THE METABOLIC FECAL NITROGEN EXCRETION OF THE PIG AS INFLUENCED BY THE TYPE OF FIBRE IN THE RATION AND BY BODY WEIGHT

1957 ◽  
Vol 37 (1) ◽  
pp. 106-113 ◽  
Author(s):  
F. Whiting ◽  
L. M. Bezeau

Nitrogen balance studies were carried out on growing pigs (15 to 60 kg. body weight) using protein-low rations (approximately 0.3 per cent) to study the influence of body weight and type of fibre in the ration upon metabolic fecal and endogenous urinary nitrogen (N). The types and amounts of fibre used were: pure wood cellulose (Solka-Floc), 7 and 14 per cent of the ration; methocel, 7 and 14 per cent of the ration; and oat hulls, 14 and 28 per cent of the ration.Type and amount of fibre significantly affected the metabolic fecal N excretion of the pig, whether expressed on the basis of dry matter (D.M.) intake or fecal D.M. output. Wood cellulose (Solka-Floc) caused the greatest, and methocel the least, fecal N excretion per unit of D.M. intake. Oat hulls were intermediate.Fecal N excretion varied inversely with the 0.3 power of body weight between the body weights of approximately 15 and 60 kg.Endogenous urinary N in one experiment varied with approximately the 1.0 power of body weight, and in a second experiment with the 0.2 power of body weight. It was not possible in these experiments to determine the factors that influenced endogenous urinary N excretion.

1992 ◽  
Vol 68 (2) ◽  
pp. 463-472 ◽  
Author(s):  
S. Furuya ◽  
Y. Kaji

The effects of level of feed intake (0.8, 1.2 and 1.6 kg/d) and body-weight of the pig (49 and 92 kg) in Expt 1, and dietary neutral-detergent fibre (NDF; 30, 60, 90, 120 and 150 g/kg) in Expt 2 on the endogenous ileal flow of amino acids (AA) and nitrogen were studied with protein-free diets into which purified wood cellulose was incorporated at the expense of maize starch. In Expt 1, one of the protein-free diets containing 90 g NDF/kg was used. Female pigs were fitted with a simple ‘T’ cannula at the terminal ileum. In Expt 1, the endogenous ileal AA and N flow, expressed as g/kg dry matter (DM) intake, decreased significantly (P < 0.05) with increasing DM intake, except for proline. By contrast, the values expressed as g/d remained constant. There was no significant difference in endogenous ileal flow (P > 0.05) between initial body-weights of 45 and 90 kg except for histidide, isoleucine, phenylalanine, threonine, valine and serine, in which the ileal flow determined at the higher body-weight was significantly higher (P < 0.05). In Expt 2, the effects of dietary cellulose levels on the endogenous ileal flow of AA and N were not significant (P > 0.05), although the values tended to increase as dietary cellulose levels increased for most AA and for N. It is concluded that the daily endogenous ileal flow of AA and N remains relatively similar at different DM intake and cellulose levels. Therefore, correction of apparent ileal digestibility of AA and N to the true ileal digestibility should be made with the endogenous ileal flow values expressed on a daily amount basis, not the values expressed on a DM intake basis


1957 ◽  
Vol 37 (2) ◽  
pp. 152-156 ◽  
Author(s):  
H. M. Cunningham ◽  
G. J. Brisson

Daily observations were made on the fecal and urinary nitrogen excretions of four calves fed nitrogen-free diets during the second and fifth weeks after birth. The endogenous urinary nitrogen excretion was equivalent to 65.3 mg. per kg. of body weight (W) per day or 186 mg. per kg. W0.72. The metabolic fecal nitrogen excretion averaged 44.0 mg. per kg. of body weight per day or 0.334 per cent of the dry matter intake.


