The use of in vivo magnetic resonance imaging and spectroscopy to study porcine stress syndrome in young, halothane-susceptible pigs: Preliminary results

1994 ◽  
Vol 74 (1) ◽  
pp. 37-43
Author(s):  
Edward G. Janzen ◽  
Wendy A. Stewart ◽  
Rheal A. Towner ◽  
Paula J. Gareau
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Free Water ◽  
Simultaneous Increase ◽  
Resonance Spectroscopy ◽  
Resonance Imaging ◽  
Stress Syndrome ◽  
Porcine Stress Syndrome

Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) studies on young, halothane-susceptible pigs (4 wk old) are reported. The proton image shows distinct changes in shape of the hindleg muscle as the stress syndrome develops. Simultaneous evaluations of the "free water" content by volume selective spectroscopy shows an increase of about 40% after onset of the syndrome. The in vivo phosphorus spectrum obtained as a function of time before and after the stress event clearly shows a drop in phosphocreatine with simultaneous increase in inorganic phosphate. A drop in pH can also be detected after some delay. This study illustrates the broad applicability of noninvasive MRI and MRS in investigations of porcine stress syndrome. Key words: PSS, porcine stress syndrome, MRI, magnetic resonance imaging, 31P MRS, phosphorus-31 magnetic resonance spectroscopy

scholarly journals In Vivo Phenotyping of the ob/ob Mouse by Magnetic Resonance Imaging and 1H-Magnetic Resonance Spectroscopy*

Obesity ◽  
2006 ◽  
Vol 14 (3) ◽  
pp. 405-414 ◽  
Author(s):  
Laura Calderan ◽  
Pasquina Marzola ◽  
Elena Nicolato ◽  
Paolo F. Fabene ◽  
Chiara Milanese ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Resonance Spectroscopy ◽  
Resonance Imaging ◽  
1H Magnetic Resonance Spectroscopy

Neuroimaging for the Clinician

2017 ◽  
Author(s):  
Joshua P Klein
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Active Role ◽  
Cellular Level ◽  
Vascular Pathology ◽  
Resonance Spectroscopy ◽  
Resonance Imaging ◽  
Spinal Imaging

Modern neuroimaging has revolutionized the practice of neurology by allowing visualization and monitoring of evolving pathophysiologic processes. High-resolution magnetic resonance imaging (MRI) can now resolve structural abnormalities on a near-cellular level. Advances in functional imaging can assess the in vivo metabolic, vascular, and functional states of neuronal and glial populations in real time. Given the high density of data obtained from neuroimaging studies, it is essential for the clinician to take an active role in understanding the nature and significance of imaging abnormalities. This chapter reviews computed tomography and MRI techniques (including angiography and advanced sequences), specialized protocols for investigating specific diagnoses, risks associated with imaging, disease-specific imaging findings with general strategies for interpretation, and incidental findings and artifacts. Figures include computed tomography, T1- and T2-weighted signal intensity, diffusion-weighted magnetic resonance imaging, magnetic resonance spectroscopy, imaging in epilepsy and dementia, extra-axial versus intra-axial lesions, typical lesions of multiple sclerosis, spinal imaging, spinal pathology, vascular pathology, intracranial hemorrhage, and common imaging artifacts. Tables list Hounsfield units, patterns of enhancement from imaging, advanced techniques in imaging, magnetic resonance imaging sequences, and the evolution of cerebral infarction and intraparenchymal hemorrhage on magnetic resonance imaging. This review contains 12 figures, 6 tables, and 213 references.

Comparison of Diagnostic Accuracy of Magnetic Resonance Spectroscopy with Conventional Magnetic Resonance Imaging for Brain Tumors and Correlation with Histopathology as Gold Standard

2021 ◽  
Vol 15 (9) ◽  
pp. 4009-4011
Author(s):  
Saulat Sarfraz ◽  
Mahwish Farzana
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Brain Tumors ◽  
Diagnostic Accuracy ◽  
Gold Standard ◽  
Age Groups ◽  
Resonance Spectroscopy ◽  
Resonance Imaging ◽  
Conventional Mri

Background: In spite of recent advances in the use of diagnostic imaging modalities none of them has a hundred percent accuracy. So, misdiagnosis still occurs. Many trials are being done to evaluate the accuracy of these tools individually or in combination. The most useful investigation is MRI which broadly gives information of lesion as well its relationship with surrounding structures. While magnetic resonance spectroscopy further characterizes the lesion into benign or malignant. So this study is bit superior giving more details. By enlarge histopathology is gold standard for ultimate diagnosis. However these radiological investigations are extremely important for preoperative planning as well management of the lesion. In this study we compare the diagnostic accuracy of Magnetic Resonance Spectroscopy (MRS) with conventional MRI (Magnetic Resonance Imaging) sequences for diagnosis of brain tumors keeping histopathology as gold standard. Methods: The study was performed in 150 clinically suspected cases which were referred to Radiology Department from OPD, Indoor, Emergency and private sources from outside the hospital. Results: Majority 85(56.7%) were adult males and 65(43.3%) were adult females. The study was divided into two major age groups. There were 33cases (22%) with average age 20-35 years. The other age group 36-50 years had 40(26.7%) Majority of the cases 77(51.3%) were of average >50 years of age. The higher age groups showed a female dominance. Histopathology of 100(66.7%) cases confirmed positive and 50(33.3%) negative for MR Spectroscopy. On comparison of conventional MRI with contrast, and Histopathology it was observed that the sensitivity of MRI was 74.0% and the specificity 82.0%.The positive and negative predictive values gave a lower accuracy rate of 76.6%. Conclusion: The conclusion of our study is that MRS is a rigorous, non-invasive, safe and convenient imaging modality for the evaluation of brain tumors as compared to MRI. Keywords: Brain tumors, MRI, MRS, Histopathology

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