scholarly journals In Vivo Phenotyping of the ob/ob Mouse by Magnetic Resonance Imaging and 1H-Magnetic Resonance Spectroscopy*

Obesity ◽  
2006 ◽  
Vol 14 (3) ◽  
pp. 405-414 ◽  
Author(s):  
Laura Calderan ◽  
Pasquina Marzola ◽  
Elena Nicolato ◽  
Paolo F. Fabene ◽  
Chiara Milanese ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Resonance Spectroscopy ◽  
Resonance Imaging ◽  
1H Magnetic Resonance Spectroscopy

The use of in vivo magnetic resonance imaging and spectroscopy to study porcine stress syndrome in young, halothane-susceptible pigs: Preliminary results

1994 ◽  
Vol 74 (1) ◽  
pp. 37-43
Author(s):  
Edward G. Janzen ◽  
Wendy A. Stewart ◽  
Rheal A. Towner ◽  
Paula J. Gareau
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Free Water ◽  
Simultaneous Increase ◽  
Resonance Spectroscopy ◽  
Resonance Imaging ◽  
Stress Syndrome ◽  
Porcine Stress Syndrome

Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) studies on young, halothane-susceptible pigs (4 wk old) are reported. The proton image shows distinct changes in shape of the hindleg muscle as the stress syndrome develops. Simultaneous evaluations of the "free water" content by volume selective spectroscopy shows an increase of about 40% after onset of the syndrome. The in vivo phosphorus spectrum obtained as a function of time before and after the stress event clearly shows a drop in phosphocreatine with simultaneous increase in inorganic phosphate. A drop in pH can also be detected after some delay. This study illustrates the broad applicability of noninvasive MRI and MRS in investigations of porcine stress syndrome. Key words: PSS, porcine stress syndrome, MRI, magnetic resonance imaging, 31P MRS, phosphorus-31 magnetic resonance spectroscopy

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