scholarly journals RELATIONSHIP BETWEEN INORGANIC PHOSPHORUS AND INORGANIC CALCIUM IN CHICKEN BLOOD PLASMA

1969 ◽  
Vol 49 (2) ◽  
pp. 193-195 ◽  
Author(s):  
E. E. Gardiner

Male crossbred broiler-type chickens were fed graded levels of dietary phosphorus from hatching to 4 weeks of age. Plasma inorganic phosphorus and plasma inorganic calcium were determined on aliquots of blood plasma samples taken when the chickens were 4 weeks of age. The level of plasma inorganic phosphorus decreased when the chickens were fed low levels of dietary phosphorus. The level of plasma inorganic calcium was inversely related to the plasma inorganic phosphorus level. Regression equations were different for each of the four dietary phosphorus levels fed. The sum of plasma inorganic phosphorus and plasma inorganic calcium was very similar for the four treatments.

1970 ◽  
Vol 42 (1) ◽  
pp. 8-20
Author(s):  
Vappu Kossila ◽  
Paavo Niemelä ◽  
Erkki Koskenkorva

Blood mineral studies were carried out in the dairy herd of the Viik Experimental Farm, in which parturient paresis has been successfully prevented by intramuscular injections of vitamin D3 (2 X 5 million I.U.). The material consisted of 41 cows from which 207 blood samples had been taken in 1963 and 12 cows (6 controls, 6 vitamin D injected cows) from which 72 blood samples had been taken in 1969. All cows were either dry and pregnant or lactating and nonpregnant. Compared to values obtained during the dry period, the serum calcium level was only slightly lower shortly after calving. The calcium level increased in the vitamin D treated cows during the ascending phase of lactation, whereas both the calcium and inorganic phosphorus levels remained relatively low in the control cows, respectively. The highest mean magnesium levels occurred during the 2nd and 3rd weeks of lactation. The serum calcium level was higher during the grazing period than during the indoor feeding period. Inorganic phosphorus remained at a relatively high level in younger cows during the grazing period, whereas a significant decrease was noted in the phosphorus level of older cows, respectively. The lowest magnesium values were noted in May, i.e. already before the beginning of the pasture season, the concentration increasing towards the end of the grazing period especially in younger cows. As a whole, younger cows had slightly higher mean serum calcium and magnesium levels and significantly higher inorganic phosphorus levels compared to older cows. The effect of age on the inorg. phosphorus level appeared to be more marked in dry cows and during the grazing period than in lactating cows and during the winter feeding period. Special attention has been paid to the blood mineral values of four individual cows suffering from various illnesses during the study period.


1967 ◽  
Vol 18 (4) ◽  
pp. 635 ◽  
Author(s):  
FM Tomas ◽  
RJ Moir ◽  
M Somers

Rumen fluid, serum, and parotid salivary inorganic phosphorus concentrations in sheep given four levels of dietary phosphorus (0.42–4.02 g/day) were directly related to phosphorus intake. There was a very high correlation (r = +0.91; P < 0.001) between inorganic phosphorus concentrations in centrifuged rumen fluid and in parotid saliva. Serum inorganic phosphorus concentrations were positively correlated with those of saliva (r = +0.64; P< 0.05) and also with those in centrifuged rumen fluid (r = +0.75; P<0.01). The range in the mean daily saliva volumes collected from one parotid gland in each sheep was 3.2 to 4.2 l/day. The calculated minimum total salivary phosphorus secretion ranged from 3.0 g/day on the lowest dietary phosphorus intake to 5.3 g/day on the highest, the corresponding ratios of salivary to dietary phosphorus being from 7.24 to 1 .32 g/g. It appeared that salivary phosphorus was the major source of phosphorus to the rumen, and was also the principal determinant of rumen fluid inorganic phosphorus levels.


