scholarly journals Treatment of Early Childhood Medulloblastoma by Postoperative Chemotherapy Alone—A Critical Review

2009 ◽  
Vol 3 ◽  
pp. CMO.S392 ◽  
Author(s):  
Ricardo J. Komotar ◽  
Marc L. Otten ◽  
Matthew C. Garrett ◽  
Richard C.E. Anderson
Keyword(s):  
Early Childhood ◽  
Critical Review ◽  
Postoperative Chemotherapy ◽  
Childhood Medulloblastoma

Treatment of Early Childhood Medulloblastoma by Postoperative Chemotherapy Alone

2005 ◽  
Vol 352 (10) ◽  
pp. 978-986 ◽  
Author(s):  
Stefan Rutkowski ◽  
Udo Bode ◽  
Frank Deinlein ◽  
Holger Ottensmeier ◽  
Monika Warmuth-Metz ◽  
...  
Keyword(s):  
Early Childhood ◽  
Postoperative Chemotherapy ◽  
Childhood Medulloblastoma

scholarly journals Treatment of early childhood medulloblastoma by postoperative chemotherapy and deferred radiotherapy

2009 ◽  
Vol 11 (2) ◽  
pp. 201-210 ◽  
Author(s):  
Stefan Rutkowski ◽  
Nicolas Ulrich Gerber ◽  
Katja von Hoff ◽  
Astrid Gnekow ◽  
Udo Bode ◽  
...  
Keyword(s):  
Early Childhood ◽  
Postoperative Chemotherapy ◽  
Childhood Medulloblastoma

Breastfeeding and early childhood caries: a critical review

2004 ◽  
Vol 80 (8) ◽  
pp. 199-210 ◽  
Author(s):  
Nilza M. E. Ribeiro ◽  
Manoel A. S. Ribeiro
Keyword(s):  
Early Childhood ◽  
Critical Review ◽  
Early Childhood Caries ◽  
Childhood Caries

Survival and Prognostic Factors of Early Childhood Medulloblastoma: An International Meta-Analysis

2010 ◽  
Vol 28 (33) ◽  
pp. 4961-4968 ◽  
Author(s):  
Stefan Rutkowski ◽  
Katja von Hoff ◽  
Angela Emser ◽  
Isabella Zwiener ◽  
Torsten Pietsch ◽  
...  
Keyword(s):  
Early Childhood ◽  
Prognostic Factors ◽  
Meta Analysis ◽  
Large Cell ◽  
Study Groups ◽  
National Study ◽  
Incomplete Resection ◽  
Histologic Subtype ◽  
Prospective Trials ◽  
Childhood Medulloblastoma

Purpose To assess the prognostic role of clinical parameters and histology in early childhood medulloblastoma. Patients and Methods Clinical and histologic data from 270 children younger than age 5 years diagnosed with medulloblastoma between March 1987 and July 2004 and treated within prospective trials of five national study groups were centrally analyzed. Results Two hundred sixty children with medulloblastoma and specified histologic subtype were eligible for analysis (median age, 1.89 years; median follow-up, 8.0 years). Rates for 8-year event-free survival (EFS) and overall survival (OS) were 55% and 76%, respectively, in 108 children with desmoplastic/nodular medulloblastoma (DNMB) or medulloblastoma with extensive nodularity (MBEN); 27% and 42%, respectively, in 145 children with classic medulloblastoma (CMB); and 14% and 14%, respectively, in seven children with large-cell/anaplastic (LC/A) medulloblastoma (P < .001). Histology (DNMB/MBEN: hazard ratio [HR], 0.44; 95% CI, 0.31 to 0.64; LC/A medulloblastoma: HR, 2.27; 95% CI, 0.95 to 5.54; P < .001 compared with CMB), incomplete resection and metastases (M0R1: HR, 1.86; 95% CI, 1.29 to 2.80; M+: HR, 2.28; 95% CI, 1.50 to 3.46; P < .001 compared with M0R0), and national group were independent prognostic factors for EFS, and OS. The HRs for OS ranged from 0.14 for localized M0 and DNMB/MBEN to 13.67 for metastatic LC/A medulloblastoma in different national groups. Conclusion Our results confirm the high frequency of desmoplastic variants of medulloblastomas in early childhood and histopathology as a strong independent prognostic factor. A controlled de-escalation of treatment may be appropriate for young children with DNMB and MBEN in future clinical trials.

