of 69 kg were used in the present experiment. The animals were treated with 2 mg d−1 of recombinant porcine somatotropin (rpST) either by daily injection or by slow-release implant, while the control animals were treated with a sham implant. The daily injection of rpST increased daily weight gain (P < 0.0001) and decreased feed/gain ratio (P < 0.0001) and daily feed intake (P < 0.0001). Barrows grew faster (P = 0.02) and ate more feed (P = 0.0001) than gilts. On reaching ~ 100 kg, all pigs were slaughtered, and 60 pigs (two from each pen) were randomly selected for carcass evaluation. Carcass lean content was increased (P < 0.0001) and carcass fat content was decreased (P < 0.0001) in animals treated with rpST by daily injection. Animals treated with rpST by the slow-release implant were not different from the control animals in terms of growth performance and carcass characteristics. No overt lameness was observed in any of the pigs in the experiment. However, rpST treatment, regardless of the method of administration, increased the incidence and severity of osteochondrosis and reduced glycosaminoglycan concentration in the cartilage of the weight-bearing area of humeral and femoral condyles. These changes were independent of enhanced growth rate and carcass lean content. The results indicated that somatotropin treatment predisposes pigs to osteochondrosis. Key words: Osteochondrosis, growth rate, growth hormone, joint cartilage, pigs