2006 ◽  
Vol 19 (1) ◽  
Author(s):  
K. AMBASANKAR ◽  
S. AHAMAD ALI ◽  
J. SYAMA DAYAL

Six semi-purified diets were formulated with supplemented phosphorus levels of 0, 0.5, 1.0, 1.5, 2.0 and 2.5% at a fixed calcium level of 1.25% and the effect of dietary phosphorus on growth, FCR, body phosphorus and its excretion in shrimp Penaeus monodon was studied. The results of a 45 day feeding trial, in triplicate, on the juveniles of P. monodon (initial average live –weight 2.54 ±0.28g) had shown that phosphorus is indispensable in the diet and the best performance (147.3 and 154.5% increase in live-weight and 1.44 and 1.57 FCR) was recorded by the diet supplemented with 1.0 and 1.5% phosphorus which was significantly (P<0.05) higher than the performance of the other diets tested. Higher phosphorus supplementation suppressed growth and increased FCR. The shrimp maintained body phosphorus and calcium levels in a ratio of 1:3 irrespective of dietary levels of phosphorus. There was no significant change in the proximate composition of post feeding trial shrimp. Phosphorus excretion in faeces of P. monodon increased proportionately with dietary phosphorus while the excretion level far exceeded the body phosphorus level in the shrimp fed with diets having supplemented phosphorus level above 1.5%. Even the shrimp fed with 0% phosphorus diet had 0.10% phosphorus in their faeces. The phosphorus levels in shrimp feeds vis-a-vis its excretion into aquaculture environment have been discussed.


1960 ◽  
Vol 54 (2) ◽  
pp. 235-242 ◽  
Author(s):  
D. H. L. Rollinson ◽  
R. M. Bredon

Studies have been made on calcium and inorganic phosphorus in pasture grass and their relationship to blood levels in Zebu cattle.Excitement, adrenaline injections and fatigue were investigated as possible causes of variations in the inorganic-phosphorus levels of the blood of Zebu cattle.Sudden rainfall appeared to cause alterations in the inorganic phosphorus levels of blood. This hypothesis, when tested on two separate batches of cattle on two occasions, showed that there was a highly significant relationship between water intake and the level of inorganic phosphorus of Zebu cattle blood.Water starvation caused a steady increase in the level of inorganic phosphorus and when water was available for the cattle to drink the inorganic phosphorus level fell rapidly to a subnormal level before returning to normal. These results are discussed in the light of the available literature.


Author(s):  
Linshuoshuo Lv ◽  
Ding Ye ◽  
Jie Chen ◽  
Yu Qian ◽  
Alan Nuo Fu ◽  
...  

Abstract Background Recent observational studies have suggested that circulating phosphorus levels are positively associated with risk of prostate cancer. However, little is known about the causal direction of the association. Objective To explore the potential causal relationship between circulating phosphorus and risk of prostate cancer, we conducted a Mendelian randomization (MR) study. Design Summary statistics of prostate cancer were obtained from a meta-analysis of genome-wide association studies (GWAS) consisting of 79,148 cases and 61,106 controls. Single nucleotide polymorphisms (SNP) associated with serum phosphorus level were selected from a GWAS of 291,408 individuals from the UK Biobank. MR analysis was performed using the inverse-variance weighted (IVW) method, supplemented with simple-median, weighted-median, maximum likelihood-based, MR-Egger regression and MR-PRESSO test. We also performed a meta-analysis of observational studies to assess the associations of dietary phosphorus intake and serum phosphorus level with risk of prostate cancer. Results In the MR analysis, a total of 125 independent SNPs associated with serum phosphorus levels were used as instrumental variables. Genetically predicted serum phosphorus levels were associated with a 19% increased risk of prostate cancer (95% confidence interval (CI): 9%, 31%) per one SD increment of serum phosphorus by IVW (P = 1.82 × 10–4). Sensitivity analyses using alternative MR methods produced similar positive associations, and no evidence of pleiotropy was detected by MR-Egger regression (P = 0.422). For meta-analysis, eight studies for dietary phosphorus intake and four for serum phosphorus levels were included involving a total of 669,080 participants. Consistently, high dietary phosphorus intake and serum phosphorus levels were associated with an 8% (95% CI: 4%, 12%) and 7% (95% CI: 1%, 14%) increase in prostate cancer risk, respectively. Conclusions Our study suggested a potential causal relationship between circulating phosphorus and risk of prostate cancer. Further studies are warranted to elucidate the underlying mechanism of phosphorus in the development of prostate cancer.


