Psychiatric Manifestations in a Patient with Both Huntington's Disease and Hyperthyroidism: A Case Report

2020 ◽  
Vol 34 (4) ◽  
pp. 199
Author(s):  
Te-Jen Lai ◽  
Chun-Te Lee ◽  
Yu-Tung Lee
Keyword(s):  
Case Report ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Psychiatric Manifestations

“organic Personality Disorder” as Part of Early Neuropsychiatric Manifestations in Huntington’s Disease - a Case Report

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
J. Maia
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Psychiatric Symptoms ◽  
Age Of Onset ◽  
Neuropsychiatric Symptoms ◽  
Personality Change ◽  
Psychotic Symptoms ◽  
Autosomal Dominant Disorder ◽  
Neuropsychiatric Manifestations ◽  
Psychiatric Manifestations

Huntington's Disease (HD) is an inherited autosomal dominant disorder characterized by motor, cognitive and psychiatric symptomatology, being considered a paradigmatic neuropsychiatric disorder that includes all three components of the "Triadic Syndromes": dyskinesia, dementia and depression.Firstly described in 1872 as an "Hereditary Chorea" by George Huntington only in 1993 was its responsible gene identified. A person who inherits the HD gene will sooner or later develop the disease. the age of onset, early signs and rate of disease progression vary greatly from person to person.Neuropsychiatric symptoms are an integral part of HD and have been considered the earliest markers of the disease, presenting sometimes more than 10 years before a formal diagnosis is done. Patients may experience dysphoria, mood swings, agitation, irritability, hostile outbursts, psychotic symptoms and deep bouts of depression with suicidal ideation. Personality change is reported in 48% of the cases, with the paranoid subtype being described as the most prevalent. the clinical case presented illustrates a case of HD which started with insidious psychiatric symptoms and an important personality change.Despite a wide number of medications being prescribed to help control emotional, movement and behaviour problems, there is still no treatment to stop or reverse the course of the disease. Furthermore, psychiatric manifestations are often amenable to treatment, and relief of these symptoms may provide significant improvement in patient's and caregivers quality of life.A greater awarness of psychiatric manifestations of HD is essential to an earlier diagnosis and an optimized therapeutic approach.

Deep brain stimulation in Huntington's disease: A 4-year follow-up case report

2012 ◽  
Vol 27 (6) ◽  
pp. 806-807 ◽  
Author(s):  
Sabine Spielberger ◽  
Anna Hotter ◽  
Elisabeth Wolf ◽  
Wilhelm Eisner ◽  
Jörg Müller ◽  
...  
Keyword(s):  
Case Report ◽  
Deep Brain Stimulation ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Brain Stimulation ◽  
Deep Brain

Quetiapine in Huntington's disease: a first case report

2002 ◽  
Vol 249 (8) ◽  
pp. 1114-1115 ◽  
Author(s):  
Raphael M. Bonelli ◽  
Gerald Niederwieser
Keyword(s):  
Case Report ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
First Case

Late-Onset Huntington's Disease: A Geriatric Psychiatry Perspective

1996 ◽  
Vol 9 (1) ◽  
pp. 26-29 ◽  
Author(s):  
Kenneth I. Shulman ◽  
Anne Lennox ◽  
Harry Karlinsky
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Elderly Patients ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Psychiatric Symptoms ◽  
Late Onset ◽  
Clinical Aspects ◽  
Illustrative Case ◽  
Wide Range

Late-onset Huntington's disease is more common than has been generally appreciated and is associated with a wide range of psychiatric symptoms and syndromes. Geriatric psychiatrists have an important role to play in establishing the diagnosis and providing guidance to elderly patients and their families as they struggle with difficult management decisions. An illustrative case report and selective literature review are presented that highlight the genetic and clinical aspects of the condition.

Perospirone in treatment of Huntington's disease: A first case report

2007 ◽  
Vol 31 (1) ◽  
pp. 308-310 ◽  
Author(s):  
Tomohide Roppongi ◽  
Takashi Togo ◽  
Shinichi Nakamura ◽  
Takeshi Asami ◽  
Asuka Yoshimi ◽  
...  
Keyword(s):  
Case Report ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
First Case

scholarly journals Psychotic depression as an initial symptom of Huntington’s disease – a case report

2016 ◽  
Vol 4 ◽  
pp. 148-151 ◽  
Author(s):  
Joanna Salagierska ◽  
Agnieszka Remlinger-Molenda ◽  
Daniel Zielonka ◽  
Janusz Rybakowski
Keyword(s):  
Case Report ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Initial Symptom ◽  
Psychotic Depression
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