scholarly journals Prevalence of depression in breast cancer patients and its association with their quality of life: A cross-sectional observational study

2017 ◽  
Vol 23 (3) ◽  
pp. 268 ◽  
Author(s):  
Chitra Venkateswaran ◽  
Debasweta Purkayastha ◽  
Kesavankutty Nayar ◽  
UG Unnikrishnan
2020 ◽  
Author(s):  
Tamrat Alem ◽  
Dabere Nigatu ◽  
Amsalu Birara ◽  
Tamene Fetene ◽  
Mastewal Giza

Abstract BackgroundAlthough breast cancer has a markedly higher incidence in developed countries, 50% of the new diagnosis and 70% of deaths occur in developing countries. There are limited data available on the quality of life among breast cancer patients in Ethiopia, notably in the Amhara region. This study aimed to assess the quality of life and associated factors among patients with breast cancer in the Amhara Region, Ethiopia, 2019.MethodsInstitutional based cross-sectional study was conducted from March 25 to July 7/2019 among 256 patients with breast cancer in the Amhara region. A systematic random sampling technique was used. Data were collected by using a standardized interviewer-administered Amharic version of the European Organization for research and treatment of cancer quality of life questionnaire core 30(EORTC QLQ C30) and breast cancer supplementary measure (QLQ-BR23). Data were analyzed by SPSS version 23. A binary logistic regression model was fitted to identify the associated factors. The odds ratio (OR) with 95% confidence interval (CI) was used to measure the strength of association.ResultsSixty-eight point four percent (68.4%) of breast cancer patient's QoL was poor. The mean score of quality of life was 70.6(standard deviation (SD) ±13.9; 95% CI: 69.0-72.4). All functional component scores were less than 75, from the symptom scale; diarrhea (11.6), constipation (17.5), and dyspnea (24.7) were less noticeable. Unmarried patients (AOR=2.59, 95% CI: 1.32-5.07), poor (AOR=2.39, 95%CI: 1.32-5.03), non housewife (AOR=3.25, 95% CI: 1.16-7.22), and complaints to dyspnea (AOR=3.48, 95% CI: 1.79-6.79), and insomnia (AOR=2.03, 95% CI: 1.05-3.91) were significantly associated with quality of life.ConclusionsHealth care professionals should give attention to unmarried, and non-housewife breast cancer patients, besides the treatment to improve the health of breast cancer patients.


2021 ◽  
Author(s):  
Jun-He Zhou ◽  
Wei-Han Li ◽  
De-Long Zhang ◽  
Bai-Le Ning ◽  
Lin Zhao ◽  
...  

Abstract Background: Depression has a high incidence among patients with breast cancer, but the relationship between depression and cancer-related physiological changes is not clear.Objectives: To explore the effect of T lymphocytes on breast cancer depression and the patient’s quality of life.Methods: This is a cross-sectional study. A total of 93 breast cancer patients with depression were recruited, 46 of whom underwent T lymphocyte, cortisol, BDNF, TNF-α, and IL-1β collection. We analysed the correlation between the indicators in these 46 participants and constructed two intermediary structural equations between their T lymphocytes and depression, as well as their T lymphocytes and their quality of life.Results: The results showed that CD4+ had a positive correlation with BDNF (r=0.334, P=0.023) and that BDNF had a negative correlation with HAMD-24 (r=-0.390, P=0.007). Both CD3+ and CD8+ cells were negatively correlated with cortisol (r=-0.358, P=0.015, r=-0.411, P=0.005), and cortisol was positively correlated with FACT-B (r=0.435, P=0.003). The equations including CD4+, BDNF, and HAMD-24, as well as the equations including CD3+, CD8+, cortisol, and FACT-B, were established. BDNF was the mediating variable between CD4+ and HAMD-24. Cortisol was the mediating variable between CD3+, CD8+ and FACT-B. Neither HAMD-24 nor FACT-B could form a direct path with T lymphocytes.Conclusion: T lymphocytes may be involved in the depression of breast cancer patients since a poor quality of life could inhibit T lymphocytes, and this may be the underlying physiological cause of breast cancer-related depression.


