Effects of intramuscular injections of folic acid on folates status and growth performance of weanling pigs

1991 ◽  
Vol 71 (4) ◽  
pp. 1223-1231 ◽  
Author(s):  
Marie Letendre ◽  
Jean F. Bernier ◽  
Christiane L. Girard ◽  
J. Jacques Matte

In the first of two trials, 24 piglets (2 wk old) were used to measure the dose–response curve of serum folates after intramuscular injections of folic acid (0, 10, 20 or 30 mg). Administration of 10 mg of folic acid was sufficient (P < 0.01) to prevent the decrease of serum folates observed 1 wk after weaning. In the second trial, 72 piglets (2 wk old) were used to study the effect of repeated intramuscular injections of folic acid (0 or 2.5 mg kg−1 of body weight) on hematological status, liver development, and concentrations of serum and hepatic folates, as well as on growth performance up to 10 wk of age. Serum and liver folates were increased (P < 0.01) by repeated injections of folic acid. However, no treatment effects (P > 0.10) were observed on total content of DNA, RNA and protein in the liver. Hemoglobin, hematocrit, total body weight gain, gain: feed ratio and total feed intake were also not influenced (P > 0.10) by the injections of folic acid. Therefore, although a decrease in serum folates is observed during the weaning period, it does not seem to have detrimental effects on the growth performance of weanling piglets. Key words: Folic acid, folates, growth performance, piglets, weaning

Development ◽  
1977 ◽  
Vol 41 (1) ◽  
pp. 289-294
Author(s):  
R. R. Schmidt ◽  
K. P. Chepenik ◽  
B. V. Paynton

Pregnant rats were subjected to either a folic-acid-deficient regimen that produces multiple congenital skeletal malformations, or a control folic-acid-supplemented regimen. Fetal limbs were extirpated on days 16 and 18 of gestation, pooled from each litter, homogenized, and aliquots set aside for hydroxyproline, protein and DNA determinations. We found that (1) the amount of protein recovered per treated limb was approximately half that of controls on both days, (2) the amount of protein recovered per treated or controlday-18 limb was twice that of a day-16 limb, (3) treated limbs constituted the same percentage of total body weight as in controls on day 16, but a smaller percentage than in controls on day 18, and (4) the concentration of hydroxyproline (μg/mg protein) was significantly less for treated limbs than for controls on day 18 of gestation. We noted also that: (1) lowest hydroxyproline concentrations were found in limbs from treated fetuses with gross limb malformations, (2) intermediate concentrations were found in limbs of treated fetuses not exhibiting gross limb malformations, and (3) highest concentrations were found in control limbs. We suggest that the treatment resulted in (1) a decreased rate of accumulation of protein in limbs prior to day 16, but not from day 16 to day 18, (2) a decreased rate of accumulation of some non-protein component(s) in treated limbs from day 16 to day 18, and (3) an altered collagen metabolism.


2013 ◽  
Vol 93 (2) ◽  
pp. 243-249 ◽  
Author(s):  
H. Lu ◽  
S.A. Adedokun ◽  
A. Preynat ◽  
V. Legrand-Defretin ◽  
P. A. Geraert ◽  
...  

Lu, H., Adedokun, S. A., Preynat, A., Legrand-Defretin, V., Geraert, P. A., Adeola, O. and Ajuwon, K. M. 2013. Impact of exogenous carbohydrases and phytase on growth performance and nutrient digestibility in broilers. Can. J. Anim. Sci. 93: 243–249. The effect of supplementing corn–soybean-based diets with Rovabio®Max AP, an exogenous enzyme mix with carbohydrase (xylanase and β-glucanase) and phytase activities to broiler chickens was evaluated. Male Ross 708 broilers were assigned to four diets: positive control (PC), negative control (NC), deficient in metabolizable energy (ME), crude protein (CP), calcium (Ca) and non-phytate phosphorus (nPP), relative to the PC, by 100 kcal kg−1, 5 g kg−1, 1.1 g kg−1and 1.6 g kg−1, respectively, in the starter and grower diets; and NC+Rovabio®at 0.05 or 0.075 g kg−1diet. Starter diets were fed from day 0 to day 21 and grower diets from day 22 to day 42. Body weight (BW) and body weight gain on days 22 and 42 were increased (P<0.05) by enzyme supplementation. Enzyme addition increased (P<0.05) feed intake from day 22 to day 42 and overall (day 0 to day 42). Gain to feed ratio (G:F) was significantly increased (P<0.05) with enzyme supplementation during both starter and grower phases. Enzyme addition increased (P<0.05) serum phosphorus (P) concentration on day 21. On day 42 enzyme supplementation increased (P<0.05) the apparent ileal digestibility of P, dry matter (DM), energy, and N. Addition of a combination of carbohydrases (xylanase and β-glucanase) and phytase to corn–soybean-based diets deficient in ME, CP, Ca and P resulted in a significant increase in growth performance and utilization of P, DM, energy and N in broiler chickens.


