BIOAVAILABILITY OF COPPER IN PIG FECES

1986 ◽  
Vol 66 (4) ◽  
pp. 1145-1148 ◽  
Author(s):  
O. A. IZQUIERDO ◽  
D. H. BAKER
Keyword(s):  
Key Words ◽  
Copper Concentration ◽  
Chick Growth ◽  
Liver Copper ◽  
Young Pigs ◽  
Growth Assay ◽  
Copper Bioavailability ◽  
Effect On Growth

A chick growth assay was conducted to determine the bioavailability of copper in pig feces. Feces were collected from young pigs fed a 650 mg Cu kg−1 diet. After drying, they were fed to chicks to provide graded intakes of copper. Graded levels of CuSO4∙5H2O were also fed, and the increase in liver copper concentration was compared between the two sources. Dietary addition of 500 mg Cu kg−1 diet as CuSO4∙5H2O depressed chick growth and increased liver copper concentration 42-fold. Addition of 748 mg Cu kg−1 diet as dried pig feces had no effect on growth and increased liver Cu concentration only threefold. These data suggest that the Cu in pig feces is poorly available. Relative to oral CuSO4 providing 250 mg Cu kg−1 diet, orally ingested fecal Cu exhibits a bioavailability no greater than 35.6%. Key words: Swine, chickens, inorganic copper, fecal copper, copper bioavailability

Protein quality and metabolizable energy yield of pork loin are not affected by cooking

1995 ◽  
Vol 75 (3) ◽  
pp. 493-495
Author(s):  
Jason L. Emmert ◽  
Audra E. Hortin ◽  
Yanming Han ◽  
David H. Baker
Keyword(s):  
Key Words ◽  
Protein Quality ◽  
Metabolizable Energy ◽  
Energy Yield ◽  
Chick Growth ◽  
Growth Assay ◽  
Pork Loin

In a chick growth assay, the protein quality (PER) of pork loin was not affected by roasting, but both raw and roasted pork loin produced higher PER values than that obtained with dehulled SBM. True metabolizable energy, assessed in a precision-fed cockerel assay, was similar for raw and roasted pork loin. Key words: Protein quality, energy yield, pork loin, cooking, chicks

Conception rate in hill ewes given a multi-trace element/vitamin bolus before mating

1998 ◽  
Vol 1998 ◽  
pp. 216-216
Author(s):  
R.G. Hemingway ◽  
J.J. Parkins ◽  
N.S. Ritchie
Keyword(s):  
Vitamin D ◽  
Trace Element ◽  
Copper Concentration ◽  
Conception Rate ◽  
Single Element ◽  
Glutathione Peroxidase Activity ◽  
Liver Copper ◽  
Foetal Mortality ◽  
Veterinary Surgeon ◽  
Total Life

Conception rate in ewes, mainly by reduction in early foetal mortality, have been improved by a range of individual supplementary trace elements (especially Se, but also Cu, Co, Mn and Zn) given prior to mating (Hidiroglou, 1979). Ritchie et al. (1997) has described significant improvements in liver copper concentration and blood glutathione peroxidase activity (GSHPx) in ewes given a single sustained-release multi-trace element and vitamin bolus which incorporates a grinder (‘Small-Trace’, Agrimin Ltd., Brigg DN20 0SP). This communication describes studies in the conception rate of ewes given this bolus at three grazing sites. Each flock was judged by the veterinary surgeon concerned to require routine trace element supplementation and which had previously been given by various combinations of injections, drenches, single element boluses and/or copper oxide needles.Each bolus contained 5.3g Cu, 50mg Se, 90mg Co, lOOmg I, 4.7g Zn and 3.3g Mn with (iu) 268 x 103 vitamin A, 54 x 103 vitamin D and 800 vitamin E. About one-half of each nutrient is released in the first 6-8 weeks; thereafter the rate slows and the total life of the bolus is c. 7 months. (Ritchie et al. 1997).

scholarly journals Association between Liver Copper Concentration and Subclinical Hepatitis in Doberman Pinschers

2004 ◽  
Vol 18 (5) ◽  
pp. 647-650 ◽  
Author(s):  
P.J.J. Mandigers ◽  
T.S.G.A.M. Ingh ◽  
P. Bode ◽  
E. Teske ◽  
J. Rothuizen
Keyword(s):  
Copper Concentration ◽  
Liver Copper ◽  
Doberman Pinschers

Conception rate in hill ewes given a multi-trace element/vitamin bolus before mating

1998 ◽  
Vol 1998 ◽  
pp. 216-216
Author(s):  
R.G. Hemingway ◽  
J.J. Parkins ◽  
N.S. Ritchie
Keyword(s):  
Vitamin D ◽  
Trace Element ◽  
Copper Concentration ◽  
Conception Rate ◽  
Single Element ◽  
Glutathione Peroxidase Activity ◽  
Liver Copper ◽  
Foetal Mortality ◽  
Veterinary Surgeon ◽  
Total Life

Conception rate in ewes, mainly by reduction in early foetal mortality, have been improved by a range of individual supplementary trace elements (especially Se, but also Cu, Co, Mn and Zn) given prior to mating (Hidiroglou, 1979). Ritchie et al. (1997) has described significant improvements in liver copper concentration and blood glutathione peroxidase activity (GSHPx) in ewes given a single sustained-release multi-trace element and vitamin bolus which incorporates a grinder (‘Small-Trace’, Agrimin Ltd., Brigg DN20 0SP). This communication describes studies in the conception rate of ewes given this bolus at three grazing sites. Each flock was judged by the veterinary surgeon concerned to require routine trace element supplementation and which had previously been given by various combinations of injections, drenches, single element boluses and/or copper oxide needles.Each bolus contained 5.3g Cu, 50mg Se, 90mg Co, lOOmg I, 4.7g Zn and 3.3g Mn with (iu) 268 x 103 vitamin A, 54 x 103 vitamin D and 800 vitamin E. About one-half of each nutrient is released in the first 6-8 weeks; thereafter the rate slows and the total life of the bolus is c. 7 months. (Ritchie et al. 1997).