1966 ◽  
Vol 20 (1) ◽  
pp. 103-111 ◽  
Author(s):  
K. L. Blaxter ◽  
F. W. Wainman

1. The metabolism of seventeen steers was determined on forty-nine occasions during fasts of either 112 or 136 h duration.2. Faeces continued to be produced during fasts of up to 136 h duration at rates which were 15–20% of those noted before the fasts began.3. Carbon dioxide production and oxygen consumption fell continuously throughout with animals weighing less than 200 kg but changed little after 88 h in animals weighing more than 200 kg. Methane production was considerably reduced during fasting but did not disappear. Urinary nitrogen excretion changed very little. Of the total loss of energy from the body, the loss of protein accounted for 25%. This was unaffected by age or size of animal.4. With individual Ayrshire steers, metabolism increased during growth with body-weight raised to the power 0.68±0.05. No greater precision of estimate was obtained from logarithmic regressions of metabolism on body-weight than from linear ones.5. Seven Ayrshire steers had a mean fasting metabolism of 100±1.6 kcal/kg W0.73 24 h, eight Black cattle of the Aberdeen Angus type a fasting metabolism of 81±1.5 kcal/kg W0.73 24 h and two Ayrshire x Beef Shorthorn steers a fasting metabolism of 96±2.9 kcal/kg W0.73 24 h. Variation in the fasting metabolism of an individual steer from time to time, expressed as a coefficient of variation, was ±7.4%.6. The results are discussed in relation to interspecies generalizations about the relation between fasting metabolism and body-weight.


1957 ◽  
Vol 37 (1) ◽  
pp. 95-105 ◽  
Author(s):  
F. Whiting ◽  
L. M. Bezeau

Nitrogen balance experiments were carried out with growing Yorkshire barrows to determine the influence of level of fibre (5, 10, and 15 per cent wood cellulose) in the ration, and weight of pig (15, 30, 45, and 60 kg.) on the metabolic fecal nitrogen (M.F.N.) excretion. Semi-synthetic rations containing 0.3, 5.4, 9.4, 14.0, 18.0, and 22.0 per cent protein were fed. The source of the protein was a mixture of wheat, skimmilk powder, and fishmeal. M.F.N. by direct determination on the protein-low ration (0.3 per cent protein) was compared with M.F.N. determined by extrapolation to zero protein from the other rations.An increase in the level of fibre in the ration significantly (p < 0.01) increased the M.F.N. excretion and decreased the apparent and true digestibility of the protein but had no effect on the biological value (B.V.) of the protein. As the pigs increased in weight from 15 to 50 kg., the M.F.N. excretion, per 100 gm. dry matter (D.M.) consumed, decreased in proportion to the 0.3 power of body weight, the apparent digestibility of the protein increased, and the B.V. of the protein decreased. M.F.N, per 100 gm. D.M. consumed, apparent digestibility, and B.V. of the protein did not change significantly between body weights of 50 and 65 kg.There was no significant difference between M.F.N. determined by extrapolation to zero N intake and M.F.N. determined directly by feeding a protein-low (0.3 per cent protein) ration, when the rations contained the same percentage of cellulose. The M.F.N. (gm. per 100 gm. D.M. intake) for pigs weighing an average 37 kg. was 0.10, 0.13 and 0.14 for rations containing 5, 10, and 15 per cent cellulose, respectively.Since weight of pig and the level of fibre in the ration significantly influenced the M.F.N. excretion, the latter should be determined, either directly or by extrapolation, using rations of the same fibre content and pigs of the same body weight as are used in determining the true digestibility and B.V. of proteins.


1972 ◽  
Vol 79 (2) ◽  
pp. 323-329 ◽  
Author(s):  
R. Paquay ◽  
R. De Baere ◽  
A. Lousse

SUMMARYThe dietary and individual factors influencing the utilization of digestible nitrogen in the dry cow were studied with numerous rations fed to Friesian cows kept in metabolism stalls.Urinary nitrogen excretion and nitrogen balance were above all influenced by the level of digestible nitrogen intake. They are also correlated to metabolizable energy and digestible potassium intakes.Endogenous urinary nitrogen, estimated by extrapolation, was 30·6 mg N/kg body weight/d or 0·169 W0·73 g/d with the rations meeting approximately the energy maintenance requirements of the cow.The changes in diet accounted for 80% of the variability of nitrogen balance.A method was worked out for calculating the body condition of the cow from the live-weight variations.The changes in body condition accounted for 11% of the variability of nitrogen balance.


