INFLUENCE OF CALCIUM AND PHOSPHORUS ON GROWTH AND SKELETAL DEVELOPMENT OF GROWING SWINE

1975 ◽  
Vol 55 (1) ◽  
pp. 147-164 ◽  
Author(s):  
C. E. DOIGE ◽  
J. H. L. MILLS ◽  
B. D. OWEN

A factorial design with three levels of calcium, three levels of phosphorus, two breeds and both sexes (72 pigs) was employed to study calcium and phosphorus deficiencies and imbalances in swine fed from 22 kg to 90 kg. Dietary levels of both minerals were 50, 100 and 150% of National Academy of Sciences–National Research Council (NAS–NRC) recommendations (1968). Data relating to performance and skeletal development were evaluated. Extreme Ca:P ratios in the diet impaired both performance and skeletal development. All changes were minimal if low levels of either element were accompanied by a Ca:P ratio near 1.25:1. Low calcium–high phosphorus rations resulted in parathyroid enlargement, reduced bone mass, increased numbers of osteoclasts and fibrous replacement of bone. In animals fed high calcium–low phosphorus rations, hypophosphatemia, reduced bone ash and overgrowth of epiphyseal plates were observed. Deviation of the nasal septum occurred but was not related to dietary levels of calcium or phosphorus. Levels of calcium and phosphorus presently recommended by NAS–NRC were consistent with optimal performance and adequate skeletal development.

2003 ◽  
Vol 83 (2) ◽  
pp. 205-211 ◽  
Author(s):  
A. Fortin ◽  
E. J. Clowes ◽  
A. L. Schaefer

This study was conducted to determine whether feeding gilts (1) at or above their National Academy of Sciences-National Research Council (NAS-NRC 1998) requirements during gestation, and (2) to lose a moderate (~10%) or large (~17%) amount of maternal protein during lactation had a residual effect on their progeny’s growth, carcass characteristics and pork quality at market weight. From each litter, the heaviest and lightest barrows and gilts were selected. The progeny of gilts fed above their requirements during gestation, and those that lost the least body protein during lactation were heavier at weaning; +0.3 kg (P < 0.05) and +0.5 kg (P = 0.01), respectively. However, these liveweight differences, which were associated with the gestation and lactation effects, were no longer evident (P > 0.05) at day 35 or 85 post-weaning. But at slaughter, these animals had thinner (P < 0.01) fat thickness and higher (P < 0.05) predicted salable meat yield. Independently of the gestation and lactation treatments, and compared to the low-weaning-weight pigs, the high- weaning-weight pigs maintained their weight advantage (P < 0.01 at day 35 (+ 2.8 kg) and day 85 (+ 5.4 kg) post-weaning), took 4.5 fewer days (P < 0.01) to reach market weight, but had similar (P > 0.05) carcass characteristics and pork quality. Key words: Gilts, gestational and lactational protein, litter, growth, carcass characteristics and meat quality


2019 ◽  
Vol 22 (6) ◽  
pp. 757-760 ◽  
Author(s):  
Margaret Gatz ◽  
Brenda L. Plassman ◽  
Caroline M. Tanner ◽  
Samuel M. Goldman ◽  
Gary E. Swan ◽  
...  

AbstractThe National Academy of Sciences-National Research Council (NAS-NRC) Twin Registry is one of the oldest, national population-based twin registries in the USA. It comprises 15,924 White male twin pairs born in the years 1917–1927 (N = 31.848), both of whom served in the armed forces, chiefly during World War II. This article updates activities in this registry since the most recent report in Twin Research and Human Genetics (Page, 2006). Records-based data include information from enlistment charts and Veterans Administration data linkages. There have been three major epidemiologic questionnaires and an education and earnings survey. Separate data collection efforts with the NAS-NRC registry include the National Heart, Lung, and Blood Institute (NHLBI) subsample, the Duke Twins Study of Memory in Aging and a clinically based study of Parkinson’s disease. Progress has been made on consolidating the various data holdings of the NAS-NRC Twin Registry. Data that had been available through the National Academy of Sciences are now freely available through National Archive of Computerized Data on Aging (NACDA).


