Changes in serum concentrations of folates, pyridoxal, pyridoxal-5-phosphate and vitamin B12 during lactation of dairy cows fed dietary supplements of folic acid

1999 ◽  
Vol 79 (1) ◽  
pp. 107-114 ◽  
Author(s):  
C. L. Girard ◽  
J. J. Matte
Keyword(s):  
Folic Acid ◽  
Dairy Cows ◽  
Dietary Supplements ◽  
Dairy Cow ◽  
Vitamin B ◽  
Early Lactation ◽  
Serum Concentrations ◽  
Ruminal Microorganisms ◽  
Time Parity ◽  
B Complex Vitamins

The present experiment was undertaken to determine the effects of dietary supplements of folic acid (FA) administered from 4 wk prepartum to 305 d of lactation on serum concentrations of folates, vitamin B12, pyridoxal-5-phosphate (P-5-P) and pyridoxal. In addition, concentrations of blood hemoglobin and packed cell volume (PCV) were determined. Sixty-three Holstein cows were assigned to 22 incomplete blocks according to lactation number, milk production and body weight (BW). Within each block, cows received 0, 2 and 4 mg FA d−1 kg−1 BW. Dietary supplements of FA increased serum concentrations of folates (time × FA, P = 0.0001); the highest concentrations were observed during the first two months of lactation in cows fed supplementary FA. The lowest serum concentrations of vitamin B12 were also observed during the first two months of lactation, and the concentrations were lower in primiparous than in multiparous cows (time × parity, P = 0.03). Serum concentrations of P-5-P and pyridoxal were not affected by the dietary supplements of FA (P > 0.1). In multiparous cows, dietary supplements of FA had no effect on changes of hemoglobin and PCV during the lactation (time × FA, P > 0.13). In primiparous cows, PCV and hemoglobin were lower in control cows at parturition whereas by 24 wk of lactation, they were higher in cows fed the highest amount of FA. The lowest values of hemoglobin and PCV were observed during the first two months of lactation. These results give an indication that supply of B-complex vitamins by ruminal microorganisms could be suboptimal for high-producing dairy cows, for example, in early lactation when fed a diet with a high proportion of concentrates. More research is needed to determine the metabolic consequences of these variations. Key words: Dairy cow, vitamin B6, vitamin B12, folic acid, lactation

scholarly journals Effects of Dietary Supplements of Folic Acid and Vitamin B12 on Metabolism of Dairy Cows in Early Lactation

2007 ◽  
Vol 90 (7) ◽  
pp. 3442-3455 ◽  
Author(s):  
B. Graulet ◽  
J.J. Matte ◽  
A. Desrochers ◽  
L. Doepel ◽  
M.-F. Palin ◽  
...  
Keyword(s):  
Folic Acid ◽  
Vitamin B12 ◽  
Dairy Cows ◽  
Dietary Supplements ◽  
Early Lactation

Response of serum concentrations of folates to dietary supplements of folic acid given to ewes during gestation

1999 ◽  
Vol 79 (3) ◽  
pp. 387-389 ◽  
Author(s):  
C. L. Girard ◽  
F. Castonguay ◽  
J. J. Matte
Keyword(s):  
Folic Acid ◽  
Key Words ◽  
Dietary Supplements ◽  
Vitamin B ◽  
Serum Concentrations

Serum folates were determined during the 24 h following the ingestion of 0, 130, 260 or 520 mg of folic acid at 12, 61 and 131 d of gestation in 38 ewes. The response of serum folates increased with the dose ingested (P < 0.0001) but decreased as gestation progressed (P < 0.005). Key words: Ewe, dietary supplements, folic acid, vitamin B12

An economic model evaluating the supplementation of folic acid and vitamin B12 given around parturition and in early lactation on dairy farms in Québec, Canada

2014 ◽  
Vol 94 (4) ◽  
pp. 737-747 ◽  
Author(s):  
M. Duplessis ◽  
C. L. Girard ◽  
D. E. Santschi ◽  
D. Pellerin
Keyword(s):  
Folic Acid ◽  
Dairy Cows ◽  
Economic Model ◽  
Metabolic Disorders ◽  
Dairy Farms ◽  
Dairy Herds ◽  
Vitamin B ◽  
Vitamin Supplement ◽  
Early Lactation ◽  
Actual Knowledge

Duplessis, M., Girard, C. L., Santschi, D. E. and Pellerin, D. 2014. An economic model evaluating the supplementation of folic acid and vitamin B12 given around parturition and in early lactation on dairy farms in Québec, Canada. Can. J. Anim. Sci. 94: 737–747. The aim of this study was to estimate the potential profitability of a combined supplement of folic acid and vitamin B12 given around parturition and in early lactation in commercial dairy herds in Québec. A total of 791 dairy cows from 14 herds were enrolled. Cows were assigned to weekly intramuscular injections of saline or 320 mg of folic acid and 10 mg of vitamin B12. Treatments began 3 wk before the expected calving date and lasted until 8 wk of lactation. Within each herd, data on production, reproduction, and incidence of metabolic disorders and other diseases were recorded. With regard to the Canadian dairy industry, which operates under a supply management system, two scenarios were studied: (1) quota kept constant and (2) number of cows kept constant. For scenarios 1 and 2, eight and seven herds out of 14, respectively, obtained a positive annual net margin per cow following the vitamin supplement. The average net margins were Can$31.18 and Can$–4.86 N cow−1 yr−1 for scenarios 1 and 2, respectively. The variability of the response highlights that supplies of these vitamins by ruminal synthesis were probably different among herds and actual knowledge does not allow predicting supplies according to the diet.