Pendekatan modelling keperawatan anak pada orang tua dalam menstimulasi anak usia dini dengan masalah perubahan perilaku dengan kebiasaan menggunakan gadget

2020 ◽  
Vol 1 (1) ◽  
pp. 1-6
Author(s):  
Yola Suryani ◽  
Rini Palupi ◽  
Anggi Kusuma
Keyword(s):  
Early Childhood ◽  
Literature Review ◽  
Data Base ◽  
Critical Review ◽  
Full Text ◽  
Negative Impact ◽  
Self Control ◽  
Google Scholar ◽  
Social Unit ◽  
Children's Attitudes

Parents are the smallest social unit that has an important role and are the basis of children's development, where parents are the deciding factors for the successful formation of children's attitudes and behaviors. A mother who has children must have knowledge. Often we meet many parents who give gadgets to early childhood (3-6 years). The use of gadgets continuously will have a negative impact on children's behavior in their daily lives, children tend to be very dependent and become more emotional, get bored easily when someone advises, complains a lot, self-control is uncontrolled, personal is closed, health is disturbed, sleep disorders , aloof, mental illness, aggressive, addictive. This literature review uses critical review of full text articles in the last ten years, from 2010-2020 in Indonesian and English. Because of the limitations of the article, quantitative studies are used to obtain a more accurate review. Google Scholar data base search, National Library of the Republic of Indonesia, PubMed, Proquest with the keywords “Role of Parents”, “Early Childhood”, “Gadgets”, “Modeling Approach “to get articles that match the topic and purpose. 47 articles in Google Scholar, Then the article is read intensively and a summary of each article is made. Knowledge of the mother who is the closest person to the child in health care has a significant influence on children's attitudes and behavior in looking after and educating children. It is recommended that mothers of children aged 3-6 years give gadgets to their children and choose applications according to their age, and limit the time to use gadgets so that children do not experience addiction so that children can adapt to the environment and avoid developmental delays, especially social and emotional. Abstrak: Orangtua merupakan unit sosial terkecil yang memiliki peranan penting dan menjadi dasar perkembangan anak, dimana orang tua menjadi faktor penentu bagi keberhasilan pembentukan sikap dan perilaku anak. Seorang ibu yang memiliki anak wajib memiliki pengetahuan. Sering kita temui banyak orang tua yang memberikan gadget pada anak usia dini (3-6 tahun). Penggunaan gadget secara terus-menerus akan berdampak buruk bagi perilaku anak dalam kesehariannya, anak-anak cenderung akan sangat tergantung dan menjadi lebih emosional, cepat bosan ketika ada yang menasehati, banyak mengeluh, egois tidak terkendali, pribadi yang tertutup, kesehatan terganggu, gangguan tidur, suka menyendiri, penyakit mental, agresif, adikasi. Literature review ini memakai critical review artikel full text sepuluh tahun terakhir  yaitu  dari  tahun  2010-2020  dalam  bahasa indonesia dan bahasa inggris. Karena keterbatasan  artikel  maka  digunakan  studi  kuantitatif untuk mendapatkan hasil review yang lebih akurat. Pencarian data base Google Scholar, Perpustakaan Nasional Republik Indonesia, PubMed, Proquest dengan kata kunci “Peran Orang tua”, “Anak Usia Dini”, “Gadget”, “Pendekatan Modelling” untuk mendapatkan artikel yang sesuai dengan topik dan tujuan. Didapatkan 47 artikel di Google Scholar, Selanjutnya   dilakukan   pembacaan   artikel secara intensif dan dibuatkan ringkasan dari setiap artikel. Pengetahuan ibu yang merupakan orang terdekat dengan anak dalam pemeliharaan kesehatan memberikan pengaruh yang signifikan terhadap sikap dan perilaku anak dalam menjaga dan mendidik anak. Sebaiknya ibu anak usia(3-6tahun) memberikan gadget kepada anaknya dan memilih aplikasi sesuai dengan usianya, serta membatasi waktu penggunaan gadget agar anak tidak mengalami kecanduan sehingg aanak dapat beradaptasi dengan lingkungan dan terhindar dari keterlambatan perkembangan khususnya social dan emosional.

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