2020 ◽  
Vol 31 (5) ◽  
pp. 466-470
Author(s):  
Erika Calvano Küchler ◽  
Raquel Fernanda Gerlach ◽  
Arthur S Cunha ◽  
Lucas A Ramazzotto ◽  
Paula Porto Spada ◽  
...  

Abstract Homeostasis between salivary calcium and phosphorus is important for maintaining oral health. The aim of this study was to evaluate if polymorphisms in ESR1 (Estrogen Receptor Alpha), ESR2 (Estrogen Receptor Beta) and miRNA17 (microRNA17) are associated with calcium and phosphorus levels in saliva. Saliva from 276 12-year-old children were collected by masticatory stimulation and calcium and phosphorus levels were determined by Mass Spectrometry. Genomic DNA was extracted from remaining saliva and genetic polymorphisms in ESR1 (rs12154178, rs1884051, rs9340799 and rs2234693), in ESR2 (rs4986938 and rs1256049) and in miRNA17 (rs4284505) were genotyped using TaqMan chemistry and a real-time PCR equipment. Statistical differences in genotype and allele distributions between ‘low’ and ‘high’ calcium and phosphorus levels were determined using chi-square or Fisher´s exact tests. The analysis was also adjusted by sex (alpha of 5%). ESR1 rs9340799 had the less common genotype associated with higher calcium levels (p=0.03). The less common allele of ESR1 rs1884051 was associated with lower phosphorus levels (p=0.005) and there was an excess of heterozygotes for miRNA17 rs4284505 among individuals with lower calcium levels (p=0.002), both adjusted by sex. This study provides evidence that genetic polymorphisms in ESR1 and miRNA17 are involved in determining salivary calcium and phosphorus levels.


1989 ◽  
Vol 33 (10) ◽  
pp. 568-570
Author(s):  
Harold P. Van Cott

The Committee on Human Factors, a standing committee of the National Academy of Sciences/National Research Council (NAS/NRC), advises its sustaining sponsors and other requesting organizations on issues involved in the design of socio-technical systems and on the research and methods needed to help enhance their operability and safety. This paper describes the origins, purposes, operations and program of the committee and emphasizes the special attributes of this and other NAS/NRC commtittees.


1992 ◽  
Vol 25 (9) ◽  
pp. 49-57
Author(s):  
W. F. Garber

Required monitoring of the physical, biological and chemical condition of the nearshore waters of the ocean receiving treated wastewaters has been underway in the U.S.A. since 1955 or about 35 years. When established the stated intent had been to utilize the information obtained to evaluate the effects of the diffusion of wastewaters upon the beneficial values of these receiving waters. That is upon the food web including game and food fish; upon water contact sports uses; upon aesthetics; and upon the local, regional, and worldwide ecology. To this end original requirements had included a provision that the regulatory agency reduce the data obtained from the monitoring effort to information useful to themselves as well as to facility design and operational authorities. Inasmuch as the monitoring effort in 1989 was using funds in excess of 130 million dollars per year and had a 35 year data base, the Marine Board of the National Research Council - National Academy of Sciences: National Academy of Engineering established committees of scientists to evaluate the progress of the national monitoring effort and of the longest and most complete program of the Southern California Bight. It was found that the essential portion of the program, that of reducing the data obtained to usable information, had not been carried on so that approximately 35 years of data existed with little to zero information. In addition the data existed in pools of intensive samplings around discharge points with very little overall study of the coastal waters. Whether the discharge points were significantly different from the “normal” coastal waters was not really known because “normal” was not known. The Committees recommended procedures to follow to rectify these basic problems including reallocation of current funding to cover the research, control, design and operational needs. Their findings are summarized in the paper.


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