2020 ◽  
Author(s):  
Sanjiv Srivast ◽  
Alpana Srivast ◽  
Sandeep Tiwari

Abstract BackgroundBreast cancer is the commonest of all cancers among women across the world and India being no exception to this deadly disease. There may be many symptoms due to cancer, some are complex but some are not complex. Measuring quality of life (QoL) is important to measure overall burden of disease. It is important to evaluate cancer specific QoL which is associated to all stages of this disease. Also Quality of Life is a term that adds various dimensions of quality of life such as physical, psychological, socio-economical, spiritual, cognitional & social dimensions. Balance between all the four domains (i.e. Physical, Psychological, Social and Spiritual) means good quality of life, but in India QoL in general is not good and if we talk of cancer patients its worst.ObjectiveThe aim of this study is assessment of QoL in breast cancer patients undergoing treatment through various modalities at different stages of disease.MethodsThis is a cross-sectional study, a total of 150 breast cancer patients were included. Patients quality of life were assessed by Ferrel‘s Quality of Life Instrument-Breast Cancer patient version and the instrument is already validated by Ferrel BR et al (2012). These questionnaires consist of general well-being, psychological well-being, distress, fearfulness, social concerns and spiritual well-being. The data obtained gives Cronbach alpha value of 0.642 which is reliable enough for further study. The QoL in for most subjects was around 50% and is a cause of concern as this is quite low as compare to global standards. ResultsA significant relationship between type of cancer, amount of pain, and fatigue (tiredness) was found. However, none of the demographic variables (age, marital status, income) were significantly related to QoL. Education and type of treatment were found to be correlated with QoL. The physical well-being score was found to be Mean = 4.82, SD = 2.19. The Psychological well-being score was found to be Mean=4.95, SD=2.02. For social well-being score was found to be Mean=4.98, SD=1.94. The highest score was for spiritual well-being Mean = 5.32, SD = 2.46.ConclusionInfluencing quality of life (QoL) is an important issue in Breast cancer patients. Apart from effect of treatment there are other factors like socioeconomic status, psychological well-being, fear of recurrence etc., Which plays a pivotal role in patients wellbeing and if counseled at various levels like family, hospital and society can improve QoL.


2011 ◽  
pp. 98-105
Author(s):  
Nguyen Thai Bao Nguyen ◽  
Dinh Tung Nguyen ◽  
Vu Quoc Huy Nguyen

Background: The assessment and improvement of Quality of life (QoL) of breast cancer and other diseases patients have been of great concern for a long time. This research is to assessing the QoL of breast cancer patients using the popular and recommended instruments, the FACT-G, SF-36 and QLQ-C30 (including QLQ-BR23). Methods and Materials: A cross-sectional descriptive study on breast cancer patients receiving surgical, chemotherapy and radiotherapy, using FACT-G, SF-36 and QLQ-C30 to evaluate their quality of life. The assessment is mainly based on the patients’ own feelings. Results: Average age: 48.4±13.1. Most patients in the sample are from stage IIA to stage IIIB (TNM Cancer Staging, by AJCC 2010). Quality of life index using FACT-G is 60.6±5.1, using SF-36 is 46.5±11.0 in physical health and 53.1±14.8 in mental health, using QLQ-C30 is 53.1±21.0. Conclusion: The QoL assessment by using these instruments shows results mostly in average on many aspects. The screening needs to be improved for better early-detection and treatment, especially in mental care. Quality of life of breast cancer patients reasearches should be paid more attention and widely expanded.


2020 ◽  
Vol 20 (3) ◽  
pp. 990
Author(s):  
Debbie Nomiko

Breast cancer is a disease that occurs due to excessive growth or uncontrolled development of cells or breast tissue. Quality of life is an important goal in the treatment of cancer, and concerns about physical, psychological, body image disorders. The purpose of this study is to find out the factors related to the quality of life of breast cancer patients at Raden Mattaher Jambi Hospital in 2019. Research uses a coelative descriptive research design with a cross sectional approach. The research population is breast cancer patients who are treating at Raden Mattaher Jambi Hospital. Sampling is done on a sampling quota. Data collection instruments use the respondent's characteristic data questionnaire, coping mechanism, and quality of life questionnaire using the EORTC-QLQ 30 format. The data was analyzed univariate and bivariate with the Kai-Squared test (CI 95%). The results of the study obtained the average age of respondents was 51.8 years, the majority were elementary and high school educated with a proportion of 35.7%, and most did not work as many as 35 people (62.5%). The results of bivariate analysis that there is a relationship between the length of the cancer and the mechanism of coffee and the quality of life of breast cancer patients in Raden Mattaher Jambi Hospital. It is hoped that hospitals can facilitate the interaction activities of cancer patients through the formation of groups for cancer patients so that they can share experiences and information in terms of improving quality of life. For nursing research, it is hoped that this research can be the basic data in carrying out the next research.


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