Author(s):  
G. Rajkumar ◽  
M. T. Dipu ◽  
K. Lalu ◽  
K. Shyama ◽  
P. S. Banakar

An experiment was conducted to evaluate the effect of maize green fodder produced by hydroponics system on the performance of eighteen weaned crossbred calves and Calves were divided into three groups T1, T2 and T3 of six each as uniformly. The calf starter in dietary treatments T1, T2 and T3 contained 24, 20 and 17 per cent of Crude Protein (CP), respectively and 70 per cent Total Digestible Nutrients (TDN). The T2 and T3 treatments were made iso-nitrogenous with T1 by supplementing hydroponics maize fodder. The results obtained in the present study showed significant difference among different treatment groups regarding Dry matter intake (DM), total body weight gain, Average daily gain (ADG) and Feed conversion ratio (FCR) with a higher (P less than 0.05) values observed for calves belonging to T3 than groups T1 and T2. Data on digestibility of nutrients does not reveal any difference (P>0.05) among treatment groups. Cost per kg gain was significantly (P less than 0.05) lower in T3 (Rs.102.14) than groups T2 (Rs. 111.64) and T1 (Rs. 119.82). On conclusion, feeding of hydroponics maize fodder as a partial feed substitute of calf starter on protein basis at seven per cent level improves the DM intake, total body weight gain, ADG and lowers the cost per kg body weight gain.


1970 ◽  
Vol 38 (1-2) ◽  
pp. 102-107 ◽  
Author(s):  
AKM Masum ◽  
MN Islam ◽  
MAS Khan

An experiment was conducted to study the utilization of soymilk as milk replacer for raising calves. Nine crossbred calves were selected and divided into three groups on the basis of their body weight and genotype. The calves of group A were reared by cow milk, group B reared by strained soymilk and group C reared by unstrained soymilk. It was found that, total body weight gain of group A, B and C were 13.933 ± 1.222, 13.800 ± 0.917 and 13.233 ± 1.537 Kg, respectively. There was no significant difference among the three groups of calves. Non-significant differences were also seen for increment in wither height (5.588 ± 0.508, 5.419 ± 0.529 and 5.080 ± 0.440 cm, respectively), length (6.096 ± 0.440, 5.927 ± 0.388 and 5.503 ± 0.388 cm, respectively) and heart-girth (5.842 ± 0.440, 5.588 ± 0.916 and 5.419 ± 0.388 cm, respectively) of calves. Economic analysis showed that soymilk was cheaper than cow milk (Tk. 8.0 vs Tk. 44.0). It can be concluded that soymilk as milk replacer could be used successfully for raising dairy calves. DOI: http://dx.doi.org/10.3329/bjas.v38i1-2.9918 BJAS 2009; 38(1-2): 102-107


2018 ◽  
Vol 53 (1) ◽  
pp. 121-124
Author(s):  
Camilla Alves Santos ◽  
Flavio Farias ◽  
Ana Karina Teixeira ◽  
João Luís Rocha ◽  
Ana Carolina Guerrelhas ◽  
...  

Abstract: The objective of this work was to assess polymorphisms within Litopenaeus vannamei candidate genes related to growth performance, and a possible association between weight genotypes and phenotypes in two shrimp closed lines. Three EST-SSR (serine-arginine, 60S ribosomal, and troponin) and one EST-SNP (crustacyanin) were selected and evaluated in L. vannamei and seven other marine shrimp species, besides two freshwater species. Genotypes had no effect on total body weight. Although no association was observed in the sampled population, these markers showed amplification for most of the evaluated species and, therefore, may be useful in further genetic studies on shrimp species.


Author(s):  
Ismael Othman Karim

The present study is carried out to study the effect of Folic Acid (FA) by injection and supplementary on animal body weight gain, Testes volume before slaughtering, Testes volume after slaughtering, Testosterone concentration in blood, and FA concentration in blood. Twenty-five (25) Karadi male lambs five months aged and the average weight was 24.54 ±1.92 kg were used in this experiment. The animals weighed after three months of treatment to get animal increased live weight, The testes measured after one, two, and three months of treatment to calculate testes volume, testosterone, and FA concentration level in the blood were taken after one, two, and three months of treatment. The present study demonstrated that animal body weight, animal body weight gain, and total body weight gain significantly not increased (p>0.05). Testicular length, and testicular circumference not increased (p>0.05) after 1st, 2nd, and 3rd months after treatment, and after slaughtering. However, testicular high increased (p<0.05) after each month of treatment and slaughtering. Testosterone concentration in the blood significantly not different (p>0.05) reported between treatments after the 1st, 2nd, and 3rd months of treatment. FA concentration in the blood significantly increased (p<0.05) when used 3 and 6 mg FA by injection compared to control after 1st and 2nd months of treatment. However, blood FA concentration increased (p<0.05) when used FA 6mg/ml as an injection after the 2nd month of treatment compared to control. While using FA by supplementation and injection significantly (p>0.05) on the diameter and circumference of seminiferous tubules, germ cells thickness, and lumen diameters.