The effect of asynchronous diets on the function of the rumen in the lactating dairy cow

1998 ◽  
Vol 1998 ◽  
pp. 19-19
Author(s):  
A.R. Henderson ◽  
P.C. Garnsworthy ◽  
J.R. Newbold ◽  
P.J. Buttery
Keyword(s):  
Protein Synthesis ◽  
Dairy Cows ◽  
Dairy Cow ◽  
Production Performance ◽  
Early Lactation ◽  
Microbial Protein ◽  
Nutrient Flows ◽  
Lactating Dairy Cows ◽  
Overall Efficiency ◽  
Fermentation Parameters

Sinclair et al. (1993) found that a diet formulated to be synchronous with regard to hourly release of nitrogen and energy increased microbial protein synthesis by 14% in sheep. Dairy cows in early lactation experience a shortfall of energy and protein, with available protein determining the overall efficiency of metabolism (MacRae and Lobley, 1986) and subsequent milk production. It is therefore necessary to maximise microbial protein yield during this period. In this study diets were designed for lactating dairy cows to contain the same feed ingredients, but to release nitrogen and energy in the rumen at different times. Rumen fermentation parameters, nutrient flows to the small intestine and production performance were investigated.

scholarly journals Determination metabolic and nutritional status in dairy cows during early and mid lactation

2016 ◽  
Vol 32 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Radojica Djokovic ◽  
Zoran Ilic ◽  
Vladimir Kurcubic ◽  
Milan Petrovic ◽  
Violeta Caro-Petrovic ◽  
...  
Keyword(s):  
Blood Serum ◽  
Dairy Cows ◽  
Metabolic Status ◽  
Early Lactation ◽  
Serum Concentrations ◽  
Nonesterified Fatty Acids ◽  
Lactating Cows ◽  
Lower Blood ◽  
Positive Correlations ◽  
Beta Hydroxybutyrate

The objective of the present study was to investigate nutritional and metabolic status in Simmental cows during early and mid-lactation. Fifteen early lactating cows and 15 mid lactating cows were chosen for the investigation. Blood samples were collected to measure beta-hydroxybutyrate (BHB), nonesterified fatty acids (NEFA), triglycerides (TG), glucose and the activity of aspartate transaminase (AST). Early lactation as compared to mid lactating cows were found to have significantly higher (P<0.05) blood serum concentrations of NEFA, BHB and AST and lower blood serum concentrations of glucose (P<0.05) and TG (P>0.05). Significantly negative correlations were observed between BHB and glucose (P<0.01), BHB and TG (P<0.05), NEFA and glucose (P<0.05). Significantly positive correlations were observed between NEFA and BHB (P<0.05), NEFA and AST (P<0.05), glucose and TG (P<0.01). The results suggest that these parameters can serve as useful indicators of the nutritional and metabolic status of dairy cows during lactation.

scholarly journals PSI-18 Adiponectin serum concentrations in late pregnancy and early lactation in primiparous and multiparous Holstein dairy cows.

2018 ◽  
Vol 96 (suppl_3) ◽  
pp. 65-65
Author(s):  
C Urh ◽  
J Denißen ◽  
I Harder ◽  
C Koch ◽  
E Stamer ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Late Pregnancy ◽  
Early Lactation ◽  
Serum Concentrations ◽  
Holstein Dairy Cows

Response of early lactation dairy cows to the inclusion of the liver technology product ABN-LiFT in the total mixed ration

2002 ◽  
Vol 2002 ◽  
pp. 197-197
Author(s):  
C A Middlemass ◽  
C M Minter ◽  
M Marsden
Keyword(s):  
Folic Acid ◽  
Vitamin B12 ◽  
Dairy Cows ◽  
Energy Requirement ◽  
High Energy ◽  
Early Lactation ◽  
Dry Period ◽  
Total Mixed Ration ◽  
Methyl Group ◽  
Technology Product

Through the dry period to early lactation the cow goes through a dramatic change in her metabolism. To supply the high energy requirement in early lactation fat supply from the diet and body mobilisation increases substantially. As a result, the liver accumulates fat, the rate of detoxification slows down, ammonia accumulates and there’s a reduced supply of fat, glucose and protein to the udder. This trial was designed to evaluate the response of dairy cows to product called ABN-LiFT a proprietary mixture of B-group vitamins and methyl group donors (rumen protected choline, niacin, vitamin B12, biotin, folic acid and thiamine) designed to reduce the accumulation of triglycerides in the liver and accelerate VLDL export.

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