scholarly journals Comparison of topical and intracameral nonsteroidal anti-inflammatory drugs on pupillary size and postoperative inflammation in cataract surgery

2021 ◽  
Vol 22 (3) ◽  
pp. 201
Author(s):  
ZeiadH ◽  
Ahmed Howaidy ◽  
Hazem Abdelmotaal
Keyword(s):  
Cataract Surgery ◽  
Postoperative Inflammation ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Pupillary Size

Topical Nonsteroidal Anti-Inflammatory Drugs in Uncomplicated Cataract Surgery: Effect of Sodium Naproxen

2005 ◽  
Vol 15 (5) ◽  
pp. 598-606 ◽  
Author(s):  
P. Russo ◽  
V. Papa ◽  
S. Russo ◽  
A. Dl Bella ◽  
G. Pabst ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Ophthalmic Solution ◽  
Controlled Study ◽  
Topical Formulation ◽  
Serious Adverse Events ◽  
Suitable Alternative ◽  
Postoperative Inflammation ◽  
Sodium Naproxen ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Purpose To investigate whether topical nonsteroidal anti inflammatory drugs (NSAIDs) are useful, in the absence of concomitant corticosteroid therapy, in limiting postoperative inflammation after uncomplicated cataract surgery. Methods A total of 328 patients were enrolled in a prospective, randomized, double-masked, parallel-group, active-controlled study. Anterior chamber inflammation (ACI) was evaluated as the primary efficacy parameter. Only patients with moderate inflammation (ACI score of ≤4) the day after surgery were randomized and treated with NSAIDs. A novel topical formulation containing 0.2% sodium naproxen was compared with 0.1% diclofenac. Both were administered three times a day for 14 consecutive days. Ocular inflammation was measured after 7 and 14 days by using slit-lamp biomicroscopy. Safety parameters were also evaluated at the same time. Results Both treatments were equally effective in controlling postsurgical inflammation. No statistically significant differences between treatment groups were observed for the safety variables. No serious adverse events (AEs) occurred during the course of the study. The most frequent AE reported with naproxen was eye redness. Conclusions NSAIDs can effectively be used without concurrent administration of corticosteroids to control postoperative inflammation after uncomplicated cataract surgery. In addition, naproxen ophthalmic solution may be considered a suitable alternative to the currently available NSAIDs.

Effect of Topical Nonsteroidal Anti-inflammatory Drugs on Pupillary Size During Uncomplicated Cataract Surgery

2017 ◽  
Vol 33 (4) ◽  
pp. 236-242 ◽  
Author(s):  
Alejandro Rodríguez-García ◽  
Julio C. Hernández-Camarena ◽  
Gilberto R. López-Jaime ◽  
José A. Nava-García
Keyword(s):  
Cataract Surgery ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Pupillary Size

scholarly journals Effect of anti-inflammatory regimen on early postoperative inflammation after cataract surgery

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jesper H. Erichsen ◽  
Julie L. Forman ◽  
Lars M. Holm ◽  
Line Kessel
Keyword(s):  
Cataract Surgery ◽  
Postoperative Inflammation ◽  
Anti Inflammatory
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