Study of antidiabetic properties of Uvaria narum leaf extract through glucose uptake and glucose transporter 4 expression studies in 3T3L1 cell line model

2019 ◽  
Vol 11 (3) ◽  
pp. 304
Author(s):  
SurapaneniKrishna Mohan ◽  
Murad Alsawalha ◽  
PB Janardhana ◽  
KR Padma ◽  
ShivaShankar Reddy ◽  
...  
Keyword(s):  
Glucose Uptake ◽  
Cell Line ◽  
Leaf Extract ◽  
Glucose Transporter ◽  
Glucose Transporter 4 ◽  
Line Model ◽  
Cell Line Model ◽  
Expression Studies ◽  
3T3l1 Cell

scholarly journals Effect of Litsea lancifolia leaf extract on glucose transporter 4 translocation and glucose uptake in 3T3L1 cell line

2019 ◽  
Vol 11 (3) ◽  
pp. 240
Author(s):  
SurapaneniKrishna Mohan ◽  
Murad Alsawalha ◽  
AbeerMohammed Al-Subaie ◽  
ReemYousuf Al-Jindan ◽  
SrinivasaRao Bolla ◽  
...  
Keyword(s):  
Glucose Uptake ◽  
Cell Line ◽  
Leaf Extract ◽  
Glucose Transporter ◽  
Glucose Transporter 4 ◽  
3T3l1 Cell

Anti-diabetic activities of Dactylorhiza hatagirea leaf extract in 3T3-L1 cell line model

2019 ◽  
Vol 15 (64) ◽  
pp. 212
Author(s):  
SurapaneniKrishna Mohan ◽  
Murad Alsawalha ◽  
AbeerMohammed Al-Subaei ◽  
ReemYousuf Al-Jindan ◽  
SrinivasaRao Bolla ◽  
...  
Keyword(s):  
Cell Line ◽  
Leaf Extract ◽  
Line Model ◽  
Cell Line Model

scholarly journals Adaptation to G93Asuperoxide dismutase 1 in a motor neuron cell line model of amyotrophic lateral sclerosis

FEBS Journal ◽  
2009 ◽  
Vol 276 (10) ◽  
pp. 2861-2874 ◽  
Author(s):  
Silvia Tartari ◽  
Giuseppina D’Alessandro ◽  
Elisabetta Babetto ◽  
Milena Rizzardini ◽  
Laura Conforti ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Motor Neuron ◽  
Cell Line ◽  
Line Model ◽  
Cell Line Model ◽  
Lateral Sclerosis

A cell line model of mucin biosynthesis in the human intestine

1996 ◽  
Vol 48 (1) ◽  
pp. A36-A37
Author(s):  
B VANKLINKEN ◽  
E OUSSOREN ◽  
J WEENINK ◽  
H BULLER ◽  
J DEKKER ◽  
...  
Keyword(s):  
Cell Line ◽  
Human Intestine ◽  
Line Model ◽  
Cell Line Model ◽  
A Cell

scholarly journals Activity of EGFR, mTOR and PI3K inhibitors in an isogenic breast cell line model

2014 ◽  
Vol 7 (1) ◽  
pp. 397 ◽  
Author(s):  
Sharon Glaysher ◽  
Louise M Bolton ◽  
Penny Johnson ◽  
Christopher Torrance ◽  
Ian A Cree
Keyword(s):  
Cell Line ◽  
Breast Cell Line ◽  
Line Model ◽  
Pi3k Inhibitors ◽  
Cell Line Model

Characterization of Alternatively Spliced Isoforms of MUC4 and ADAM12 Genes in a Metastatic Colorectal Cancer Cell Line Model

2021 ◽  
Author(s):  
Saleh Althenayyan ◽  
Mohammed H AlMuhanna ◽  
Abdulkareem Al Abdulrahman ◽  
Bandar Alghanem ◽  
Suliman A. Alsagaby ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Metastatic Colorectal Cancer ◽  
Cell Line ◽  
Differential Expression ◽  
Cell Lines ◽  
Cancer Cell ◽  
Colorectal Cancer Cell ◽  
Line Model ◽  
Cell Line Model ◽  
Alternatively Spliced

Colorectal cancer prognosis get worse with advancement of disease into metastatic stage. There is a pertinent need to develop prognostic biomarkers that can be used for personalized and precision medicine. Alternative splicing provides an insight into understanding of changes at isoform expression level which may not be evident at gene level. In this direction, we utilized our prior knowledge about significant alternatively spliced genes and chose ADAM12 and MUC4 for further characterization in a metastatic cell line model. These genes were found to be good prognostic indicators in The Cancer Genome Atlas database. We studied the gene organization and designed primers to specifically amplify a group of isoforms. Differential expression of these group of isoforms was observed in normal, primary and metastatic colorectal cancer cell lines. We further validated the results using sanger sequencing. Isoform expression was found to respond to the 5-fluorouracil treatment. RNAseq analysis of the cell lines further validated the differential expression of gene isoforms. Successful detection of ADAM12 and MUC4 in cell lysates varied according to the antibody used which may reflect differential expression of isoforms. This comprehensive study underscores the importance of studying alternatively spliced isoforms and their probable used as prognostic or predictive biomarkers.

scholarly journals Dysregulation of the IFN-γ-STAT1 signaling pathway in a cell line model of large granular lymphocyte leukemia

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0193429 ◽  
Author(s):  
Paige M. Kulling ◽  
Kristine C. Olson ◽  
Cait E. Hamele ◽  
Mariella F. Toro ◽  
Su-Fern Tan ◽  
...  
Keyword(s):  
Cell Line ◽  
Signaling Pathway ◽  
Large Granular Lymphocyte ◽  
Line Model ◽  
Large Granular Lymphocyte Leukemia ◽  
Cell Line Model ◽  
A Cell ◽  
Stat1 Signaling ◽  
Ifn Γ

In vitro antioxidant activities of Rhodobacter sphaeroides and protective effect on Caco-2 cell line model

2018 ◽  
Vol 103 (2) ◽  
pp. 917-927 ◽  
Author(s):  
Jun An ◽  
Cui Yang ◽  
Zuming Li ◽  
Patricia W. Finn ◽  
David L. Perkins ◽  
...  
Keyword(s):  
Protective Effect ◽  
Cell Line ◽  
Rhodobacter Sphaeroides ◽  
Antioxidant Activities ◽  
Line Model ◽  
Cell Line Model

scholarly journals A xenograft and cell line model of SDH-deficient pheochromocytoma derived from Sdhb+/− rats

2020 ◽  
Vol 27 (10) ◽  
pp. X9-X10
Author(s):  
James F Powers ◽  
Brent Cochran ◽  
James D Baleja ◽  
Hadley D Sikes ◽  
Andrew D Pattison ◽  
...  
Keyword(s):  
Cell Line ◽  
Line Model ◽  
Cell Line Model
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