MEADOWFOAM (Limnanthes alba) MEAL AS A FEEDSTUFF FOR DAIRY GOATS AND TOXICOLOGIC ACTIVITY OF THE MILK

1983 ◽  
Vol 63 (2) ◽  
pp. 391-398 ◽  
Author(s):  
R. D. WHITE ◽  
P. R. CHEEKE
Keyword(s):  
Thyroid Hormone ◽  
Dairy Goats ◽  
Lower Serum ◽  
Limnanthes Alba ◽  
Hormone Levels ◽  
Feeding Value ◽  
Serum Thyroid Hormone ◽  
Thyroid Hormone Levels ◽  
And Control ◽  
Receiving Water

The feeding value and goitrogenicity of meadowfoam (Limanthes alba L.) meal (MFM) as a feedstuff for dairy goats and the goitrogenic and toxicologic activity of milk from goats fed the meal were evaluated. Pregnant goats were fed a diet containing 30% raw MFM beginning 12–13 wk prior to parturition. Control goats received a similar diet without MFM. At parturition, MFM-fed does had slightly lower serum thyroid hormone levels than the controls. Kids from MFM-fed does had similar serum thyroid hormone levels at birth and lower levels at weaning compared to control kids. The MFM-fed and control dams had similar thyroid hormone levels at weaning. The growth rate of kids fed MFM was lower (P < 0.05) in the postweaning period than for controls. Milk from goats fed MFM was fed to growing rabbits. Rabbits fed this milk had heavier thyroid weights and higher mortality than rabbits receiving water or milk from control goats. No difference in serum thyroid hormone levels occurred. The results suggest that raw MFM should not be fed to lactating animals until the significance of milk-transferred goitrogenic agents has been fully assessed. Key words: Meadowfoam meal, Limnanthes, goats, glucosinolates, milk, rabbits

scholarly journals Serum Thyroid Hormone Levels in Healthy Children from Birth to Adulthood and in Short Children Born Small for Gestational Age

2012 ◽  
Vol 97 (9) ◽  
pp. 3170-3178 ◽  
Author(s):  
Annemieke J. Lem ◽  
Yolanda B. de Rijke ◽  
Hans van Toor ◽  
Maria A. J. de Ridder ◽  
Theo J. Visser ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Healthy Children ◽  
Hormone Levels ◽  
Short Children ◽  
Serum Thyroid Hormone ◽  
Thyroid Hormone Levels

scholarly journals Manipulating plasma thyroid hormone levels at hatching alters development of endothermy and ventilation in Pekin duck (Anas platyrhynchos domestica)

2020 ◽  
Vol 223 (22) ◽  
pp. jeb237701
Author(s):  
Tushar S. Sirsat ◽  
Edward M. Dzialowski
Keyword(s):  
Thyroid Hormone ◽  
Tidal Volume ◽  
Developmental Trajectory ◽  
Pekin Duck ◽  
Thyroid Peroxidase ◽  
Hormone Levels ◽  
Ventilation Frequency ◽  
Thyroid Hormone Levels ◽  
And Control

ABSTRACTAt hatching in precocial birds, there are rapid physiological and metabolic phenotypic changes associated with attaining endothermy. During the transition to ex ovo life, thyroid hormone levels naturally increase, peaking at hatching, and then decline. To better understand the role of the natural increase in thyroid hormone at hatching in regulating the developmental trajectory of the Pekin duck's endothermic phenotype, we examined development of O2 consumption (V̇O2) and ventilation (frequency, tidal volume and minute ventilation) while inhibiting the developmental increase in thyroid hormones that occurs at hatching via administration of the thyroid-peroxidase inhibitor methimazole (MMI) or accelerating the developmental increase via triiodothyronine (T3) supplementation. Animals were dosed only on day 24 of a 28-day incubation period and studied on incubation day 25, during external pipping (EP) and 1 day post-hatching (dph). On day 25, there was an increase in V̇O2 in the hyperthyroid treatment compared with the other two treatments. During the EP stage, there was a significant effect of thyroid status on V̇O2, with hyperthyroid V̇O2 being highest and hypothyroid V̇O2 the lowest. By 1 dph, the supplemented T3 and control animals had similar V̇O2 responses to cooling with comparable thermal neutral zones followed by increased V̇O2. Hypothyroid 1 dph hatchlings had a lower resting V̇O2 that did not increase to the same extent as the supplemented T3 and control animals during cooling. During EP, inhibiting the rise in T3 resulted in embryos with lower ventilation frequency and tidal volume than control and supplemented T3 embryos. At 1 dph, ventilation frequency of all animals increased during cooling, but tidal volume only increased in supplemented T3 and control hatchlings. Our data support the role of the late incubation increase in T3 in regulating the systemic development of endothermic metabolic capacity and associated control of ventilation occurring at hatching of the Pekin duck.

scholarly journals Tissue Thyroid Hormone Levels in Critical Illness

2005 ◽  
Vol 90 (12) ◽  
pp. 6498-6507 ◽  
Author(s):  
Robin P. Peeters ◽  
Serge van der Geyten ◽  
Pieter J. Wouters ◽  
Veerle M. Darras ◽  
Hans van Toor ◽  
...  
Keyword(s):  
Critical Illness ◽  
Thyroid Hormone ◽  
Hormone Treatment ◽  
Monocarboxylate Transporter ◽  
Total Serum ◽  
Tissue Specific ◽  
Hormone Levels ◽  
Serum T3 ◽  
Serum Thyroid Hormone ◽  
Thyroid Hormone Levels

Context: Pronounced alterations in serum thyroid hormone levels occur during critical illness. T3 decreases and rT3 increases, the magnitudes of which are related to the severity of disease. It is unclear whether these changes are associated with decreased tissue T3 concentrations and, thus, reduced thyroid hormone bioactivity. Patients and Study Questions: We therefore investigated, in 79 patients who died after intensive care and who did or did not receive thyroid hormone treatment, whether total serum thyroid hormone levels correspond to tissue levels in liver and muscle. Furthermore, we investigated the relationship between tissue thyroid hormone levels, deiodinase activities, and monocarboxylate transporter 8 expression. Results: Tissue iodothyronine levels were positively correlated with serum levels, indicating that the decrease in serum T3 during illness is associated with decreased levels of tissue T3. Higher serum T3 levels in patients who received thyroid hormone treatment were accompanied by higher levels of liver and muscle T3, with evidence for tissue-specific regulation. Tissue rT3 and the T3/rT3 ratio were correlated with tissue deiodinase activities. Monocarboxylate transporter 8 expression was not related to the ratio of the serum over tissue concentration of the different iodothyronines. Conclusion: Our results suggest that, in addition to changes in the hypothalamus-pituitary-thyroid axis, tissue-specific mechanisms are involved in the reduced supply of bioactive thyroid hormone in critical illness.

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