scholarly journals An oral cavity profile in illicit- Drug abusers?

2019 ◽  
Vol 23 (6) ◽  
pp. 517
Author(s):  
MuhammadMahmoud Al Bush
2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Parastoo Hassani Abharian ◽  
Parvin Dehghan ◽  
Peyman Hassani Abharian ◽  
Sepideh Tolouei

  Background and Purpose: Candida dubliniensis is closely related to the most pathogenic and prevalent yeast, namely C. albicans. Candida species can opportunistically overgrow in vulnerable individuals and cause a variety of diseases. The current study aimed to identify and isolate C. dubliniensis species present in the Candida albicans species complex identified in the oral cavity of drug abusers. Materials and Methods: This study was conducted on 53 strains of C. albicans species complex, isolated from the oral mucosa of drug abusers in Isfahan, Iran. DNA extraction was accomplished through boiling procedure. Duplex polymerase chain reaction (PCR) was performed to amplify ITS1-5.8S-ITS2 region using four specific primers. Fungal species were identified based on the difference in the size of the bands created in the Agarose gel. Results: Out of the 53 isolates under study, 30 (56.6%) and 14 (26.4%) samples were identified as C. albicans and C. dubliniensis, respectively. In the remaining 9 samples (17%), both types of Candida species were confirmed. Conclusion: The findings of the present study revealed the presence of a noticeable amount of C. dubliniensis in the oral cavity of drug abusers. Therefore, the probable presence of this fungus should be considered during the examination of oral infection among this group. To date, no research has directly investigated this issue in Iran.


1987 ◽  
Vol 18 (4) ◽  
pp. 483-497 ◽  
Author(s):  
Richard C. Page ◽  
Bert O. Richmond ◽  
Marcelo De La Serna

2013 ◽  
Vol 6 (2) ◽  
pp. S24
Author(s):  
Salem Badr ◽  
Hironori Kitabata ◽  
Israel Barbash ◽  
Sa'ar Minha ◽  
Joshua Loh ◽  
...  

CHEST Journal ◽  
2013 ◽  
Vol 144 (4) ◽  
pp. 908A
Author(s):  
Jose Antony Paul ◽  
Varun Kumar ◽  
Vinay Huliyar ◽  
Hasnain Bawaadam ◽  
Vinod Khatri ◽  
...  

2015 ◽  
Vol 4 (1) ◽  
pp. 39-46
Author(s):  
Mohammad Kalantari Meibodi ◽  
Samira Esfandyari ◽  
Vahid Siyabi ◽  
Sareh Roosta

Background: Motor vehicle Traffic injuries are indeed one of the most important worldwide health problems. Opioids can induce a depressant effect on the central nervous system which may increase the risk of traffic accidents. This cross-sectional case-control study was conducted in Marvdasht, Iran to investigate the presence of drugs in hospitalized non-fatally injured drivers of motor vehicles.Materials and Methods: The cases were 500 drivers of motor vehicle, injured in the road traffic accident and referred to the emergency ward. The controls were 500 patients hospitalized in the same emergency department due to non-traumatic reasons. They were asked about the abuse of any substance during the 72 hours before their referral to the hospital. Urinary samples of patients with negative history of drug consumption were analyzed.Results: From the drivers, 237 (47.4%) of the case group and 278 (55.6%) of the control group had positive-substance consumption. Opium was the common drug abused in the two groups. An eight fold increased risk of road accident was observed for drivers who had used tramadol (OR= 8.2, 95% CI 4.9-13.7, p<0.001). Two or more illicit drugs (poly drug abuse) were detected in 24% of the cases and 31.8% of the controls (50.6% and 57.2% of drug abusers, respectively). Just for tramadol, the prevalence was higher in cases than controls. Conclusion: The results demonstrate the high proportion of illicit drug abuse among Iranian drivers. More health education and policies are necessary to steadily decrease drug abuse in our society.


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