1983 ◽  
Vol 54 (3) ◽  
pp. 192-199
Author(s):  
Shigeki KOBAYASHI ◽  
Yutaka YOSHIDA ◽  
Sakae KAWASHIMA

2019 ◽  
Vol 20 (1) ◽  
pp. 62-66
Author(s):  
Magdy Amer

This study was performed on to evaluate the effect of some probiotic strains (Pediococcus acidophilus and Pedicoccus pentosaceus) on performance, blood picture and some biochemical parameters in serum of treated calves (10 weaned calves 90-115 kg). Calves were classified into 2 equal groups (each of 5 calves). The 1st group was served as the control group while the second group was given Maxboost® (20gm/head/day) in drinking water (after fermentation for 2-3 hours) for five months. Calves were weighed monthly to calculate the body weight gain till the end of the experiment whole blood weight and serum were collected from both groups at 1st, 2nd, 3rd, 4th and 5th month. Results revealed a significant increase in total body weight, body gain, total erythrocytes count, hemoglobin content, total leucocytes count, total protein and mean corpuscular hemoglobin. On the other hand, there were a significant decrease in serum aspartate transaminase (AST), serum alanine transaminase (ALT) and urea in pediococcus treated group compared to the control one.


2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Moreno Zanardo ◽  
Fabio Martino Doniselli ◽  
Anastassia Esseridou ◽  
Massimiliano Agrò ◽  
Nicol Antonina Rita Panarisi ◽  
...  

Abstract Objectives Iodinated contrast media (ICM) could be more appropriately dosed on patient lean body weight (LBW) than on total body weight (TBW). Methods After Ethics Committee approval, trial registration NCT03384979, patients aged ≥ 18 years scheduled for multiphasic abdominal CT were randomised for ICM dose to LBW group (0.63 gI/kg of LBW) or TBW group (0.44 gI/kg of TBW). Abdominal 64-row CT was performed using 120 kVp, 100–200 mAs, rotation time 0.5 s, pitch 1, Iopamidol (370 mgI/mL), and flow rate 3 mL/s. Levene, Mann–Whitney U, and χ2 tests were used. The primary endpoint was liver contrast enhancement (LCE). Results Of 335 enrolled patients, 17 were screening failures; 44 dropped out after randomisation; 274 patients were analysed (133 LBW group, 141 TBW group). The median age of LBW group (66 years) was slightly lower than that of TBW group (70 years). Although the median ICM-injected volume was comparable between groups, its variability was larger in the former (interquartile range 27 mL versus 21 mL, p = 0.01). The same was for unenhanced liver density (IQR 10 versus 7 HU) (p = 0.02). Median LCE was 40 (35–46) HU in the LBW group and 40 (35–44) HU in the TBW group, without significant difference for median (p = 0.41) and variability (p = 0.23). Suboptimal LCE (< 40 HU) was found in 64/133 (48%) patients in the LBW group and 69/141 (49%) in the TBW group, but no examination needed repeating. Conclusions The calculation of the ICM volume to be administered for abdominal CT based on the LBW does not imply a more consistent LCE.


Author(s):  
Vijayalingam Thavasi Alagan ◽  
Rajesh Nakulan Vatsala ◽  
Ilavarasan Sagadevan ◽  
Vairamuthu Subbiah ◽  
Venkataramanan Ragothaman

Abstract Background An effort was made to assess the effectiveness of dietary supplementation of Ulva lactuca (U. lactuca), a seaweed and Azolla individually and in combination on different physiological parameters of Aseel chicken. A total of 40 Aseel chicks of 8 weeks old were allocated into four groups, C1 (control), T1 (Azolla alone), T2 (seaweed alone) and T3 (seaweed plus Azolla). Aseel chicks in C1 were fed with formulated grower feed alone, birds in T1 had control diet with 5% Azolla, birds in T2 had control diet with 3% U. lactuca and birds in T3 had control diet admixtured with 5% of Azolla and 3% of U. lactuca. Parameters were recorded for a continuous period of 2 months in 15 days interval. Results The growth performance was found to be significant (P ≤ 0.05) during 30 days of feed trials and highly significant (P ≤ 0.01) during 45 and 60 days of treatment. Birds in T3 had a higher body weight gain, shank length and feed conversion efficiency followed with T1 and T2 compared to C1. PCV, RBC, WBC and heterophil counts were not influenced (P ≥ 0.05) by dietary treatments. Uric acid, creatinine, AST, glucose, triglycerides and magnesium levels revealed a high significant (P ≤ 0.01) variation, and cholesterol level showed significant (P ≤ 0.05) changes during 30th and 60th day of feed trials between the control and treatment groups. Total protein, globulin, phosphorus and electrolytes like Na, K and Cl levels were not significant (P ≥ 0.05) during 30th day and were highly significant (P ≤ 0.01) during the 60th day of the trial. Conclusions It could be noted that inclusion of U. lactuca and Azolla as feed supplement in grower chicken had a better body weight gain when given in combination (U. lactuca and Azolla) rather than supplemented with the sole entity. Based on the haematological and serum biochemical analysis, the supplementation of U. lactuca and Azolla at the levels included in this trial did not pose any threat to the physiological well-being of Aseel chicken.


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