1973 ◽  
Vol 13 (65) ◽  
pp. 625
Author(s):  
RDH Cohen

The effect of phosphorus supplements of 35 and 70 g per head per week on the calcium and phosphorus contents of bone and hair and on plasma inorganic phosphorus levels of steers was compared with those of unsupplemented steers which grazed carpet grass (Axonopus affinis) pasture of low phosphorus content at Grafton, New South Wales. The supplements had no effect on plasma inorganic phosphorus concentration. Hair phosphorus content was not affected by either dietary phosphorus or season. Hair calcium was not influenced by pasture calcium but was related to season, with highest levels in summer and lowest in winter. Supplementation increased the amount of phosphorus in dry fat-free rib-bone (P < 0.05) but this effect was not apparent in the first three months of supplementation. The amount of calcium in bone (Y) was influenced by pasture calcium content (X1) and bone phosphorus content (X2). This relationship was described by the equation: Y = 51.0 + 140.81X1 - 3.33X2(R2 = 0.71; P < 0.001) It is suggested that bone phosphorus levels below 14.3, 13.5, and 12.7 per cent of dry fat-free bone may represent a phosphorus deficiency state in 15-27-month-old steers when pasture calcium levels are 0.18, 0.15, and 0.12 per cent respectively. Further, when estimates of the calcium status of beef steers are made from measurements of bone calcium content, corrections should be applied for bone phosphorus content. It is concluded that measurement of bone phosphorus and calcium provides the most sensitive indication of the phosphorus and calcium status of beef cattle and that when phosphorus supplementation has no effect on liveweight of beef steers its effect on mineralization of bone tissue may justify its use, particularly in areas where poor bone development and lameness occur.


1973 ◽  
Vol 13 (65) ◽  
pp. 625
Author(s):  
RDH Cohen

The effect of phosphorus supplements of 35 and 70 g per head per week on the calcium and phosphorus contents of bone and hair and on plasma inorganic phosphorus levels of steers was compared with those of unsupplemented steers which grazed carpet grass (Axonopus affinis) pasture of low phosphorus content at Grafton, New South Wales. The supplements had no effect on plasma inorganic phosphorus concentration. Hair phosphorus content was not affected by either dietary phosphorus or season. Hair calcium was not influenced by pasture calcium but was related to season, with highest levels in summer and lowest in winter. Supplementation increased the amount of phosphorus in dry fat-free rib-bone (P < 0.05) but this effect was not apparent in the first three months of supplementation. The amount of calcium in bone (Y) was influenced by pasture calcium content (X1) and bone phosphorus content (X2). This relationship was described by the equation: Y = 51.0 + 140.81X2 - 3.33X2(R2 = 0.71; P < 0.001) It is suggested that bone phosphorus levels below 14.3, 13.5, and 12.7 per cent of dry fat-free bone may represent a phosphorus deficiency state in 15-27-month-old steers when pasture calcium levels are 0.18, 0.15, and 0.12 per cent respectively. Further, when estimates of the calcium status of beef steers are made from measurements of bone calcium content, corrections should be applied for bone phosphorus content. It is concluded that measurement of bone phosphorus and calcium provides the most sensitive indication of the phosphorus and calcium status of beef cattle and that when phosphorus supplementation has no effect on liveweight of beef steers its effect on mineralization of bone tissue may justify its use, particularly in areas where poor bone development and lameness occur.


2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Navjot Kaur ◽  
Himansu Mahapatra ◽  
Neera Sharma ◽  
Lalit Pursnani ◽  
Muthukumar B ◽  
...  

Abstract Background and Aims There were paucity of clinical evidence on target serum phosphorus levelsin early CKD. Present longitudinal study finds target phosphorus level and its association with FGF 23 in three different hyperphosphatemia managements groups. Method This one year, prospective, randomised controlled, open labelled study was conducted among three equally allocated treatment groups in 120 screened early CKD patients.Group1 Dietary phosphorus modificationn40; Group2 calcium-based phosphate bindersn40 and Group3 non calcium-based phosphate bindersn40.Three monthly dietary assessment, MDRD e-GFR, phosphorus, calcium, iPTH, Alkaline phosphatise and six monthly FGF23, 2D Echocardiography, X ray of chest and abdomen were performed. Association of three categories of phosphorus level up to 3.9 mg/dl, 4 to 5mg/dl and &gt;5mg/dl, rate of progression of all parameters and correlation with FGF 23among all three groups were studied. Results At baseline, all clinical and biochemical parameters were equally distributed with a controlled nutritional phosphate among all groups. There was no significant difference of FGF23 in all the three categories of phosphorus level among all groups. Association of serum phosphorus at the level of 5 mg/dl was there with iPTH and e-GFR at one year. Over one year there were significant decline in serum phosphorus levels in Group1 p 0.02, Group2 p 0.00,Group3p 0.05;FGF23 was declined significantly only in group3p 0.00.Correlation of FGF23 was positive and negative with iPTH r 0.19,p 0.03 and e-GFR r-0.30, p 0.00respectively but not with phosphorus p0.13 Conclusion Serum phosphorus levels up to 5mg/dl has no effect on FGF 23 at early CKD stages. Although different treatment groups have significant phosphorus reduction, non-calcium phosphate binder has major impact on FGF23 reduction.


Sign in / Sign up

Export Citation Format

Share Document