2014 ◽  
Vol 84 (1-2) ◽  
pp. 5-11 ◽  
Author(s):  
Eun Y. Jung ◽  
Sung C. Jun ◽  
Un J. Chang ◽  
Hyung J. Suh

Previously, we have found that the addition of L-ascorbic acid to chitosan enhanced the reduction in body weight gain in guinea pigs fed a high-fat diet. We hypothesized that the addition of L-ascorbic acid to chitosan would accelerate the reduction of body weight in humans, similar to the animal model. Overweight subjects administered chitosan with or without L-ascorbic acid for 8 weeks, were assigned to three groups: Control group (N = 26, placebo, vehicle only), Chito group (N = 27, 3 g/day chitosan), and Chito-vita group (N = 27, 3 g/day chitosan plus 2 g/day L-ascorbic acid). The body weights and body mass index (BMI) of the Chito and Chito-vita groups decreased significantly (p < 0.05) compared to the Control group. The BMI of the Chito-vita group decreased significantly compared to the Chito group (Chito: -1.0 kg/m2 vs. Chito-vita: -1.6 kg/m2, p < 0.05). The results showed that the chitosan enhanced reduction of body weight and BMI was accentuated by the addition of L-ascorbic acid. The fat mass, percentage body fat, body circumference, and skinfold thickness in the Chito and Chito-vita groups decreased more than the Control group; however, these parameters were not significantly different between the three groups. Chitosan combined with L-ascorbic acid may be useful for controlling body weight.


2020 ◽  
Vol 20 (8) ◽  
pp. 1262-1267
Author(s):  
Haojun Yang ◽  
Hanyang Liu ◽  
YuWen Jiao ◽  
Jun Qian

Background: G protein-coupled bile acid receptor (TGR5) is involved in a number of metabolic diseases. The aim of this study was to identify the role of TGR5 after Roux-en-Y gastric bypass (GBP). Methods: Wild type and TGR5 knockout mice (tgr5-/-) were fed a high-fat diet (HFD) to establish the obesity model. GBP was performed. The changes in body weight and food intake were measured. The levels of TGR5 and peptide YY (PYY) were evaluated by RT-PCR, Western blot, and ELISA. Moreover, the L-cells were separated from wild type and tgr5-/- mice. The levels of PYY in L-cells were evaluated by ELISA. Results: The body weights were significantly decreased after GBP in wild type mice (p<0.05), but not tgr5-/- mice (p>0.05). Food intake was reduced after GBP in wild type mice, but also not significantly affected in tgr5-/- mice (p>0.05). The levels of PYY were significantly increased after GBP compared with the sham group (p<0.05); however, in tgr5-/- mice the expression of PYY was not significantly affected (p>0.05). After INT-777 stimulation in L-cells obtained from murine intestines, the levels of PYY were significantly increased in L-cells tgr5+/+ (p<0.05). Conclusion: Our study suggests that GBP up-regulated the expression of TGR5 in murine intestines, and increased the levels of PYY, which further reduced food intake and decreased the body weight.