Hepatic copper concentration of steers grazing pastures on developed wet heath land in south-eastern Queensland

1968 ◽  
Vol 8 (35) ◽  
pp. 679 ◽  
Author(s):  
RJW Gartner ◽  
JG Young ◽  
PM Pepper
Keyword(s):  
Factorial Design ◽  
Cobalt Oxide ◽  
Subcutaneous Injection ◽  
Copper Concentration ◽  
Hepatic Copper ◽  
South Eastern ◽  
Liver Copper ◽  
Copper Therapy ◽  
Low Levels

A 2 X 2 factorial design was used to investigate the effects of copper and cobalt therapy of Hereford steers grazing Lotononis-Pangola pastures on the wet heath areas of coastal south-eastern Queensland. Copper was given as a subcutaneous injection of copper glycinate and cobalt as an intra- ruminal cobalt oxide pellet. Liver samples were obtained at three-monthly intervals for 18 months. The liver copper concentration of untreated animals decreased to low levels (<10 p.p.m.). Copper therapy increased (P<0.01) and cobalt therapy decreased (P<0.01) liver copper levels. There were, however, no significant differences in bodyweight gains.

scholarly journals Oxidative stress and neurobehavioural changes in rats following copper exposure and their response to MiADMSA and d-penicillamine

2019 ◽  
Vol 3 ◽  
pp. 239784731984478 ◽  
Author(s):  
Shaheen Quamar ◽  
Jayant Kumar ◽  
Awanish Mishra ◽  
SJS Flora
Keyword(s):  
Oxidative Stress ◽  
Copper Concentration ◽  
Copper Toxicity ◽  
Clinical Feature ◽  
Copper Level ◽  
Copper Exposure ◽  
Muscle Coordination ◽  
Contextual Fear ◽  
Liver Copper ◽  
Ameliorative Effect

An increase in copper concentration in body may lead to hepatolenticular degeneration which is considered as one clinical feature of Wilson’s disease. Chelation therapy using d-penicillamine is the preferred medical treatment for reducing the toxic effects of copper. However, a few shortcomings associated with d-penicillamine led us to search of an alternative antidote for copper toxicity. Monoisoamyl-2, 3-dimercaptosuccinic acid (MiADMSA), a potent arsenic chelator under clinical trial, has been reported to reduce system copper level. Thus, the present study was envisaged to explore the ameliorative effect of MiADMSA against copper toxicity. Copper pre-exposed animals (CuSO4.5H2O; 100 mg/kg; p.o., for 6 weeks) were segregated in different groups and were administered equimolar dose (0.3 mEq/kg/day; p.o.) of d-penicillamine and MiADMSA for 5 days. The effect of different treatments on spontaneous locomotor activity, muscle coordination, depression like behaviour and contextual fear memory was analysed using neurobehavioural battery test. Biochemical variables related to oxidative stress, zinc and copper concentration were determined in liver, kidney and brain. The results suggested that copper exposure led to oxidative stress in liver, kidney and blood, along with moderate effects in brain. Treatment with d-penicillamine and MiADMSA reduced liver copper load. MiADMSA produced more pronounced beneficial effect compared to d-penicillamine by increasing brain GPx activity. Our study suggests that MiADMSA might be equally effective as d-penicillamine in depleting body copper load. More detailed studies using different doses are required to suggest whether MiADMSA could be an alternative for d-penicillamine in reducing oxidative injury, neurobehavioural changes and depleting body copper burden.

OP034 RED BLOOD CELL, NOT PLASMA COPPER CONCENTRATION IS RELATED TO LIVER COPPER CONCENTRATION

2010 ◽  
Vol 5 (2) ◽  
pp. 14-15
Author(s):  
J. Logue ◽  
A. Duncan ◽  
C. Roxburgh ◽  
P. Horgan ◽  
D. O'Reilly
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Copper Concentration ◽  
Liver Copper ◽  
Plasma Copper

Observations on the copper metabolism of the domestic fowl and duck.

1961 ◽  
Vol 12 (4) ◽  
pp. 743 ◽  
Author(s):  
AB Beck
Keyword(s):  
Copper Sulphate ◽  
Domestic Fowl ◽  
Copper Concentration ◽  
Copper Metabolism ◽  
Basal Diet ◽  
Moderate Increase ◽  
Dietary Copper ◽  
Liver Copper ◽  
Copper Storage ◽  
The Relationship

Experiments have been carried out to determine whether the concentration of copper in the liver of the domestic fowl and duck can be raised by a moderate increase of dietary copper. Groups of both species were fed for 12 weeks on the same basal diet, to which was added copper sulphate to increase the copper intake two- and fivefold. No significant increase in the liver copper concentration was noted in either species. When copper was administered to both species by intravenous injection, it was rapidly excreted. mostly in the bile. In the fowl a significant amount was excreted through the caeca, but the experiments did not suggest that these organs were important in controlling copper storage. 5tudies on the relationship between h e r copper storage and age showed that there was a rapid increase in the duck after 3 weeks of age. No such changes were observed in the foul

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