Sex Differences in antiaging response to short- and long-term high-intensity interval exercise in rat cardiac muscle: Telomerase activity, total antioxidant/oxidant status

2019 ◽  
Vol 62 (6) ◽  
pp. 261 ◽  
Author(s):  
Marziyeh Saghebjoo ◽  
Saber Sadeghi-Tabas ◽  
Iman Saffari ◽  
Azin Ghane ◽  
Ivan Dimauro
Keyword(s):  
Sex Differences ◽  
Cardiac Muscle ◽  
High Intensity ◽  
Telomerase Activity ◽  
Interval Exercise ◽  
Total Antioxidant ◽  
Short And Long Term ◽  
High Intensity Interval ◽  
Oxidant Status

scholarly journals Salivary and Plasmatic Antioxidant Profile following Continuous, Resistance, and High-Intensity Interval Exercise: Preliminary Study

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Adriele V. Souza ◽  
Jéssica S. Giolo ◽  
Renata R. Teixeira ◽  
Danielle D. Vilela ◽  
Leonardo G. Peixoto ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Exercise Intensity ◽  
High Intensity ◽  
Sports Medicine ◽  
Antioxidant Response ◽  
Interval Exercise ◽  
Antioxidant Profile ◽  
Exercise Adaptation ◽  
Total Antioxidant ◽  
High Intensity Interval

The increase in antioxidant responses promoted by regular physical activity is strongly associated with the attenuation of chronic oxidative stress and physiological mechanisms related to exercise adaptation. The aim of this work was to evaluate and compare how different exercise protocols (HIIE: high-intensity interval exercise, CE: continuous exercise, and RE: resistance exercise) may alter salivary and plasmatic antioxidants and salivary markers of exercise intensity and nitric oxide. Thirteen healthy, trained male subjects were submitted to the three exercise protocols. Blood and saliva samples were collected at the points preexercise, postexercise, and 3 hours postexercise. Antioxidants (total antioxidant capacity, superoxide dismutase and catalase activities, and levels of reduced glutathione and uric acid), markers of exercise intensity (salivary total protein and amylase activity), and salivary nitric oxide were evaluated. As a result, all exercise protocols increased the markers of exercise intensity and nitric oxide. Antioxidant response was increased after exercise, and it was found that a single HIIE session exerts a similar pattern of antioxidant response compared to CE, in plasma and saliva samples, while RE presented minor alterations. We suggest that HIIE may lead to alterations in antioxidants and consequently to the physiological processes related to redox, similar to the CE, with the advantage of being performed in a shorter time. In addition, the antioxidant profile of saliva samples showed to be very similar to that of plasma, suggesting that saliva may be an alternative and noninvasive tool in sports medicine for the study of antioxidants in different physical exercise protocols.

scholarly journals PO-58 The influence of different intensity exercise on DEN-induced hepatocellular carcinoma and liver metabonomic study

2018 ◽  
Vol 1 (3) ◽  
Author(s):  
Xue Zhang ◽  
Lu Cao ◽  
Zhengtang Qi ◽  
Shuzhe Ding
Keyword(s):  
Hepatocellular Carcinoma ◽  
Glutamic Acid ◽  
Palmitic Acid ◽  
Endurance Exercise ◽  
High Intensity ◽  
Exercise Group ◽  
Tumor Incidence ◽  
Interval Exercise ◽  
High Intensity Interval

Objective To study the influence of high internal intensity exercise and long-term moderate intensity endurance exercise on DEN-induced hepatocellular carcinoma (HCC) by metabonomics approach, and compare the anti-tumor effect between the different intensity exercise.  Methods From 8 to 26 weeks of age, mice with DEN treatment run on the treadmill at different intensity. NC: injection saline only. DEN: injection DEN only. HIT: treatment DEN, running on the treadmill at 1.5km/h, alternating run 2 minutes and rest 2 minutes for 40 minutes once a day, 5 days a week. ET: treatment DEN, running on the treadmill at o.8 km/h for 40 minutes once a day, 5 days a week. Gas chromatograph time-of-flight mass spectrometry (GC−TOFMS) test liver samples of mice and multi-dimensional statistical methods fond differential metabolites in all group. Results We observed that tumor incidence was similar between DEN and HIT; however, it was signicicantly smaller in ET compared to DEN and HIT. Orthogonal partial least squares analysis (OPLS) model was generated based on identified metabolites and showed clear discrimination from only DEN injection group and endurance exercise group, endurance exercise group and high intensity interval exercise group. Compared to DEN group, the level of galactinol, timonacic, glycine, cholesterol, carbamate and palmitic acid significantly decreased in endurance exercise group. Nevertheless, the level of malonic acid, ornithine and glutamic acid obviously increased in endurance group.  Conclusions Long-term endurance exercise inclines the hepatic tumor incidence by regulating the level of liver palmitic acid and glutamic acid metabolism . In addition, high intensity interval exercise does not have the effect to prevent tumor development.

scholarly journals Recovery from Different High-Intensity Interval Training Protocols: Comparing Well-Trained Women and Men

Sports ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 34
Author(s):  
Laura Hottenrott ◽  
Martin Möhle ◽  
Alexander Ide ◽  
Sascha Ketelhut ◽  
Oliver Stoll ◽  
...  
Keyword(s):  
Sex Differences ◽  
High Intensity ◽  
Interval Training ◽  
Fat Free Mass ◽  
Subjective Rating ◽  
Maximal Heart Rate ◽  
High Intensity Interval Training ◽  
Active Recovery ◽  
Training Response ◽  
High Intensity Interval

Due to physiological and anatomical sex differences, there are variations in the training response, and the recovery periods following exercise may be different. High-intensity interval training (HIIT) protocols are well-suited to differentially investigate the course of recovery. This study was conducted to determine sex-specific differences in the recovery following HIIT intervals interspersed with recovery phases of different lengths. Methods: Well-trained cyclists and triathletes (n = 11 females, n = 11 males) participated in this study. There were no significant sex differences in maximal heart rate (HR), relative peak power to body mass and fat-free mass, training volume, and VO2max-percentiles (females: 91.8 ± 5.5 %, males: 94.6 ± 5.4 %). A 30 s Wingate test was performed four times, separated by different active recovery periods (1, 3, or 10 min). Lactate, HR, oxygen uptake, and subjective rating of exertion and recovery were determined. Results: For the recovery time of three and ten minutes, men showed significantly higher lactate concentrations (p = 0.04, p = 0.004). Contrary, HR recovery and subjective recovery were significant slower in women than in men. Conclusion: During HIIT, women may be more resistant to fatigue and have a greater ability to recover metabolically, but have a slower HR and subjective recovery.

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