Author(s):  
P. M, Lunagariya ◽  
R. S. Gupta ◽  
S. V. Shah ◽  
Y. G. Patel

The study was planned to evaluate the effect of exogenous fibrolytic enzymes (EFE) supplementation for 56 days @ 240 mg/kg total mixed ration (TMR) on digestibility of dry matter and nutrients in dairy cows. Six dry non-pregnant cows were assigned in each treatment with and without EFE. The digestibility trial of seven days was conducted after 49 days of feeding. Dry matter and nutrients intake of cows was not influenced by EFE. The supplementation of EFE had improved digestibility of dry matter, organic matter, crude fiber, neutral detergent fiber, cellulose (p less than 0.01), as well as digestibility of nitrogen-free extract and acid detergent fiber, was also higher (pless than 0.05). The body weight gain of cows was higher on the supplementation of EFE in TMR. The study concluded that feeding exogenous fibrolytic enzymes (240 mg/kg) supplemented TMR improved digestibility of dry matter and nutrients, which was reflected as higher body weight gain in dry non-pregnant Gir and crossbred dairy cows.


Critical Care ◽  
2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Pierre Singer ◽  
Itai Bendavid ◽  
Ilana BenArie ◽  
Liran Stadlander ◽  
Ilya Kagan

Abstract Background and aims Combining energy and protein targets during the acute phase of critical illness is challenging. Energy should be provided progressively to reach targets while avoiding overfeeding and ensuring sufficient protein provision. This prospective observational study evaluated the feasibility of achieving protein targets guided by 24-h urinary nitrogen excretion while avoiding overfeeding when administering a high protein-to-energy ratio enteral nutrition (EN) formula. Methods Critically ill adult mechanically ventilated patients with an APACHE II score > 15, SOFA > 4 and without gastrointestinal dysfunction received EN with hypocaloric content for 7 days. Protein need was determined by 24-h urinary nitrogen excretion, up to 1.2 g/kg (Group A, N = 10) or up to 1.5 g/kg (Group B, N = 22). Variables assessed included nitrogen intake, excretion, balance; resting energy expenditure (REE); phase angle (PhA); gastrointestinal tolerance of EN. Results Demographic characteristics of groups were similar. Protein target was achieved using urinary nitrogen excretion measurements. Nitrogen balance worsened in Group A but improved in Group B. Daily protein and calorie intake and balance were significantly increased in Group B compared to Group A. REE was correlated to PhA measurements. Gastric tolerance of EN was good. Conclusions Achieving the protein target using urinary nitrogen loss up to 1.5 g/kg/day was feasible in this hypercatabolic population. Reaching a higher protein and calorie target did not induce higher nitrogen excretion and was associated with improved nitrogen balance and a better energy intake without overfeeding. PhA appears to be related to REE and may reflect metabolism level, suggestive of a new phenotype for nutritional status. Trial registration 0795-18-RMC.


1985 ◽  
Vol 249 (2) ◽  
pp. R159-R165 ◽  
Author(s):  
G. L. Florant ◽  
A. K. Lawrence ◽  
K. Williams ◽  
W. A. Bauman

Fasting plasma insulin (PI) and glucose (PG) concentrations were measured throughout the body weight cycle of marmots. Animals gained weight during summer, and in late fall body weight peaked, after which they ceased feeding. Each month euthermic animals were injected intra-arterially with either dextrose (500 mg/kg) or porcine insulin (0.1 U/kg), and blood samples were collected over the subsequent 2 h. During weight gain fasting PI concentration and pancreatic B-cell response to injected dextrose increased markedly. Maximal insulin release to a dextrose challenge was measured during peak body weight or when body weight initially began to decline. The PG concentration after exogenous insulin administration was slight (less than 10%) in the fall but increased approximately 25% in the spring after marmots lost weight. Basal PG levels were not significantly different throughout the year. Basal fasting PI concentrations were significantly higher during the fall (P less than 0.01). It is suggested that in the fall, when marmots are obese, hyperinsulinemia and peripheral insulin resistance appear. Furthermore, in two animals with an increase in body weight of approximately 30% or less over the summer, peripheral resistance was demonstrable, albeit not as marked as in animals that appropriately doubled their body weights when given food ad libitum. Thus we hypothesize that factors other than adiposity, i.e., food intake, central nervous system input to the pancreatic B-cell, and/or changes in B-cell sensitivity to PG, may contribute to the observed peripheral insulin resistance and may be involved in body weight regulation.


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