scholarly journals Diagnostic value of ground-glass opacity in suspected coronavirus disease 2019 patients: A meta-analysis

2021 ◽  
Vol 8 (1) ◽  
pp. 31
Author(s):  
Jie Qin ◽  
Yanqiu Zhu ◽  
Cui Yan ◽  
Yani Duan ◽  
Leilei Tang ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Ground Glass Opacity ◽  
Diagnostic Value ◽  
Ground Glass

scholarly journals Can CT imaging features of ground-glass opacity predict invasiveness? A meta-analysis

2018 ◽  
Vol 9 (4) ◽  
pp. 452-458 ◽  
Author(s):  
Jian Dai ◽  
Guoyou Yu ◽  
Jianqiang Yu
Keyword(s):  
Meta Analysis ◽  
Ground Glass Opacity ◽  
Ct Imaging ◽  
Ground Glass ◽  
Imaging Features

scholarly journals The Epidemiology of Ground Glass Opacity Lung Adenocarcinoma: A Network-Based Cumulative Meta-Analysis

2020 ◽  
Vol 10 ◽  
Author(s):  
Xiongfei Li ◽  
Fan Ren ◽  
Shuhang Wang ◽  
Zhicheng He ◽  
Zuoqing Song ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Meta Analysis ◽  
Ground Glass Opacity ◽  
Ground Glass

Distinct clinical characteristics and prognosis of ground-glass opacity-type lung cancer: A systematic review and meta-analysis.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e20505-e20505
Author(s):  
Ren Chongxi ◽  
Yin Ruisheng ◽  
Wang Hongqiao ◽  
Wang Hongchen ◽  
Zhou Tong ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Systematic Review ◽  
Early Stage ◽  
Meta Analysis ◽  
Treatment Strategies ◽  
Ground Glass Opacity ◽  
Clinicopathological Characteristics ◽  
Ground Glass ◽  
Survival Outcomes ◽  
Early Stage Lung Cancer

e20505 Background: Lung ground-glass opacity (GGO), a hazy increased opacity on computed tomography with preservation of bronchial and vascular margins, has been shown to be associated with early-stage lung cancer. With the increasing prevalence of ground-glass opacity-type lung cancer (GGO-LC), more researches have focused on the diagnosis and treatment of this early stage lung cancer; however, the clinical characteristics and survival outcomes of this disease has not yet been fully elucidated. Aim: To analyze and review the clinicopathological characteristics for GGO-LC and to identify the optimal treatment strategies in this select population. A systematic review and meta-analysis of the literature were carried out. The study was registered (CRD42021228774). Methods: We did a systematic review and meta-analysis of observational studies published from database inception to June 30, 2020, which reported on clinicopathological characteristics, management and survival outcomes in patients with GGO-LC. Studies were identified by searches in PubMed, MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, and by hand searching of previous publications. We extracted the general information to perform the meta-analysis, mainly focusing on age, gender, and smoking status. We also extracted treatment and prognosis information to assess the effect of treatment strategies on overall survival (OS). Robustness of pooled estimates from random-effects models was considered with sensitivity analyses, meta-regression, and subgroup analyses. All statistical analyses were performed with Stata 16.0. Results: Data on 9444 patients in 27 observational studies were included. GGO-type lung cancer was typically characterized as non-invasively or minimally invasively low-grade adenocarcinomas. Therapeutic intervention for these early stage lung cancers was an important opportunity for decreasing overall mortality of lung cancer. The final pooled analysis showed that the average age at diagnosis, female proportion and non-smoking proportion of patients with GGO-LC was 57.7 (95% CI, 53.9-61.5, P < 0.001, I2 = 92.9%), 0.591 (95% CI, 0.563-0.619, P < 0.001, I2 = 86.7%), and 0.631 (95% CI, 0.556-0.706, P < 0.001, I2 = 98.3%), respectively. The pooled overall survival rate was 96.2% (95% CI, 0.954 to 0.970, P < 0.001, I2 = 78.9%). The results showed that the majority of GGO-LC patients had good survival outcomes, presenting a significant proportion of young, female and non-or light smokers. Conclusions: From our analysis, it demonstrates that the patients with GGO-LC may be relatively young females and non-or light smoking history, and had better prognosis. However, there are some limitations in the present study, and more evidence is necessary to wait for more results from RCT to draw a valid conclusion.

scholarly journals Clinical characterization and chest CT findings in laboratory-confirmed COVID-19: a systematic review and meta-analysis

2020 ◽  
Author(s):  
Golnaz Vaseghi ◽  
Marjan Mansourian ◽  
Raheleh Karimi ◽  
Kiyan Heshmat-Ghahdarijani ◽  
Sadegh Baradaran Mahdavi ◽  
...  
Keyword(s):  
Fixed Effects ◽  
Clinical Symptoms ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Ground Glass Opacity ◽  
Ground Glass ◽  
Cochrane Library ◽  
Analysis Model ◽  
Ct Findings

AbstractBackgroundImagery techniques have been used as essential parts of diagnostic workup for patients suspected for 2019-nCoV infection, Multiple studies have reported the features of chest computed tomography (CT) scans among a number of 2019-nCoV patients.MethodStudy Identification was carried out in databases (PubMed, Embase and Cochrane Library) to identify published studies examining the diagnosis, the 2019 novel coronavirus (2019-nCoV). Heterogeneity among reported prevalence was assessed by computing p-values of Cochrane Q-test and I2 -statics. The pooled prevalence of treatment failure was carried out with a fixed effects meta-analysis model, generating the pooled 95% confidence interval. A random-effect model was used to pool the results since this model could incorporate the heterogeneity of the studies and therefore proved a more generalized result.ResultsAccording to the combined results of meta-analysis, the total 55% of corona patients were males. The mean age of the patients was 41.31 (34.14, 48.47). Two prevalent clinical symptoms between patients were fever, cough with prevalence of 85%, and 62%, respectively. Either Ground Glass Opacity GGO or consolidation was seen in 86% but 14% had NO GGO or consolidation.The other rare CT symptoms were pericardial effusion, and pleural effusion with 4, 5, 7% prevalence, respectively. The most prevalent event was Either GGO or consolidation in 85% of patients.ConclusionThe most CT-scan abnormality is Either Ground Glass Opacity GGO or consolidation however in few patients none of them might be observed, so trusting in just CT findings will lead to miss some patients.

Sign in / Sign up

Export Citation Format

Share Document